{"id":16035,"date":"2021-02-20T21:09:43","date_gmt":"2021-02-21T02:09:43","guid":{"rendered":"https:\/\/nebula.org\/blog\/%d8%b9%d9%84%d9%85-%d9%88%d8%b1%d8%a7%d8%ab%d8%a9-%d9%81%d9%82%d8%b1-%d8%a7%d9%84%d8%af%d9%85-%d9%88%d8%ad%d8%b4%d9%8a-2020\/"},"modified":"2021-02-20T21:09:45","modified_gmt":"2021-02-21T02:09:45","slug":"%d8%b9%d9%84%d9%85-%d9%88%d8%b1%d8%a7%d8%ab%d8%a9-%d9%81%d9%82%d8%b1-%d8%a7%d9%84%d8%af%d9%85-%d9%88%d8%ad%d8%b4%d9%8a-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/ar\/%d8%b9%d9%84%d9%85-%d9%88%d8%b1%d8%a7%d8%ab%d8%a9-%d9%81%d9%82%d8%b1-%d8%a7%d9%84%d8%af%d9%85-%d9%88%d8%ad%d8%b4%d9%8a-2020\/","title":{"rendered":"\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (Savage \u060c 2020)"},"content":{"rendered":"\n<p><strong>\u0639\u0646\u0648\u0627\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629:<\/strong><a rel=\"noreferrer noopener\" href=\"https:\/\/www.cell.com\/ajhg\/fulltext\/S0002-9297(20)30004-5\" target=\"_blank\"> \u062a\u062d\u062f\u062f \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0631\u0627\u0628\u0637\u0629 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062c\u064a\u0646\u0648\u0645 HLA-DPB1 \u0643\u0639\u0627\u0645\u0644 \u062e\u0637\u0631 \u0645\u0647\u0645 \u0644\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a \u0627\u0644\u0634\u062f\u064a\u062f<\/a><\/p>\n\n<p><strong>\u0645\u0644\u062e\u0635:<\/strong> \u062a\u062d\u062f\u064a\u062f \u0645\u0646\u0637\u0642\u062a\u064a\u0646 \u062c\u064a\u0646\u0648\u0645\u064a\u062a\u064a\u0646 \u0645\u0631\u062a\u0628\u0637\u062a\u064a\u0646 \u0628\u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a \u0627\u0644\u062d\u0627\u062f.<\/p>\n\n<p><strong>\u0646\u0638\u0631\u0629 \u0639\u0627\u0645\u0629:<\/strong> \u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (AA) \u0647\u0648 \u0623\u062d\u062f \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0630\u0627\u062a\u064a\u0629 \u062d\u064a\u062b \u0644\u0627 \u064a\u0646\u062a\u062c \u0646\u062e\u0627\u0639 \u0627\u0644\u0639\u0638\u0645 \u0645\u0627 \u064a\u0643\u0641\u064a \u0645\u0646 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645. \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0634\u062f\u064a\u062f\u0629 \u060c \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0635\u0628\u062d AA \u0645\u0647\u062f\u062f\u0629 \u0644\u0644\u062d\u064a\u0627\u0629. \u0633\u0639\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062c\u064a\u0646\u0648\u0645 \u0625\u0644\u0649 \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a \u0627\u0644\u062d\u0627\u062f \u0645\u0646 \u062e\u0644\u0627\u0644 \u0641\u062d\u0635 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 \u0644\u0645\u0627 \u064a\u0642\u0631\u0628 \u0645\u0646 3000 \u0641\u0631\u062f \u0645\u0646 \u0623\u0635\u0644 \u0623\u0648\u0631\u0648\u0628\u064a. \u0623\u0634\u0627\u0631\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0625\u0644\u0649 \u0648\u062c\u0648\u062f \u0645\u0646\u0637\u0642\u062a\u064a\u0646 \u0648\u0631\u0627\u062b\u064a\u062a\u064a\u0646 \u0645\u0631\u062a\u0628\u0637\u062a\u064a\u0646 \u0628\u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u062a\u0645\u062f\u062f \u0627\u0644\u0634\u062f\u064a\u062f. \u062a\u0631\u0645\u064a\u0632 \u0643\u0644\u0627 \u0627\u0644\u0645\u0646\u0637\u0642\u062a\u064a\u0646 \u0627\u0644\u062c\u064a\u0646\u064a\u062a\u064a\u0646 \u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0646\u0638\u0627\u0645 \u0645\u0633\u062a\u0636\u062f \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u0628\u064a\u0636 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 (HLA) \u0627\u0644\u0630\u064a \u064a\u0644\u0639\u0628 \u062f\u0648\u0631\u064b\u0627 \u0641\u064a \u062a\u0646\u0638\u064a\u0645 \u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629.<\/p>\n\n<p><strong>\u0647\u0644 \u0643\u0646\u062a \u062a\u0639\u0644\u0645\u061f<\/strong> \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0624\u062f\u064a \u0627\u0644\u062a\u0639\u0631\u0636 \u0644\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u0633\u0627\u0645\u0629 \u0645\u062b\u0644 \u0627\u0644\u0645\u0628\u064a\u062f\u0627\u062a \u0627\u0644\u062d\u0634\u0631\u064a\u0629 \u0648\u0627\u0644\u0645\u0628\u064a\u062f\u0627\u062a \u0627\u0644\u062d\u0634\u0631\u064a\u0629 \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a. \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0643\u0648\u0646 \u0627\u0644\u062d\u0627\u0644\u0629 \u0623\u064a\u0636\u064b\u0627 \u0645\u0646 \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u0645\u0624\u0642\u062a\u0629 \u0644\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0625\u0634\u0639\u0627\u0639\u064a \u0648\u0627\u0644\u0643\u064a\u0645\u0627\u0648\u064a \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645 \u0641\u064a \u0639\u0644\u0627\u062c \u0627\u0644\u0633\u0631\u0637\u0627\u0646. <a rel=\"noreferrer noopener\" href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/aplastic-anemia\/symptoms-causes\/syc-20355015\" target=\"_blank\">[SOURCE]<\/a><\/p>\n\n<p><strong>\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0639\u064a\u0646\u0629:<\/strong> \u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u0645\u0632\u064a\u062f \u062d\u0648\u0644<a href=\"https:\/\/nebula.org\/blog\/ar\/%d9%85%d9%83%d8%aa%d8%a8%d8%a9-%d8%a7%d9%84%d8%b3%d8%af%d9%8a%d9%85-%d9%81%d8%aa%d8%ad-%d9%81%d8%aa%d8%ad-%d8%a7%d9%84%d8%a8%d8%ad%d8%ab-%d8%a7%d9%84%d8%ac%d9%8a%d9%86%d9%8a\/\"> \u0645\u0643\u062a\u0628\u0629 \u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0633\u062f\u064a\u0645<\/a> . <\/p>\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\"><img decoding=\"async\" width=\"1024\" height=\"375\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png\" alt=\"&#x646;&#x62A;&#x627;&#x626;&#x62C; &#x639;&#x64A;&#x646;&#x629; &#x641;&#x642;&#x631; &#x627;&#x644;&#x62F;&#x645; &#x627;&#x644;&#x644;&#x627;&#x62A;&#x646;&#x633;&#x62C;&#x64A;\" class=\"wp-image-1066\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png 1024w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-300x110.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-768x281.png 768w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1536x562.png 1536w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics.png 924w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n<p><\/p>\n\n<p><strong>\u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0645\u062d\u0644\u0644\u0629:<\/strong> rs1042151 \u060c rs28367832<\/p>\n\n<p><strong>\u0645\u0635\u0627\u062f\u0631 \u0625\u0636\u0627\u0641\u064a\u0629:<\/strong><br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/www.nhlbi.nih.gov\/health-topics\/aplastic-anemia\" target=\"_blank\">\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a<\/a><br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/www.youtube.com\/watch?v=w8-jx1dtg0U\" target=\"_blank\">\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (\u0641\u064a\u062f\u064a\u0648)<\/a><\/p>\n\n<p><strong>\u062a\u062d\u062f\u064a\u062b \u0627\u0633\u0628\u0648\u0639\u064a:<\/strong> 15 \u0641\u0628\u0631\u0627\u064a\u0631 2020<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0639\u0646\u0648\u0627\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629: \u062a\u062d\u062f\u062f \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0631\u0627\u0628\u0637\u0629 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062c\u064a\u0646\u0648\u0645 HLA-DPB1 \u0643\u0639\u0627\u0645\u0644 \u062e\u0637\u0631 \u0645\u0647\u0645 \u0644\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a \u0627\u0644\u0634\u062f\u064a\u062f \u0645\u0644\u062e\u0635: \u062a\u062d\u062f\u064a\u062f \u0645\u0646\u0637\u0642\u062a\u064a\u0646 \u062c\u064a\u0646\u0648\u0645\u064a\u062a\u064a\u0646 \u0645\u0631\u062a\u0628\u0637\u062a\u064a\u0646 \u0628\u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a \u0627\u0644\u062d\u0627\u062f. \u0646\u0638\u0631\u0629 \u0639\u0627\u0645\u0629: \u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (AA) \u0647\u0648 \u0623\u062d\u062f \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0630\u0627\u062a\u064a\u0629 \u062d\u064a\u062b \u0644\u0627 &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/ar\/%d8%b9%d9%84%d9%85-%d9%88%d8%b1%d8%a7%d8%ab%d8%a9-%d9%81%d9%82%d8%b1-%d8%a7%d9%84%d8%af%d9%85-%d9%88%d8%ad%d8%b4%d9%8a-2020\/\"> <span class=\"screen-reader-text\">\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (Savage \u060c 2020)<\/span> \u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":16039,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[5050],"tags":[],"class_list":["post-16035","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-5050"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.13 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u0639\u0644\u0645 \u0627\u0644\u0648\u0631\u0627\u062b\u0629 \u0645\u0646 \u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (\u0633\u0627\u0641\u0627\u062c \u060c 2020)<\/title>\n<meta name=\"description\" content=\"\u0642\u0645 \u0628\u062a\u062d\u0645\u064a\u0644 \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0643 \u060c \u0648\u0627\u0633\u062a\u0643\u0634\u0641 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0644\u0627\u062a\u0646\u0633\u062c\u064a (Savage \u060c 2020) \u060c \u0648\u0627\u0643\u062a\u0634\u0641 \u0646\u0642\u0627\u0637\u0643 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