{"id":10057,"date":"2021-01-06T00:06:25","date_gmt":"2021-01-06T05:06:25","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-gehirns-laesionen-armstrong-2020\/"},"modified":"2021-02-20T20:30:02","modified_gmt":"2021-02-21T01:30:02","slug":"genetik-des-gehirns-laesionen-armstrong-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-gehirns-laesionen-armstrong-2020\/","title":{"rendered":"Hirnl\u00e4sionen (Armstrong, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> H\u00e4ufige genetische Variationen weisen auf unterschiedliche Ursachen f\u00fcr Hyperintensit\u00e4ten der periventrikul\u00e4ren und tiefwei\u00dfen Materie hin<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Entdeckung von 11 Genomregionen, die mit Hyperintensit\u00e4ten der periventrikul\u00e4ren wei\u00dfen Substanz assoziiert sind und auf Hirnl\u00e4sionen hinweisen.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Das Gehirn ist ein empfindliches Organ, das eine konstante Durchblutung erfordert. Schlaganf\u00e4lle treten auf, wenn ein gro\u00dfer Teil des Gehirns aufgrund eines starken Gerinnsels oder einer Blutung nicht mehr mit Blut versorgt wird – dies f\u00fchrt zu offensichtlichen Hirnsch\u00e4den. Kleinere Blutgerinnsel oder Blutungen k\u00f6nnen jedoch Gehirnzellen t\u00f6ten oder sch\u00e4digen und m\u00f6glicherweise Demenz oder Bewegungsprobleme verursachen. Diese k\u00f6nnen unentdeckt bleiben, bis der Patient einen Gehirn-Scan erh\u00e4lt: Der Schaden zeigt sich als hellerer wei\u00dfer Fleck, der als Hyperintensit\u00e4t bezeichnet wird. Diese Studie suchte nach diesen wei\u00dfen Flecken in Gehirnscans in der N\u00e4he der Fl\u00fcssigkeitss\u00e4cke im Zentrum des Gehirns, die als Ventrikel bezeichnet werden. Diese Hirnl\u00e4sionen werden als periventrikul\u00e4re Hyperintensit\u00e4ten der wei\u00dfen Substanz bezeichnet. Bei der Untersuchung von Gehirnscans von \u00fcber 26.000 Menschen identifizierten die Autoren 11 Genomregionen, die mit Hyperintensit\u00e4ten der periventrikul\u00e4ren wei\u00dfen Substanz assoziiert sind. Das Vorhandensein dieser L\u00e4sionen war mit einem erh\u00f6hten Schlaganfallrisiko verbunden, jedoch nicht mit einem erh\u00f6hten Demenzrisiko.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Es gibt Hinweise darauf, dass L\u00e4sionen der wei\u00dfen Substanz vermeidbar sein k\u00f6nnen, wenn man nicht raucht und Bluthochdruck, Typ-2-Diabetes und Fettleibigkeit verhindert. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

BRAIN LESION-ASSOZIIERTE VARIANTEN:<\/strong> Rs3744020, Rs3758575, Rs12928520, Rs275350, Rs7596872, Rs72934583, Rs57242328, Rs7213273, Rs1993484, Rs11838776, Rs1799983 <\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Was ist eine Krankheit der wei\u00dfen Substanz? (Video)<\/a>Krankheit der wei\u00dfen Substanz<\/a><\/p>\n\n

SIE K\u00d6NNEN AUCH INTERESSIERT SEIN an:<\/strong> Schlaganfall (Malik, 2018)<\/a>Dicke der Hirnrinde (Grasby, 2020)<\/a>Gesamthirnvolumen (Zhao, 2019)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 25. Juni 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: H\u00e4ufige genetische Variationen weisen auf unterschiedliche Ursachen f\u00fcr Hyperintensit\u00e4ten der periventrikul\u00e4ren und tiefwei\u00dfen Materie hin ZUSAMMENFASSUNG: Entdeckung von 11 Genomregionen, die mit Hyperintensit\u00e4ten der periventrikul\u00e4ren wei\u00dfen Substanz assoziiert sind und auf Hirnl\u00e4sionen hinweisen. \u00dcBERBLICK: Das Gehirn ist ein empfindliches …<\/p>\n

Hirnl\u00e4sionen (Armstrong, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6566,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10057","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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