{"id":10140,"date":"2021-01-06T00:08:17","date_gmt":"2021-01-06T05:08:17","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-plattenepithel-lungen-karzinom-mckay-2017\/"},"modified":"2021-02-20T20:23:14","modified_gmt":"2021-02-21T01:23:14","slug":"genetik-plattenepithel-lungen-karzinom-mckay-2017","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-plattenepithel-lungen-karzinom-mckay-2017\/","title":{"rendered":"Plattenepithelkarzinom (McKay, 2017)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Eine gro\u00df angelegte Assoziationsanalyse identifiziert neue Anf\u00e4lligkeitsorte f\u00fcr Lungenkrebs und Heterogenit\u00e4t der genetischen Anf\u00e4lligkeit \u00fcber histologische Subtypen hinweg<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 3 Genomregionen, die mit Plattenepithelkarzinomen assoziiert sind. <\/p>\n\n

\u00dcBERBLICK:<\/strong> Lungenkrebs ist eine Erkrankung, bei der sich Zellen in der Lunge unkontrolliert teilen. Plattenepithelzellen sind flach geformte Zellen, die viele Organe im K\u00f6rper auskleiden. Das Plattenepithelkarzinom (SCLC) ist eine Art von Lungenkrebs, der durch Mutationen in Plattenepithelkarzinomen verursacht wird, die die Atemwege der Lunge auskleiden. Dieser Lungenkrebs-Subtyp macht 30% aller Lungenkrebsf\u00e4lle aus und ist h\u00e4ufig mit einer Vorgeschichte des Rauchens verbunden. Um die genetischen Grundlagen von SCLC zu verstehen, untersuchten die Forscher die Genome von ~ 63.000 Individuen. Sie identifizierten 3 mit SCLC assoziierte Genomregionen. Insgesamt erkl\u00e4ren diese genetischen Varianten ungef\u00e4hr 6,2% der Heritabilit\u00e4t von SCLC. <\/p>\n\n

HAST DU GEWUSST?<\/strong> Die h\u00e4ufigste Art von Lungenkrebs bei M\u00e4nnern ist das Plattenepithelkarzinom. Dieser Subtyp von Lungenkrebs ist oft leichter zu erkennen, da er mehr Symptome hervorruft als andere Subtypen von Lungenkrebs. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

SCLC-assoziierte Varianten:<\/strong> rs116822326, rs17879961, rs7953330<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Lungenkrebs (Video)<\/a>Lungenkrebsarten<\/a>Plattenepithelkarzinom der Lunge<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 12. Mai 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Eine gro\u00df angelegte Assoziationsanalyse identifiziert neue Anf\u00e4lligkeitsorte f\u00fcr Lungenkrebs und Heterogenit\u00e4t der genetischen Anf\u00e4lligkeit \u00fcber histologische Subtypen hinweg ZUSAMMENFASSUNG: Identifizierung von 3 Genomregionen, die mit Plattenepithelkarzinomen assoziiert sind. \u00dcBERBLICK: Lungenkrebs ist eine Erkrankung, bei der sich Zellen in der …<\/p>\n

Plattenepithelkarzinom (McKay, 2017)<\/span> Read More 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Genetik des Plattenepithelkarzinoms (McKay, 2017)<\/title>\n<meta name=\"description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Plattenepithelkarzinomen (McKay, 2017) und ermitteln Sie Ihren polygenen Score.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-plattenepithel-lungen-karzinom-mckay-2017\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Die Genetik des Plattenepithelkarzinoms (McKay, 2017)\" \/>\n<meta property=\"og:description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Plattenepithelkarzinomen (McKay, 2017) und ermitteln Sie Ihren polygenen Score.\" \/>\n<meta property=\"og:url\" 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