{"id":10235,"date":"2021-01-06T00:11:50","date_gmt":"2021-01-06T05:11:50","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-long-qt-syndrom-lahrouchi-2020\/"},"modified":"2021-02-20T20:23:44","modified_gmt":"2021-02-21T01:23:44","slug":"genetik-long-qt-syndrom-lahrouchi-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-long-qt-syndrom-lahrouchi-2020\/","title":{"rendered":"Langes QT-Syndrom (Lahrouchi, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Die transethnische genomweite Assoziationsstudie liefert Einblicke in die genetische Architektur und Heritabilit\u00e4t des Long-QT-Syndroms<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 3 Genomregionen, die mit dem Long-QT-Syndrom assoziiert sind.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Der Herzschlag wird durch elektrische Impulse gesteuert, die normalerweise zwischen den Schl\u00e4gen pausieren. W\u00e4hrend dieser Pause laden sich die Herzmuskeln f\u00fcr den n\u00e4chsten Schlag auf. Wenn dieses Aufladen zu lange dauert, zeigt ein Elektrokardiogramm ein langes QT-Intervall. Menschen mit langen QT-Intervallen k\u00f6nnen von einem schnellen und chaotischen Herzschlag betroffen sein, der Ohnmacht, Krampfanf\u00e4lle und sogar den Tod verursachen kann. Diese Studie verglich 1.656 europ\u00e4ische oder japanische Personen mit langem QT-Syndrom mit 9.890 gesunden Kontrollen und fand drei assoziierte Genomregionen.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Einige Medikamente k\u00f6nnen dieses Syndrom verursachen. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

LANGE QT-ASSOZIIERTE VARIANTEN:<\/strong> rs12143842, rs179405, rs17061696<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Was ist das lange QT-Syndrom? (Video)<\/a>Grundlage f\u00fcr genetische Unterst\u00fctzung: Long QT-Syndrom<\/a><\/p>\n\n

SIE K\u00d6NNEN AUCH INTERESSIERT SEIN an:<\/strong> Herzinsuffizienz (Shah, 2020)<\/a>PR-Intervall (Ntalla, 2020)<\/a>QT-Intervall (Arking, 2014)<\/a>Schlagvolumen (Pirruccello, 2020)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 16. Juni 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Die transethnische genomweite Assoziationsstudie liefert Einblicke in die genetische Architektur und Heritabilit\u00e4t des Long-QT-Syndroms ZUSAMMENFASSUNG: Identifizierung von 3 Genomregionen, die mit dem Long-QT-Syndrom assoziiert sind. \u00dcBERBLICK: Der Herzschlag wird durch elektrische Impulse gesteuert, die normalerweise zwischen den Schl\u00e4gen pausieren. …<\/p>\n

Langes QT-Syndrom (Lahrouchi, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6501,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10235","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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