{"id":10238,"date":"2021-01-06T00:11:52","date_gmt":"2021-01-06T05:11:52","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-duennheit-orthofer-2020\/"},"modified":"2021-02-20T20:20:03","modified_gmt":"2021-02-21T01:20:03","slug":"genetik-duennheit-orthofer-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-duennheit-orthofer-2020\/","title":{"rendered":"D\u00fcnnheit (Orthofer, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Identifizierung von ALK in D\u00fcnnheit<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Entdeckung von 5 genetischen Varianten im Zusammenhang mit D\u00fcnnheit.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Obwohl Ern\u00e4hrung und Bewegung wichtig sind, um ein gesundes K\u00f6rpergewicht aufrechtzuerhalten, k\u00f6nnen Personen, die \u00e4hnliche Lebensmittel essen und \u00e4hnliche Mengen trainieren, sich in ihrem Gewicht unterscheiden. Die meisten Studien, die nach genetischen Varianten suchen, die mit dem Body Mass Index (BMI) assoziiert sind, vergleichen adip\u00f6se Personen mit gesunden Kontrollen. Diese Studie suchte stattdessen nach Assoziationen mit D\u00fcnnheit. Die Forscher verglichen die d\u00fcnnsten 1,9% der Personen (6. BMI-Perzentil; 881 Personen) in der estnischen Biobank mit Personen mit einem durchschnittlichen K\u00f6rpergewicht (30. – 50. BMI-Perzentil; 3.173 Personen) und fanden 5 Varianten, die mit D\u00fcnnheit assoziiert sind. Eine der Varianten (rs568057364) befindet sich im ALK-Gen, von dem bekannt ist, dass es bei Krebs eine Rolle spielt. Die Forscher st\u00f6rten das ALK-Gen bei M\u00e4usen und stellten fest, dass es zu einer Resistenz gegen di\u00e4tbedingte Fettleibigkeit f\u00fchrte.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Untergewichtige Menschen leiden h\u00e4ufig unter N\u00e4hrstoffmangel, weil sie nicht genug Nahrung zu sich nehmen, um alle Vitamine und Mineralien zu erhalten, die ihr K\u00f6rper ben\u00f6tigt. Es ist wichtig, gen\u00fcgend Mikron\u00e4hrstoffe zu sich zu nehmen, auch wenn die Kalorienaufnahme begrenzt ist. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

D\u00dcNNIGKEITSVERBUNDENE VARIANTEN:<\/strong> rs6574213, rs79938778, rs61685635, rs568057364, rs4521442<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Gewichtsverlust und Body Mass Index (Video)<\/a>BMI-Rechner<\/a><\/p>\n\n

SIE K\u00d6NNEN AUCH INTERESSIERT SEIN an:<\/strong> Geburtsgewicht und Krankheitsanf\u00e4lligkeit (Horikoshi, 2017)<\/a>Body Mass Index (Couto Alves, 2019)<\/a>Body Mass Index (Anderson, 2020)<\/a>Fettleibigkeit (Jiao, 2011)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 16. Juni 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Identifizierung von ALK in D\u00fcnnheit ZUSAMMENFASSUNG: Entdeckung von 5 genetischen Varianten im Zusammenhang mit D\u00fcnnheit. \u00dcBERBLICK: Obwohl Ern\u00e4hrung und Bewegung wichtig sind, um ein gesundes K\u00f6rpergewicht aufrechtzuerhalten, k\u00f6nnen Personen, die \u00e4hnliche Lebensmittel essen und \u00e4hnliche Mengen trainieren, sich in …<\/p>\n

D\u00fcnnheit (Orthofer, 2020)<\/span> Read More 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