{"id":10261,"date":"2021-01-06T00:12:30","date_gmt":"2021-01-06T05:12:30","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-tourettes-syndroms-yu-2019\/"},"modified":"2021-02-20T20:34:18","modified_gmt":"2021-02-21T01:34:18","slug":"genetik-des-tourettes-syndroms-yu-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-tourettes-syndroms-yu-2019\/","title":{"rendered":"Tourette-Syndrom (Yu, 2019)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Befragung der genetischen Determinanten des Tourette-Syndroms und anderer Tic-St\u00f6rungen durch genomweite Assoziationsstudien<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Entdeckung mehrerer genetischer Varianten im Zusammenhang mit dem Tourette-Syndrom.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Das Tourette-Syndrom ist eine St\u00f6rung des Nervensystems, die durch unkontrollierbare Bewegungen oder Ger\u00e4usche gekennzeichnet ist, die als Tics bezeichnet werden. Es betrifft etwa 1 von 150 Menschen in unterschiedlichem Ma\u00dfe. Das Tourette-Syndrom ist als hoch vererbbar bekannt, wobei bis zu 80% des Krankheitsrisikos von den Eltern vererbt werden. Diese genomweite Assoziationsstudie versuchte, genetische Varianten im Zusammenhang mit dem Tourette-Syndrom zu identifizieren, indem \u00fcber 20.000 Personen europ\u00e4ischer Abstammung untersucht wurden. Eine der Top-Varianten befindet sich im FLT3-Gen, das ein Rezeptorprotein codiert, von dem angenommen wird, dass es eine Rolle bei den Funktionen des Immunsystems spielt. Die Autoren berichten auch \u00fcber 9 andere genetische Varianten, die signifikant mit dem Tourette-Syndrom assoziiert sind.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Das Tourette-Syndrom wird normalerweise fr\u00fch im Leben diagnostiziert. Obwohl es sich um eine chronische Erkrankung handelt, erleben viele Betroffene in den Teenagerjahren einen H\u00f6hepunkt der Symptome, gefolgt von einer allm\u00e4hlichen Besserung im Erwachsenenalter. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Probenergebnisse<\/a><\/figure>\n\n

TOURETTE’S ASSOZIIERTE VARIANTEN:<\/strong> Rs2504235, Rs191044310, Rs13407215, Rs2708146, Rs1906252, Rs12459560, Rs117648881, Rs6670211, Rs72853320, Rs73205493<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Tourette-Syndrom: Was macht Menschen nerv\u00f6s? (Video)<\/a>Was ist Tourette?<\/a><\/p>\n\n

SIE K\u00d6NNEN AUCH INTERESSIERT SEIN an:<\/strong> Zittern (M\u00fcller, 2016)<\/a>Epilepsie (ILAEC, 2014)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 11. Juli 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Befragung der genetischen Determinanten des Tourette-Syndroms und anderer Tic-St\u00f6rungen durch genomweite Assoziationsstudien ZUSAMMENFASSUNG: Entdeckung mehrerer genetischer Varianten im Zusammenhang mit dem Tourette-Syndrom. \u00dcBERBLICK: Das Tourette-Syndrom ist eine St\u00f6rung des Nervensystems, die durch unkontrollierbare Bewegungen oder Ger\u00e4usche gekennzeichnet ist, die …<\/p>\n

Tourette-Syndrom (Yu, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6626,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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