{"id":10398,"date":"2021-01-06T00:27:30","date_gmt":"2021-01-06T05:27:30","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-der-kawasaki-krankheit-onouchi-2012\/"},"modified":"2021-02-20T20:45:01","modified_gmt":"2021-02-21T01:45:01","slug":"genetik-der-kawasaki-krankheit-onouchi-2012","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-der-kawasaki-krankheit-onouchi-2012\/","title":{"rendered":"Kawasaki-Krankheit (Onouchi, 2012)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Eine genomweite Assoziationsstudie identifiziert drei neue Risikostandorte f\u00fcr die Kawasaki-Krankheit<\/a> <\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 3 genetischen Varianten im Zusammenhang mit der Kawasaki-Krankheit, die eine Entz\u00fcndung und Schwellung der Blutgef\u00e4\u00dfe verursacht.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Die Kawasaki-Krankheit ist durch eine pl\u00f6tzliche Entz\u00fcndung und Schwellung der Blutgef\u00e4\u00dfe im gesamten K\u00f6rper gekennzeichnet, die typischerweise mehrere Tage anh\u00e4lt. Es betrifft haupts\u00e4chlich Kinder unter 5 Jahren, es wurden jedoch auch F\u00e4lle der Krankheit bei Erwachsenen beschrieben. Ein typisches Symptom der Krankheit ist R\u00f6tung, die verschiedene K\u00f6rperteile wie Augen, Zunge und Haut betrifft. Die Kawasaki-Krankheit ist in Teilen Ostasiens, insbesondere in Japan, h\u00e4ufig. Bei der Untersuchung von fast 4.000 Kindern japanischer Abstammung wurden in dieser genomweiten Assoziationsstudie drei genetische Varianten identifiziert, die mit der Krankheit assoziiert sind. Zwei dieser genetischen Varianten befinden sich in genomischen Regionen, die zuvor mit Autoimmunerkrankungen wie rheumatoider Arthritis und systemischem Lupus erythematodes assoziiert waren.<\/p>\n\n

HAST DU GEWUSST?<\/strong> F\u00fcr Kinder in den Vereinigten Staaten ist die Kawasaki-Krankheit die h\u00e4ufigste Ursache f\u00fcr erworbene Herzkrankheiten. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

KAWASAKI-KRANKHEITSVERBUNDENE VARIANTEN:<\/strong> rs2254546, rs2857151, rs4813003<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Was ist die Kawasaki-Krankheit?<\/a> (Video)Kawasaki-Krankheit <\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 23. Januar 2020<\/p>\n\n

<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Eine genomweite Assoziationsstudie identifiziert drei neue Risikostandorte f\u00fcr die Kawasaki-Krankheit ZUSAMMENFASSUNG: Identifizierung von 3 genetischen Varianten im Zusammenhang mit der Kawasaki-Krankheit, die eine Entz\u00fcndung und Schwellung der Blutgef\u00e4\u00dfe verursacht. \u00dcBERBLICK: Die Kawasaki-Krankheit ist durch eine pl\u00f6tzliche Entz\u00fcndung und Schwellung …<\/p>\n

Kawasaki-Krankheit (Onouchi, 2012)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5171,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10398","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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