{"id":10479,"date":"2021-01-06T00:29:02","date_gmt":"2021-01-06T05:29:02","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-von-ptsd-lerner-2019\/"},"modified":"2021-02-20T20:36:14","modified_gmt":"2021-02-21T01:36:14","slug":"genetik-von-ptsd-lerner-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-von-ptsd-lerner-2019\/","title":{"rendered":"PTBS (Gelernter, 2019)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Genomweite Assoziationsstudie zur posttraumatischen Belastungsst\u00f6rung, bei der Symptome in erneut auftreten> 165.000 US-Veteranen<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Diese Studie identifizierte acht neue Loci, die mit dem Wiederauftreten eines Traumas einer posttraumatischen Belastungsst\u00f6rung (PTBS) assoziiert sind.<\/p>\n\n

BESCHREIBUNG:<\/strong> Posttraumatische Belastungsst\u00f6rung (PTBS) ist eine psychiatrische St\u00f6rung, die auftreten kann, wenn Personen ein traumatisches Ereignis wie eine Naturkatastrophe, einen schweren Unfall oder Gewalt erleben oder erleben. Das Wiedererleben des Traumas ist das charakteristischste Symptom der PTBS. W\u00e4hrend viele Faktoren die Entwicklung von PTBS beeinflussen, k\u00f6nnen genetische Varianten zu einer erh\u00f6hten Veranlagung f\u00fcr die Entwicklung der St\u00f6rung f\u00fchren. Um m\u00f6gliche genetische Risikofaktoren f\u00fcr das Wiederauftreten eines Traumas zu identifizieren, untersuchte diese genomweite Assoziationsstudie 164.643 afroamerikanische und europ\u00e4isch-amerikanische Veteranen. Es wurde festgestellt, dass acht Varianten mit dem erneuten Erleben eines PTBS-Traumas zusammenh\u00e4ngen, was weniger als 1 \\ u0025 der Erblichkeit erkl\u00e4rt. Regionen in der N\u00e4he der CAMKV-, KANSL1- und TCF4-Gene waren besonders signifikant. CAMKV war zuvor mit dem Bildungsabschluss verbunden, und TCF4 ist bekannterma\u00dfen mit Schizophrenie verbunden.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Es gibt verschiedene psychiatrische Therapien, die bei der Behandlung von PTBS helfen k\u00f6nnen. Bei den meisten Therapien muss sich der Patient mit dem Trauma auseinandersetzen und es diskutieren. Medikamente wie Antidepressiva werden ebenfalls verschrieben. [ QUELLE<\/a> ]]<\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> .<\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

PTSD-ASSOZIIERTE VARIANTEN:<\/strong> rs2777888, rs2123392, rs2532252, rs7519147, rs10235664, rs4697248, rs7688962, rs67529088<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong> Symptome von PTBS<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 9. August 2019<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Genomweite Assoziationsstudie zur posttraumatischen Belastungsst\u00f6rung, bei der Symptome in erneut auftreten> 165.000 US-Veteranen ZUSAMMENFASSUNG: Diese Studie identifizierte acht neue Loci, die mit dem Wiederauftreten eines Traumas einer posttraumatischen Belastungsst\u00f6rung (PTBS) assoziiert sind. BESCHREIBUNG: Posttraumatische Belastungsst\u00f6rung (PTBS) ist eine psychiatrische …<\/p>\n

PTBS (Gelernter, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5381,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10479","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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