{"id":10495,"date":"2021-01-06T00:29:18","date_gmt":"2021-01-06T05:29:18","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-der-sepsis-guillen-guio-2020\/"},"modified":"2021-02-20T20:40:05","modified_gmt":"2021-02-21T01:40:05","slug":"genetik-der-sepsis-guillen-guio-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/","title":{"rendered":"Atemnotsyndrom (Guillen-Guio, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Sepsis-assoziiertes akutes Atemnotsyndrom bei Personen europ\u00e4ischer Abstammung: eine genomweite Assoziationsstudie<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Entdeckung einer Variante im FTL1-Gen, die mit der Anf\u00e4lligkeit f\u00fcr Sepsis-induziertes akutes Atemnotsyndrom assoziiert ist.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Sepsis tritt auf, wenn Chemikalien, die im Blutkreislauf freigesetzt werden, um eine Infektion zu bek\u00e4mpfen, Entz\u00fcndungen im ganzen K\u00f6rper ausl\u00f6sen. Sepsis kann lebensbedrohlich sein und zu einer langfristigen Sch\u00e4digung vieler Organe f\u00fchren. Wenn die Lunge betroffen ist, kann dies zu einem akuten Atemnotsyndrom (ARDS) f\u00fchren, bei dem Fl\u00fcssigkeiten in die Lunge gelangen und das Atmen extrem erschweren. Personen, die ARDS \u00fcberleben, leiden h\u00e4ufig unter dauerhaften kognitiven und k\u00f6rperlichen Beeintr\u00e4chtigungen, die durch Organsch\u00e4den aufgrund unzureichender Sauerstoffversorgung verursacht werden. Diese genomweite Studie untersuchte fast 2.000 Personen europ\u00e4ischer Abstammung, um die genetische Veranlagung zur Entwicklung von ARDS bei Patienten mit Sepsis besser zu verstehen. Die Studie entdeckte eine Variante des FTL1-Gens. FTL1 codiert a Rezeptor<\/em> Das spielt eine wichtige Rolle bei der Entwicklung und Funktion des K\u00f6rpergef\u00e4\u00dfsystems.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Sch\u00e4tzungen zufolge sind jedes Jahr fast 30 Millionen Menschen von Sepsis betroffen. Zu den gef\u00e4hrdeten Bev\u00f6lkerungsgruppen z\u00e4hlen \u00e4ltere Menschen, schwangere Frauen und Krankenhauspatienten. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Sepsis-Probenergebnisse\"<\/a><\/figure>\n\n

<\/p>\n\n

ANALYSIERTE VARIANTEN:<\/strong> rs9508032<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Was ist Sepsis? (Video)<\/a>Akutes Lungenversagen<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 31. Januar 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Sepsis-assoziiertes akutes Atemnotsyndrom bei Personen europ\u00e4ischer Abstammung: eine genomweite Assoziationsstudie ZUSAMMENFASSUNG: Entdeckung einer Variante im FTL1-Gen, die mit der Anf\u00e4lligkeit f\u00fcr Sepsis-induziertes akutes Atemnotsyndrom assoziiert ist. \u00dcBERBLICK: Sepsis tritt auf, wenn Chemikalien, die im Blutkreislauf freigesetzt werden, um eine …<\/p>\n

Atemnotsyndrom (Guillen-Guio, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5406,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10495","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie Genetik der Sepsis (Guillen-Guio, 2020)<\/title>\n<meta name=\"description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Sepsis (Guillen-Guio, 2020) und entdecken Sie Ihren polygenen Score.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Die Genetik der Sepsis (Guillen-Guio, 2020)\" \/>\n<meta property=\"og:description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Sepsis (Guillen-Guio, 2020) und entdecken Sie Ihren polygenen Score.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-06T05:29:18+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-02-21T01:40:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/robina-weermeijer-Pw9aFhc92P8-unsplash-1-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"924\" \/>\n\t<meta property=\"og:image:height\" content=\"520\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"1\u00a0Minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Atemnotsyndrom (Guillen-Guio, 2020)\",\"datePublished\":\"2021-01-06T05:29:18+00:00\",\"dateModified\":\"2021-02-21T01:40:05+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\"},\"wordCount\":228,\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#organization\"},\"articleSection\":[\"Berichte\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\",\"url\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\",\"name\":\"Die Genetik der Sepsis (Guillen-Guio, 2020)\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#website\"},\"datePublished\":\"2021-01-06T05:29:18+00:00\",\"dateModified\":\"2021-02-21T01:40:05+00:00\",\"description\":\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Sepsis (Guillen-Guio, 2020) und entdecken Sie Ihren polygenen Score.\",\"breadcrumb\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nebula.org\/blog\/de\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Atemnotsyndrom (Guillen-Guio, 2020)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#website\",\"url\":\"https:\/\/nebula.org\/blog\/de\/\",\"name\":\"Nebula Genomics Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nebula.org\/blog\/de\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#organization\",\"name\":\"Nebula Genomics\",\"url\":\"https:\/\/nebula.org\/blog\/de\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Nebula Genomics\"},\"image\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/facebook.com\/nebulagenomics\",\"https:\/\/twitter.com\/nebulagenomics\",\"https:\/\/www.instagram.com\/nebulagenomics\/\",\"https:\/\/www.linkedin.com\/company\/nebula-genomics\/\",\"https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\",\"name\":\"Garrett Dunlap, B.S.\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"caption\":\"Garrett Dunlap, B.S.\"},\"description\":\"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.\",\"sameAs\":[\"https:\/\/nebula.org\/whole-genome-sequencing\/\"],\"url\":\"https:\/\/nebula.org\/blog\/de\/author\/garrett-dunlap\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Die Genetik der Sepsis (Guillen-Guio, 2020)","description":"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Sepsis (Guillen-Guio, 2020) und entdecken Sie Ihren polygenen Score.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/","og_locale":"de_DE","og_type":"article","og_title":"Die Genetik der Sepsis (Guillen-Guio, 2020)","og_description":"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Sepsis (Guillen-Guio, 2020) und entdecken Sie Ihren polygenen Score.","og_url":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/","og_site_name":"Nebula Genomics Blog","article_publisher":"https:\/\/facebook.com\/nebulagenomics","article_published_time":"2021-01-06T05:29:18+00:00","article_modified_time":"2021-02-21T01:40:05+00:00","og_image":[{"width":924,"height":520,"url":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/robina-weermeijer-Pw9aFhc92P8-unsplash-1-scaled.jpg","type":"image\/jpeg"}],"author":"Garrett Dunlap, B.S.","twitter_card":"summary_large_image","twitter_creator":"@nebulagenomics","twitter_site":"@nebulagenomics","twitter_misc":{"Verfasst von":"Garrett Dunlap, B.S.","Gesch\u00e4tzte Lesezeit":"1\u00a0Minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/#article","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/"},"author":{"name":"Garrett Dunlap, B.S.","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e"},"headline":"Atemnotsyndrom (Guillen-Guio, 2020)","datePublished":"2021-01-06T05:29:18+00:00","dateModified":"2021-02-21T01:40:05+00:00","mainEntityOfPage":{"@id":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/"},"wordCount":228,"publisher":{"@id":"https:\/\/nebula.org\/blog\/de\/#organization"},"articleSection":["Berichte"],"inLanguage":"de"},{"@type":"WebPage","@id":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/","url":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/","name":"Die Genetik der Sepsis (Guillen-Guio, 2020)","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/de\/#website"},"datePublished":"2021-01-06T05:29:18+00:00","dateModified":"2021-02-21T01:40:05+00:00","description":"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Sepsis (Guillen-Guio, 2020) und entdecken Sie Ihren polygenen Score.","breadcrumb":{"@id":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/#breadcrumb"},"inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nebula.org\/blog\/de\/genetik-der-sepsis-guillen-guio-2020\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nebula.org\/blog\/de\/"},{"@type":"ListItem","position":2,"name":"Atemnotsyndrom (Guillen-Guio, 2020)"}]},{"@type":"WebSite","@id":"https:\/\/nebula.org\/blog\/de\/#website","url":"https:\/\/nebula.org\/blog\/de\/","name":"Nebula Genomics Blog","description":"","publisher":{"@id":"https:\/\/nebula.org\/blog\/de\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nebula.org\/blog\/de\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/nebula.org\/blog\/de\/#organization","name":"Nebula Genomics","url":"https:\/\/nebula.org\/blog\/de\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Nebula Genomics"},"image":{"@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/facebook.com\/nebulagenomics","https:\/\/twitter.com\/nebulagenomics","https:\/\/www.instagram.com\/nebulagenomics\/","https:\/\/www.linkedin.com\/company\/nebula-genomics\/","https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics"]},{"@type":"Person","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e","name":"Garrett Dunlap, B.S.","image":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","caption":"Garrett Dunlap, B.S."},"description":"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/de\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts\/10495","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/comments?post=10495"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts\/10495\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/media\/5406"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/media?parent=10495"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/categories?post=10495"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/tags?post=10495"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}