{"id":10563,"date":"2021-01-06T00:30:42","date_gmt":"2021-01-06T05:30:42","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-der-prion-krankheit-met-2009\/"},"modified":"2021-02-20T20:48:45","modified_gmt":"2021-02-21T01:48:45","slug":"genetik-der-prion-krankheit-met-2009","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-der-prion-krankheit-met-2009\/","title":{"rendered":"Prion-Krankheit (Mead, 2009)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Genetische Risikofaktoren f\u00fcr die Variante der Creutzfeldt-Jakob-Krankheit: eine genomweite Assoziationsstudie<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung einer genetischen Variante, die Resistenz gegen \u00fcbertragbare Creutzfeldt-Jakob-Krankheit verleiht.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Prionkrankheiten sind Hirnst\u00f6rungen, die durch fehlgefaltete Proteine verursacht werden, die Aggregate bilden, die zu einer fortschreitenden, t\u00f6dlichen Demenz f\u00fchren. Einige Prionkrankheiten sind \u00fcbertragbar. Zum Beispiel kann der Verzehr von Fleisch, das mit falsch gefalteten Prionproteinen infiziert ist, dazu f\u00fchren, dass die k\u00f6rpereigenen Prionproteine falsch gefaltet und aggregiert werden. Diese Studie untersuchte die genetische Information von \u00fcber 5.000 Personen aus dem Vereinigten K\u00f6nigreich und Papua-Neuguinea, um die Anf\u00e4lligkeit f\u00fcr eine \u00fcbertragbare Creutzfeldt-Jakob-Krankheit (CJD) zu verstehen. Die Studie identifizierte ein variantes Allel, das Resistenz gegen eine Infektion mit dem CJD-Prionprotein verleiht. Dieses variante Allel befindet sich im menschlichen Priongen und verhindert eine induzierte Fehlfaltung und Aggregation der menschlichen Prionproteine.<\/p>\n\n

HAST DU GEWUSST?<\/strong> W\u00e4hrend Prionkrankheiten \u00e4u\u00dferst selten sind, gibt es derzeit keine Heilung. Die Ausbreitung der \u00fcbertragbaren Prionkrankheit muss durch die Zerst\u00f6rung von verdorbenem Fleisch und die ordnungsgem\u00e4\u00dfe Sterilisation medizinischer Ger\u00e4te sorgf\u00e4ltig kontrolliert werden. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

PRION-KRANKHEITSVERBUNDENE VARIANTEN:<\/strong> rs1799990<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Prionen (Video)<\/a>\u00dcbertragbare Creutzfeldt-Jakob-Krankheit<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 12. Dezember 2019<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Genetische Risikofaktoren f\u00fcr die Variante der Creutzfeldt-Jakob-Krankheit: eine genomweite Assoziationsstudie ZUSAMMENFASSUNG: Identifizierung einer genetischen Variante, die Resistenz gegen \u00fcbertragbare Creutzfeldt-Jakob-Krankheit verleiht. \u00dcBERBLICK: Prionkrankheiten sind Hirnst\u00f6rungen, die durch fehlgefaltete Proteine verursacht werden, die Aggregate bilden, die zu einer fortschreitenden, t\u00f6dlichen …<\/p>\n

Prion-Krankheit (Mead, 2009)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5331,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10563","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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