{"id":10569,"date":"2021-01-06T00:30:53","date_gmt":"2021-01-06T05:30:53","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-beschleunigten-alterns-gibson-2019\/"},"modified":"2021-01-31T11:27:18","modified_gmt":"2021-01-31T16:27:18","slug":"genetik-des-beschleunigten-alterns-gibson-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/","title":{"rendered":"Beschleunigtes Altern (Gibson, 2019)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Eine Metaanalyse genomweiter Assoziationsstudien zur epigenetischen Altersbeschleunigung<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Entdeckung von 10 genetischen Varianten im Zusammenhang mit beschleunigtem Altern.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Biologisches Alter \u201cist ein Ma\u00df daf\u00fcr, wie gut ein menschlicher K\u00f6rper im Verh\u00e4ltnis zu seinem tats\u00e4chlichen Kalenderalter funktioniert. Studien haben gezeigt, dass das biologische Alter durch Messung von DNA-Modifikationen, sogenannten Methylierungen, im gesamten Genom gesch\u00e4tzt werden kann. Das Vorhandensein dieser altersbedingten Ver\u00e4nderungen wird sowohl von Umweltfaktoren (z. B. Lebensstil) als auch von genetischen Faktoren beeinflusst. Diese genomweite Assoziationsstudie untersuchte die Genome von fast 13.500 Personen europ\u00e4ischer Abstammung und entdeckte 10 genetische Varianten, die mit DNA-Methylierungsprofilen assoziiert sind, die mit einer beschleunigten biologischen Alterung verbunden sind. Die meisten der entdeckten Varianten befinden sich in der N\u00e4he von Genen, die eine Rolle im Stoffwechsel oder im Immunsystem spielen.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Das biologische Altern kann durch gesunde Ern\u00e4hrung, regelm\u00e4\u00dfiges Training und Minimierung von Stress verlangsamt werden. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> .<\/p>\n\n

\"\"<\/a><\/figure>\n\n

<\/p>\n\n

ALTERSVERBUNDENE VARIANTEN:<\/strong> rs76244256, rs7744541, rs10778517, rs388649, rs2736099, rs1011267, rs4712953, rs6440667, rs79070372, rs62078811<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Die epigenetische Uhr (Video)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 5. Dezember 2019<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Eine Metaanalyse genomweiter Assoziationsstudien zur epigenetischen Altersbeschleunigung ZUSAMMENFASSUNG: Entdeckung von 10 genetischen Varianten im Zusammenhang mit beschleunigtem Altern. \u00dcBERBLICK: Biologisches Alter \u201cist ein Ma\u00df daf\u00fcr, wie gut ein menschlicher K\u00f6rper im Verh\u00e4ltnis zu seinem tats\u00e4chlichen Kalenderalter funktioniert. Studien haben …<\/p>\n

Beschleunigtes Altern (Gibson, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5506,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10569","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie Genetik des beschleunigten Alterns (Gibson, 2019)<\/title>\n<meta name=\"description\" content=\"Laden Sie Ihre DNA-Daten hoch, um genetische Varianten im Zusammenhang mit beschleunigtem Altern zu untersuchen (Gibson, 2019) und Ihren polygenen Score zu ermitteln.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Die Genetik des beschleunigten Alterns (Gibson, 2019)\" \/>\n<meta property=\"og:description\" content=\"Laden Sie Ihre DNA-Daten hoch, um genetische Varianten im Zusammenhang mit beschleunigtem Altern zu untersuchen (Gibson, 2019) und Ihren polygenen Score zu ermitteln.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-06T05:30:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-01-31T16:27:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2019\/12\/ravi-patel-VMGAbeeJTKo-unsplash-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"924\" \/>\n\t<meta property=\"og:image:height\" content=\"616\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"1\u00a0Minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Beschleunigtes Altern (Gibson, 2019)\",\"datePublished\":\"2021-01-06T05:30:53+00:00\",\"dateModified\":\"2021-01-31T16:27:18+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\"},\"wordCount\":187,\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#organization\"},\"articleSection\":[\"Berichte\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\",\"url\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\",\"name\":\"Die Genetik des beschleunigten Alterns (Gibson, 2019)\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#website\"},\"datePublished\":\"2021-01-06T05:30:53+00:00\",\"dateModified\":\"2021-01-31T16:27:18+00:00\",\"description\":\"Laden Sie Ihre DNA-Daten hoch, um genetische Varianten im Zusammenhang mit beschleunigtem Altern zu untersuchen (Gibson, 2019) und Ihren polygenen Score zu ermitteln.\",\"breadcrumb\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nebula.org\/blog\/de\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Beschleunigtes Altern (Gibson, 2019)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#website\",\"url\":\"https:\/\/nebula.org\/blog\/de\/\",\"name\":\"Nebula Genomics Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nebula.org\/blog\/de\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#organization\",\"name\":\"Nebula Genomics\",\"url\":\"https:\/\/nebula.org\/blog\/de\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Nebula Genomics\"},\"image\":{\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/facebook.com\/nebulagenomics\",\"https:\/\/twitter.com\/nebulagenomics\",\"https:\/\/www.instagram.com\/nebulagenomics\/\",\"https:\/\/www.linkedin.com\/company\/nebula-genomics\/\",\"https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\",\"name\":\"Garrett Dunlap, B.S.\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"caption\":\"Garrett Dunlap, B.S.\"},\"description\":\"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.\",\"sameAs\":[\"https:\/\/nebula.org\/whole-genome-sequencing\/\"],\"url\":\"https:\/\/nebula.org\/blog\/de\/author\/garrett-dunlap\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Die Genetik des beschleunigten Alterns (Gibson, 2019)","description":"Laden Sie Ihre DNA-Daten hoch, um genetische Varianten im Zusammenhang mit beschleunigtem Altern zu untersuchen (Gibson, 2019) und Ihren polygenen Score zu ermitteln.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/","og_locale":"de_DE","og_type":"article","og_title":"Die Genetik des beschleunigten Alterns (Gibson, 2019)","og_description":"Laden Sie Ihre DNA-Daten hoch, um genetische Varianten im Zusammenhang mit beschleunigtem Altern zu untersuchen (Gibson, 2019) und Ihren polygenen Score zu ermitteln.","og_url":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/","og_site_name":"Nebula Genomics Blog","article_publisher":"https:\/\/facebook.com\/nebulagenomics","article_published_time":"2021-01-06T05:30:53+00:00","article_modified_time":"2021-01-31T16:27:18+00:00","og_image":[{"width":924,"height":616,"url":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2019\/12\/ravi-patel-VMGAbeeJTKo-unsplash-scaled.jpg","type":"image\/jpeg"}],"author":"Garrett Dunlap, B.S.","twitter_card":"summary_large_image","twitter_creator":"@nebulagenomics","twitter_site":"@nebulagenomics","twitter_misc":{"Verfasst von":"Garrett Dunlap, B.S.","Gesch\u00e4tzte Lesezeit":"1\u00a0Minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/#article","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/"},"author":{"name":"Garrett Dunlap, B.S.","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e"},"headline":"Beschleunigtes Altern (Gibson, 2019)","datePublished":"2021-01-06T05:30:53+00:00","dateModified":"2021-01-31T16:27:18+00:00","mainEntityOfPage":{"@id":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/"},"wordCount":187,"publisher":{"@id":"https:\/\/nebula.org\/blog\/de\/#organization"},"articleSection":["Berichte"],"inLanguage":"de"},{"@type":"WebPage","@id":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/","url":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/","name":"Die Genetik des beschleunigten Alterns (Gibson, 2019)","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/de\/#website"},"datePublished":"2021-01-06T05:30:53+00:00","dateModified":"2021-01-31T16:27:18+00:00","description":"Laden Sie Ihre DNA-Daten hoch, um genetische Varianten im Zusammenhang mit beschleunigtem Altern zu untersuchen (Gibson, 2019) und Ihren polygenen Score zu ermitteln.","breadcrumb":{"@id":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/#breadcrumb"},"inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nebula.org\/blog\/de\/genetik-des-beschleunigten-alterns-gibson-2019\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nebula.org\/blog\/de\/"},{"@type":"ListItem","position":2,"name":"Beschleunigtes Altern (Gibson, 2019)"}]},{"@type":"WebSite","@id":"https:\/\/nebula.org\/blog\/de\/#website","url":"https:\/\/nebula.org\/blog\/de\/","name":"Nebula Genomics Blog","description":"","publisher":{"@id":"https:\/\/nebula.org\/blog\/de\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nebula.org\/blog\/de\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/nebula.org\/blog\/de\/#organization","name":"Nebula Genomics","url":"https:\/\/nebula.org\/blog\/de\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Nebula Genomics"},"image":{"@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/facebook.com\/nebulagenomics","https:\/\/twitter.com\/nebulagenomics","https:\/\/www.instagram.com\/nebulagenomics\/","https:\/\/www.linkedin.com\/company\/nebula-genomics\/","https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics"]},{"@type":"Person","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e","name":"Garrett Dunlap, B.S.","image":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/nebula.org\/blog\/de\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","caption":"Garrett Dunlap, B.S."},"description":"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/de\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts\/10569","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/comments?post=10569"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts\/10569\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/media\/5506"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/media?parent=10569"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/categories?post=10569"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/tags?post=10569"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}