{"id":10707,"date":"2021-01-06T00:33:52","date_gmt":"2021-01-06T05:33:52","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-glaukom-makgregors-2018\/"},"modified":"2021-02-20T20:40:28","modified_gmt":"2021-02-21T01:40:28","slug":"genetik-des-glaukom-makgregors-2018","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-glaukom-makgregors-2018\/","title":{"rendered":"Glaukom (MacGregor, 2018)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Genomweite Assoziationsstudie zum Augeninnendruck deckt neue Wege zum Glaukom auf<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von \u00fcber 24 genetischen Varianten, die mit der Entwicklung eines Glaukoms korrelieren.<\/p>\n\n

BESCHREIBUNG:<\/strong> Das Glaukom ist eine der Hauptursachen f\u00fcr Blindheit bei \u00e4lteren Erwachsenen, obwohl es in jedem Alter auftreten kann. Es entsteht, wenn der Sehnerv, der das Auge mit dem Gehirn verbindet, besch\u00e4digt wird, h\u00e4ufig infolge eines erh\u00f6hten Drucks im Auge. Eine Methode, um das Fortschreiten des Glaukoms zu stoppen, besteht darin, diesen Druck zu verringern. Diese genomweite Assoziationsstudie mit \u00fcber 130.000 Teilnehmern europ\u00e4ischer Abstammung identifizierte 24 genetische Varianten, die mit einem erh\u00f6hten Augeninnendruck und dem Risiko f\u00fcr die Entwicklung dieser Erkrankung verbunden sind. Zwei der Varianten befinden sich in der N\u00e4he von Genen, die eine Rolle bei der Entwicklung und Funktion des Sehnervs spielen (CDKN2B und SIX6).<\/p>\n\n

HAST DU GEWUSST?<\/strong> W\u00e4hrend Sch\u00e4den durch diesen Zustand nicht r\u00fcckg\u00e4ngig gemacht werden k\u00f6nnen, kann die Fr\u00fcherkennung dazu beitragen, das Fortschreiten des Sehverlusts zu verlangsamen. Regelm\u00e4\u00dfige Augenuntersuchungen k\u00f6nnen einen erh\u00f6hten Augeninnendruck feststellen, bevor das Sehverm\u00f6gen beeintr\u00e4chtigt wird. [ QUELLE<\/a> ]]<\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> .<\/p>\n\n

\"Beispiel<\/a><\/figure>\n\n

GLAUCOMA-ASSOZIIERTE VARIANTEN:<\/strong> rs7518099, rs944801, rs2472493, rs2093210, rs9913911, rs28795989, rs945686, rs2745572, rs9284802, rs58073046, rs12699251, rs10505100, rs2024211, rs9853115, rs61394862, rs2935057, rs2073006, rs61861119, rs8141433, rs4141671, rs73174345, rs1013278, rs7924522, rs11710139<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong> Augeninnendruck<\/a><\/a>Was ist diese Krankheit?<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 24. Oktober 2019<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Genomweite Assoziationsstudie zum Augeninnendruck deckt neue Wege zum Glaukom auf ZUSAMMENFASSUNG: Identifizierung von \u00fcber 24 genetischen Varianten, die mit der Entwicklung eines Glaukoms korrelieren. BESCHREIBUNG: Das Glaukom ist eine der Hauptursachen f\u00fcr Blindheit bei \u00e4lteren Erwachsenen, obwohl es in …<\/p>\n

Glaukom (MacGregor, 2018)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5741,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10707","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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