{"id":10811,"date":"2021-01-06T00:35:43","date_gmt":"2021-01-06T05:35:43","guid":{"rendered":"https:\/\/nebula.org\/blog\/becken-organ-prolaps-olafsdottir-2020\/"},"modified":"2021-02-20T20:52:36","modified_gmt":"2021-02-21T01:52:36","slug":"becken-organ-prolaps-olafsdottir-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/becken-organ-prolaps-olafsdottir-2020\/","title":{"rendered":"Beckenorganprolaps (Olafsdottir, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Die genomweite Assoziation identifiziert sieben Loci f\u00fcr den Beckenorganprolaps in Island und der britischen Biobank<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 8 genetischen Varianten, die mit dem Beckenorganprolaps assoziiert sind.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Die Muskeln, die die Beckenorgane einer Frau unterst\u00fctzen, k\u00f6nnen geschw\u00e4cht werden, wodurch Organe wie die Blase und die Geb\u00e4rmutter tiefer in die Haut fallen Becken<\/em> . Dieser Zustand wird als Beckenorganprolaps bezeichnet, der zu Symptomen wie Druck im Beckenbereich, Darmproblemen und sexuellen Funktionsst\u00f6rungen f\u00fchrt. Es ist sehr h\u00e4ufig und betrifft fast jede dritte Frau irgendwann im Laufe ihres Lebens. Diese genomweite Assoziationsstudie untersuchte \u00fcber 355.000 Frauen europ\u00e4ischer Abstammung, um die genetischen Risikofaktoren f\u00fcr einen Beckenorganprolaps besser zu verstehen. Die Studie identifizierte 8 Varianten im Zusammenhang mit Beckenorganprolaps, die zusammen gesch\u00e4tzte 12% der Heritabilit\u00e4t der Erkrankung erkl\u00e4ren. Eine der entdeckten genetischen Varianten scheint das zu beeinflussen \u00d6strogen<\/em> Signalweg, w\u00e4hrend eine andere Variante die Aufrechterhaltung des Bindegewebes in der beeinflusst Becken<\/em> .<\/p>\n\n

HAST DU GEWUSST?<\/strong> Der Beckenorganprolaps wird am h\u00e4ufigsten durch Schwangerschaft und Geburt verursacht. Fettleibigkeit, Alter und Erkrankungen mit h\u00e4ufigem Husten sind ebenfalls Risikofaktoren f\u00fcr die Entwicklung der Erkrankung. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Probenergebnisse<\/a><\/figure>\n\n

ANALYSIERTE VARIANTEN:<\/strong> rs3820282 rs9306894 rs1430191 rs3791675 rs7682992 rs72624976 rs1247943 rs12325192<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Beckenvorfall<\/a>\u00d6strogen<\/a> <\/a>Video<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 31. M\u00e4rz 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Die genomweite Assoziation identifiziert sieben Loci f\u00fcr den Beckenorganprolaps in Island und der britischen Biobank ZUSAMMENFASSUNG: Identifizierung von 8 genetischen Varianten, die mit dem Beckenorganprolaps assoziiert sind. \u00dcBERBLICK: Die Muskeln, die die Beckenorgane einer Frau unterst\u00fctzen, k\u00f6nnen geschw\u00e4cht werden, …<\/p>\n

Beckenorganprolaps (Olafsdottir, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6021,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10811","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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