{"id":10857,"date":"2021-01-06T00:36:36","date_gmt":"2021-01-06T05:36:36","guid":{"rendered":"https:\/\/nebula.org\/blog\/maennlich-pubertaet-timing-hollis-2020\/"},"modified":"2021-02-20T20:57:42","modified_gmt":"2021-02-21T01:57:42","slug":"maennlich-pubertaet-timing-hollis-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/maennlich-pubertaet-timing-hollis-2020\/","title":{"rendered":"Zeitpunkt der m\u00e4nnlichen Pubert\u00e4t (Hollis, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Die Genomanalyse des Zeitpunkts der m\u00e4nnlichen Pubert\u00e4t zeigt die gemeinsame genetische Basis mit Haarfarbe und Lebensdauer<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 29 neuen Genomregionen, die mit dem Zeitpunkt der m\u00e4nnlichen Pubert\u00e4t assoziiert sind.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Der Zeitpunkt der Pubert\u00e4t, der Zeit der sexuellen Reifung f\u00fcr Jungen und M\u00e4dchen im Teenageralter, ist individuell sehr unterschiedlich. Es ist ein Merkmal, das durch eine Kombination von Umwelt- und genetischen Faktoren bestimmt wird. Diese Studie zielte darauf ab, die genetischen Grundlagen des Zeitpunkts der m\u00e4nnlichen Pubert\u00e4t spezifisch zu verstehen, wobei Voice Breaking als Proxy f\u00fcr die Pubert\u00e4t verwendet wurde. Zu diesem Zweck untersuchten die Forscher das Genom von \u00fcber 200.000 M\u00e4nnern europ\u00e4ischer Herkunft. Die Studie entdeckte 76 Genomregionen im Zusammenhang mit dem Zeitpunkt der m\u00e4nnlichen Pubert\u00e4t, von denen 29 neu sind. Diese genomischen Regionen sind mit Genen wie ALX4 und SRD5A2 verbunden, die an der Signalisierung eines Wachstumsfaktors und der Umwandlung von beteiligt sind Testosteron<\/em> in ein st\u00e4rkeres m\u00e4nnliches Hormon, Dihydrotestosteron. Dar\u00fcber hinaus identifizierte die Studie unerwartete genetische Zusammenh\u00e4nge zwischen dem Zeitpunkt der Pubert\u00e4t und der Haarfarbe. Beispielsweise hatten M\u00e4nner mit dunkleren Haarfarben im Vergleich zu M\u00e4nnern mit hellerer Haarfarbe eher einen fr\u00fcheren Zeitpunkt f\u00fcr die Pubert\u00e4t.<\/p>\n\n

HAST DU GEWUSST?<\/strong> W\u00e4hrend der Pubert\u00e4t nimmt der Kehlkopf oder die \u201eSprachbox\u201c eines Mannes tats\u00e4chlich an Gr\u00f6\u00dfe zu. Dadurch k\u00f6nnen die Stimmb\u00e4nder dicker werden, sodass die Stimme beim Vibrieren tiefer klingt. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

M\u00c4NNLICHE PUBERTY TIMING-ASSOZIIERTE VARIANTEN:<\/strong> rs4801593, rs4717905, rs11873906, rs12983109, rs61168554, rs10765711, rs11761054, rs4911442, rs17193410, rs6473008, rs60856990, rs2311380, rs583269, rs11671893, rs11603453, rs913588, rs12940636, rs12930815, rs1979835, rs11190751, rs10188334, rs6670873, rs780094, rs835648, rs2473234, rs6486116, rs7896371, rs1598656, rs438830, rs10934420, rs12895406, rs10164550, rs58611096, rs4900184, rs11836880, rs4664605, rs2049045, rs1514177, rs1121980, rs2842385, rs767657, rs10110581, rs7136086, rs7853970, rs6925777, rs7905367, rs12766208, rs2923177, rs3743266, rs138625771, rs6560353, rs9690350, rs6006984, rs6014657, rs35063026, rs112881196, rs12203592, rs34437050, rs62379978, rs10919759, rs17190166, rs17833789, rs7402990, rs77578010, rs3824915, rs10980922, rs2186245, rs73182377, rs2222746, rs71578952, rs1856502, rs6589961, rs9408817, rs142058842, rs1659127, rs11156429<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>\u00dcberblick \u00fcber die Pubert\u00e4t<\/a>Dihydrotestosteron<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 14. April 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Die Genomanalyse des Zeitpunkts der m\u00e4nnlichen Pubert\u00e4t zeigt die gemeinsame genetische Basis mit Haarfarbe und Lebensdauer ZUSAMMENFASSUNG: Identifizierung von 29 neuen Genomregionen, die mit dem Zeitpunkt der m\u00e4nnlichen Pubert\u00e4t assoziiert sind. \u00dcBERBLICK: Der Zeitpunkt der Pubert\u00e4t, der Zeit der …<\/p>\n

Zeitpunkt der m\u00e4nnlichen Pubert\u00e4t (Hollis, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6201,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10857","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie Genetik des Zeitpunkts der m\u00e4nnlichen Pubert\u00e4t - 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