{"id":10860,"date":"2021-01-06T00:36:40","date_gmt":"2021-01-06T05:36:40","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-von-fieber-anfaellen-feenstra-2014\/"},"modified":"2021-02-20T20:26:10","modified_gmt":"2021-02-21T01:26:10","slug":"genetik-von-fieber-anfaellen-feenstra-2014","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-von-fieber-anfaellen-feenstra-2014\/","title":{"rendered":"Fieberkr\u00e4mpfe (Feenstra, 2014)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> H\u00e4ufige Varianten im Zusammenhang mit allgemeinen und MMR-Impfstoff-bedingten Fieberkr\u00e4mpfen<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 6 genetischen Varianten im Zusammenhang mit fieberhaft<\/em> Anf\u00e4lle. <\/p>\n\n

\u00dcBERBLICK:<\/strong> Bei kleinen Kindern kann hohes Fieber Kr\u00e4mpfe ausl\u00f6sen, die zu unkontrollierbarem Zittern und Bewusstlosigkeit f\u00fchren. Dieser Zustand ist bekannt als fieberhaft<\/em> Anf\u00e4lle und ist eine schreckliche Erfahrung f\u00fcr viele Eltern. Sie sind jedoch in der Regel harmlos und auch recht h\u00e4ufig und betreffen 2 bis 9% (je nach ethnischer Zugeh\u00f6rigkeit) der Kinder vor dem 5. Lebensjahr. Da der Zustand durch Fieber verursacht wird, k\u00f6nnen sie nach Impfungen auftreten. Fieber ist eine relativ h\u00e4ufige Reaktion auf Impfungen mit dem Impfstoff gegen Masern, Mumps und R\u00f6teln (MMR). Weil wenig \u00fcber genetische Veranlagung zu bekannt ist fieberhaft<\/em> Anf\u00e4lle, insbesondere als Reaktion auf den MMR-Impfstoff, untersuchten in dieser Studie Genome von fast 9.000 Kindern europ\u00e4ischer Abstammung, um beitragende genetische Faktoren zu identifizieren. Die Studie entdeckte 2 genetische Varianten im Zusammenhang mit MMR fieberhaft<\/em> Anf\u00e4lle und 4 weitere Varianten im Zusammenhang mit der Erkrankung im Allgemeinen. Eine der identifizierten Varianten befindet sich in der N\u00e4he eines Gens, das eine Rolle bei der Immunantwort auf Virusinfektionen spielt. Eine andere Variante befindet sich in der N\u00e4he eines Gens, das f\u00fcr a kodiert Rezeptor<\/em> das wird vom Masernvirus verwendet, um in Zellen einzudringen. <\/p>\n\n

HAST DU GEWUSST?<\/strong> Die meisten Kinder mit fieberhaften Anf\u00e4llen ben\u00f6tigen keine Behandlung mit Medikamenten gegen Anf\u00e4lle. Der beste Weg, um auf fieberhafte Anf\u00e4lle zu reagieren, besteht darin, das Kind auf eine gesch\u00fctzte Oberfl\u00e4che zu legen und es sorgf\u00e4ltig zu beobachten. Es ist jedoch wichtig, den Grund f\u00fcr das Fieber zu verstehen und entsprechend zu behandeln. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Probenergebnisse<\/a><\/figure>\n\n

FEBRILE SEIZURE-ASSOZIIERTE VARIANTEN:<\/strong> rs114444506, rs6432860, rs273259, rs11105468, rs1318653, rs3769955<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Fact Sheet zu Fieberkr\u00e4mpfen<\/a>Fieberkr\u00e4mpfe (Video)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 21. April 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: H\u00e4ufige Varianten im Zusammenhang mit allgemeinen und MMR-Impfstoff-bedingten Fieberkr\u00e4mpfen ZUSAMMENFASSUNG: Identifizierung von 6 genetischen Varianten im Zusammenhang mit fieberhaft Anf\u00e4lle. \u00dcBERBLICK: Bei kleinen Kindern kann hohes Fieber Kr\u00e4mpfe ausl\u00f6sen, die zu unkontrollierbarem Zittern und Bewusstlosigkeit f\u00fchren. Dieser Zustand ist …<\/p>\n

Fieberkr\u00e4mpfe (Feenstra, 2014)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6226,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10860","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie Genetik fieberhafter Anf\u00e4lle (Feenstra, 2014)<\/title>\n<meta name=\"description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Fieberkr\u00e4mpfen (Feenstra, 2014) und ermitteln Sie Ihren polygenen Score.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-von-fieber-anfaellen-feenstra-2014\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Die Genetik fieberhafter Anf\u00e4lle (Feenstra, 2014)\" \/>\n<meta property=\"og:description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit Fieberkr\u00e4mpfen (Feenstra, 2014) und ermitteln Sie Ihren polygenen Score.\" \/>\n<meta property=\"og:url\" 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