{"id":10866,"date":"2021-01-06T00:36:46","date_gmt":"2021-01-06T05:36:46","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-der-membranoesen-nephropathie-xie-2020\/"},"modified":"2021-02-20T20:26:43","modified_gmt":"2021-02-21T01:26:43","slug":"genetik-der-membranoesen-nephropathie-xie-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-der-membranoesen-nephropathie-xie-2020\/","title":{"rendered":"Membran\u00f6se Nephropathie (Xie, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Die genetische Architektur der membran\u00f6sen Nephropathie und ihr Potenzial zur Verbesserung der nicht-invasiven Diagnose<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 4 Genomregionen, die mit membran\u00f6ser Nephropathie assoziiert sind, an Autoimmun<\/em> Erkrankung der Nieren. <\/p>\n\n

\u00dcBERBLICK:<\/strong> Nieren sind Organe, die Abfall und \u00fcbersch\u00fcssiges Wasser aus dem Blut entfernen, das schlie\u00dflich als Urin endet. Membran\u00f6se Nephropathie (MN) ist eine Autoimmun<\/em> Krankheit, die zu Nierenversagen f\u00fchrt. Diese genomweite Assoziationsstudie versuchte, genetische Varianten zu identifizieren, die mit einem erh\u00f6hten Risiko f\u00fcr membran\u00f6se Nephropathie verbunden sind. Durch die Untersuchung der genetischen Daten von \u00fcber 12.000 Personen ostasiatischer und europ\u00e4ischer Abstammung korrelierten 4 Regionen des Genoms mit einem erh\u00f6hten MN-Risiko. Alle identifizierten Varianten befinden sich in der N\u00e4he von Genen, die mit der Funktion des Immunsystems zusammenh\u00e4ngen, was unterstreicht, dass es sich um eine membran\u00f6se Nephropathie handelt Autoimmun<\/em> Krankheit. Dar\u00fcber hinaus wurden die Varianten zuvor mit einer anderen entz\u00fcndlichen Darmerkrankung in Verbindung gebracht Autoimmun<\/em> Bedingung. <\/p>\n\n

HAST DU GEWUSST?<\/strong> Behandlungen f\u00fcr membran\u00f6se Nephropathie umfassen Medikamente, die die Patienten dazu bringen, mehr zu urinieren, und eine salzarme Di\u00e4t. Es werden auch Medikamente eingesetzt, die das Immunsystem unter Kontrolle halten. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

MN-ASSOZIIERTE VARIANTEN:<\/strong> rs9271573, rs17831251, rs9405192, rs230540 <\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Ihre Nieren und wie sie funktionieren<\/a> Membran\u00f6se Neuropathie (Video)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 21. April 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Die genetische Architektur der membran\u00f6sen Nephropathie und ihr Potenzial zur Verbesserung der nicht-invasiven Diagnose ZUSAMMENFASSUNG: Identifizierung von 4 Genomregionen, die mit membran\u00f6ser Nephropathie assoziiert sind, an Autoimmun Erkrankung der Nieren. \u00dcBERBLICK: Nieren sind Organe, die Abfall und \u00fcbersch\u00fcssiges Wasser …<\/p>\n

Membran\u00f6se Nephropathie (Xie, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6231,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-10866","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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