{"id":9661,"date":"2021-01-05T23:56:28","date_gmt":"2021-01-06T04:56:28","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-anhedonie-station-2019\/"},"modified":"2021-02-20T20:56:15","modified_gmt":"2021-02-21T01:56:15","slug":"genetik-anhedonie-station-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-anhedonie-station-2019\/","title":{"rendered":"Anhedonia, eine Unf\u00e4higkeit, Vergn\u00fcgen zu empfinden (Ward, 2019)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Neuartige genomweite Assoziationen f\u00fcr Anhedonie, genetische Korrelation mit psychiatrischen St\u00f6rungen und polygene Assoziation mit der Gehirnstruktur<\/a> <\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 11 neuartigen Genomregionen im Zusammenhang mit Anhedonie, der Unf\u00e4higkeit, Vergn\u00fcgen zu empfinden.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Anhedonie bezieht sich auf einen Zustand, der durch die Unf\u00e4higkeit gekennzeichnet ist, sich an Aktivit\u00e4ten zu erfreuen, die als angenehm angesehen werden. Es ist ein h\u00e4ufiges Symptom f\u00fcr Depressionen und andere psychiatrische St\u00f6rungen und verringert die Lebensqualit\u00e4t. Die genetischen Grundlagen der Erkrankung sind nicht gut verstanden. Diese genomweite Studie mit \u00fcber 375.000 Personen europ\u00e4ischer Abstammung entdeckte 11 Genomregionen, die mit Anhedoniegef\u00fchlen assoziiert sind. Zusammen k\u00f6nnen diese Varianten \u00fcber 5% der Erblichkeit der Erkrankung erkl\u00e4ren. Die entdeckten Varianten schienen mit kleineren Volumina von Gehirnregionen zu assoziieren, die mit Belohnungs- und Vergn\u00fcgungsverarbeitung sowie anderen strukturellen Ver\u00e4nderungen im Gehirn verbunden sind.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Da die \u00fcblicherweise zur Behandlung von Depressionen verwendeten Medikamente h\u00e4ufig keine Lustgef\u00fchle f\u00f6rdern, untersuchen Forscher derzeit die Gespr\u00e4chstherapie zur Behandlung von Anhedonie. Die Gespr\u00e4chstherapie kann dazu beitragen, eine positive R\u00fcckkopplungsschleife im Gehirn in Gang zu setzen, die es den Patienten erm\u00f6glicht, wieder Freude zu empfinden. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

ASSOZIIERTE VARIANTEN:<\/strong> rs72923287, rs35416728, rs1965449, rs756739942, rs113740933<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong> Anhedonia<\/a>Anhedonia – Haus MD (Video)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 3. Januar 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Neuartige genomweite Assoziationen f\u00fcr Anhedonie, genetische Korrelation mit psychiatrischen St\u00f6rungen und polygene Assoziation mit der Gehirnstruktur ZUSAMMENFASSUNG: Identifizierung von 11 neuartigen Genomregionen im Zusammenhang mit Anhedonie, der Unf\u00e4higkeit, Vergn\u00fcgen zu empfinden. \u00dcBERBLICK: Anhedonie bezieht sich auf einen Zustand, der …<\/p>\n

Anhedonia, eine Unf\u00e4higkeit, Vergn\u00fcgen zu empfinden (Ward, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5146,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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