{"id":9702,"date":"2021-01-05T23:57:49","date_gmt":"2021-01-06T04:57:49","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-alkoholkonsums-evangelou-2019\/"},"modified":"2021-02-20T20:40:21","modified_gmt":"2021-02-21T01:40:21","slug":"genetik-des-alkoholkonsums-evangelou-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-alkoholkonsums-evangelou-2019\/","title":{"rendered":"Alkoholkonsum (Evangelou, 2019)"},"content":{"rendered":"\n<p><strong>STUDIENTITEL:<\/strong><a href=\"https:\/\/www.nature.com\/articles\/s41562-019-0653-z\"> Neue alkoholbezogene Gene deuten auf gemeinsame genetische Mechanismen bei neuropsychiatrischen Erkrankungen hin<\/a><\/p>\n\n<p><strong>ZUSAMMENFASSUNG:<\/strong> Entdeckung von 46 neuen Loci im Zusammenhang mit Alkoholkonsum und Verbindungen zu neuropsychiatrischen Erkrankungen wie Schizophrenie.<br\/><\/p>\n\n<p><strong>BESCHREIBUNG:<\/strong> \u00dcberm\u00e4\u00dfiger Alkoholkonsum ist eine der Hauptursachen f\u00fcr Tod und Behinderung weltweit mit einer Sterblichkeitsrate von bis zu 2,2% und 6,8% f\u00fcr Frauen bzw. M\u00e4nner. Es ist ein vererbbares komplexes Merkmal, aber bisher wurden nur wenige assoziierte genetische Varianten identifiziert. Diese genomweite Assoziation untersuchte 480.842 Personen europ\u00e4ischer Abstammung und entdeckte 46 neue genetische Varianten im Zusammenhang mit Alkoholkonsum. Die Studie sch\u00e4tzte auch, dass diese Varianten etwa 9% der Erblichkeit des Alkoholkonsums erkl\u00e4ren. Dar\u00fcber hinaus wurde gezeigt, dass mehrere Varianten die Aktivit\u00e4t von Genen im Gehirn beeinflussen, und es wurde bereits festgestellt, dass viele mit neuropsychiatrischen Erkrankungen wie Schizophrenie, Parkinson-Krankheit und Demenz assoziiert sind. Die Studie kommt zu dem Schluss, dass Alkoholkonsum und neuropsychiatrische St\u00f6rungen einen genetischen Mechanismus teilen.<br\/><\/p>\n\n<p><strong>HAST DU GEWUSST?<\/strong> M\u00f6glicherweise k\u00f6nnen Sie Ihren Alkoholkonsum senken, indem Sie ein striktes Trinklimit f\u00fcr sich selbst festlegen, keinen Alkohol an Ihrem Wohnort aufbewahren, besch\u00e4ftigt bleiben und um Unterst\u00fctzung bitten. [<a href=\"https:\/\/www.health.harvard.edu\/healthbeat\/11-ways-to-curb-your-drinking\"> QUELLE<\/a> ]]<\/p>\n\n<p><strong>BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die<a href=\"https:\/\/nebula.org\/blog\/de\/nebula-library-unlocking-gen-forschung\/\"> Nebula Research Library<\/a> .<\/p>\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/nebula.org\/free-dna-upload-analysis\/\"><img decoding=\"async\" width=\"1024\" height=\"375\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png\" alt=\"Beispiel f&#xFC;r personalisierte Ergebnisse am Nebel\" class=\"wp-image-5151\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png 1024w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-300x110.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-768x281.png 768w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1536x562.png 1536w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics.png 924w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n<p><\/p>\n\n<p><strong>ALKOHOLVERBRAUCHSVERBUNDENE VARIANTEN: <\/strong>rs145452708, rs11940694, rs1260326, rs1991556, rs9841829, rs1004787, rs13107325, rs838145, rs1104608, rs2071305, rs7121986, rs6969458, rs74424378, rs13024996, rs34060476, rs61873510, rs1421085, rs11648570, rs2277499, rs2310752, rs112635299, rs780569, rs10496076, rs71414193, rs16854020, rs485425, rs113443718, rs57281063, rs72768626, rs227179, rs9320010, rs2726034, rs13390019, rs7517344, rs4916723, rs10249167, rs7640, rs4794015, rs1053651, rs7698119, rs12312693, rs7958704, rs11114787, rs2356369, rs12031875, rs12646808, rs10078588, rs748919, rs785293, rs988748<\/p>\n\n<p><strong>ZUS\u00c4TZLICHE RESSOURCEN:<\/strong> <br\/><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/325135.php\">\u00dcberpr\u00fcfung des Alkoholkonsums auf dem Vormarsch<\/a><br\/><a href=\"https:\/\/www.alcoholrehabguide.org\/alcohol\/\">H\u00e4ufigste Gr\u00fcnde f\u00fcr Alkoholismus<\/a><\/p>\n\n<p><strong>W\u00d6CHENTLICHES UPDATE:<\/strong> 9. August 2019<\/p>\n\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\"><div class=\"wp-block-group__inner-container\"><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>STUDIENTITEL: Neue alkoholbezogene Gene deuten auf gemeinsame genetische Mechanismen bei neuropsychiatrischen Erkrankungen hin ZUSAMMENFASSUNG: Entdeckung von 46 neuen Loci im Zusammenhang mit Alkoholkonsum und Verbindungen zu neuropsychiatrischen Erkrankungen wie Schizophrenie. BESCHREIBUNG: \u00dcberm\u00e4\u00dfiger Alkoholkonsum ist eine der Hauptursachen f\u00fcr Tod und &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-des-alkoholkonsums-evangelou-2019\/\"> <span class=\"screen-reader-text\">Alkoholkonsum (Evangelou, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5211,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9702","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"<!-- 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