{"id":9749,"date":"2021-01-05T23:59:14","date_gmt":"2021-01-06T04:59:14","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-typ-2-diabetes-koch-2016\/"},"modified":"2021-02-20T20:53:23","modified_gmt":"2021-02-21T01:53:23","slug":"genetik-typ-2-diabetes-koch-2016","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-typ-2-diabetes-koch-2016\/","title":{"rendered":"Typ-2-Diabetes (Cook, 2016)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Eine multiethnische genomweite Assoziationsstudie identifiziert einen neuen Ort f\u00fcr die Anf\u00e4lligkeit f\u00fcr Typ-2-Diabetes<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung eines neuartigen genetischen Ortes, der mit dem Risiko der Entwicklung von Typ-2-Diabetes verbunden ist.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Glukose, auch als Blutzucker bekannt, kommt in vielen g\u00e4ngigen Lebensmitteln vor. Insulin, ein von der Bauchspeicheldr\u00fcse produziertes Hormon, hilft den K\u00f6rperzellen, Glukose aus dem Blut aufzunehmen und als Energiequelle zu nutzen. Typ-2-Diabetes (T2D) tritt auf, wenn die Bauchspeicheldr\u00fcse nicht gen\u00fcgend Insulin produziert oder die K\u00f6rperzellen nicht auf Insulin reagieren. Dies f\u00fchrt zu einem hohen Blutzuckerspiegel, der die Nerven, Blutgef\u00e4\u00dfe, Nieren und andere Organe sch\u00e4digen kann. W\u00e4hrend Umweltfaktoren, insbesondere die Ern\u00e4hrung, Risikofaktoren f\u00fcr T2D sind, kann auch eine Anf\u00e4lligkeit vererbt werden. Diese multiethnische genomweite Studie mit \u00fcber 71.000 Personen identifizierte einen neuartigen Ort, der mit dem Risiko der Entwicklung von T2D verbunden ist, und erh\u00f6hte die Gesamtzahl der bekannten Orte auf 10. Die neue Variante ist in der N\u00e4he der APOE<\/a> Gen, das hilft, Fette im Blut zu transportieren. APOE wurde zuvor mit mehreren anderen Erkrankungen in Verbindung gebracht, einschlie\u00dflich der Alzheimer-Krankheit.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Es wird gesch\u00e4tzt, dass 80% aller F\u00e4lle von Typ-2-Diabetes durch einen ges\u00fcnderen Lebensstil verhindert werden k\u00f6nnen. Dies kann durch eine Kombination von Ern\u00e4hrungsumstellungen (wie weniger ges\u00e4ttigten Fetten und mehr Ballaststoffen) und erh\u00f6hter k\u00f6rperlicher Aktivit\u00e4t erreicht werden. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

T2D-assoziierte Varianten:<\/strong> rs34872471, rs11927381, rs849134, rs13266634, rs7766070, rs10811661, rs9273401, rs3768321, rs157582, rs9687833<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Typ 2 Diabetes (Video)<\/a>APOE<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 19. Dezember 2019<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Eine multiethnische genomweite Assoziationsstudie identifiziert einen neuen Ort f\u00fcr die Anf\u00e4lligkeit f\u00fcr Typ-2-Diabetes ZUSAMMENFASSUNG: Identifizierung eines neuartigen genetischen Ortes, der mit dem Risiko der Entwicklung von Typ-2-Diabetes verbunden ist. \u00dcBERBLICK: Glukose, auch als Blutzucker bekannt, kommt in vielen g\u00e4ngigen …<\/p>\n

Typ-2-Diabetes (Cook, 2016)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5431,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9749","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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