{"id":9867,"date":"2021-01-06T00:02:15","date_gmt":"2021-01-06T05:02:15","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-der-colitis-ulcerosa-anderson-2011\/"},"modified":"2021-02-20T20:31:51","modified_gmt":"2021-02-21T01:31:51","slug":"genetik-der-colitis-ulcerosa-anderson-2011","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-der-colitis-ulcerosa-anderson-2011\/","title":{"rendered":"Colitis ulcerosa (Anderson, 2011)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Die Metaanalyse identifiziert 29 zus\u00e4tzliche Colitis ulcerosa-Risikostandorte, wodurch die Anzahl der best\u00e4tigten Assoziationen auf 47 erh\u00f6ht wird<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Genetische Varianten, die mit Entz\u00fcndungen und programmiertem Zelltod verbunden sind, k\u00f6nnen das Risiko f\u00fcr Colitis ulcerosa beeinflussen.<\/p>\n\n

BESCHREIBUNG:<\/strong> Colitis ulcerosa (UC) ist eine entz\u00fcndliche Darmerkrankung, die auftritt, wenn sich aufgrund einer anhaltenden Entz\u00fcndung Wunden im Dickdarm entwickeln. Symptome wie Durchfall, Bauchschmerzen und M\u00fcdigkeit entwickeln sich typischerweise im Laufe der Zeit. UC ist auch als vererbbar bekannt, die zugrunde liegenden genetischen Faktoren sind jedoch nicht gut verstanden. Diese Studie untersuchte \u00fcber 40.000 Personen europ\u00e4ischer Abstammung und entdeckte 29 neuartige genetische Varianten im Zusammenhang mit UC. Viele dieser Varianten waren zuvor mit dem programmierten Zelltod und dem Immunsystem, insbesondere Entz\u00fcndungen, verbunden. Es wird gesch\u00e4tzt, dass die neuen Varianten 16% der Heritabilit\u00e4t f\u00fcr UC erkl\u00e4ren, wobei alle signifikanten Varianten 28% der Heritabilit\u00e4t erkl\u00e4ren.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Um die Symptome einer Colitis ulcerosa zu reduzieren, trinken Sie viel Wasser, beschr\u00e4nken Sie Milchprodukte und trainieren Sie regelm\u00e4\u00dfig. [ QUELLE<\/a> ]]<\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> .<\/p>\n\n

\"Bericht<\/a><\/figure>\n\n

UC-ASSOZIIERTE VARIANTEN:<\/strong> rs9268853, rs6426833, rs11209026, rs10758669, rs2836878, rs6871626, rs6584283, rs6017342, rs1801274, rs10781499, rs16940202, rs9822268, rs3024505, rs6920220, rs17085007, rs7134599, rs4510766, rs2155219, rs798502, rs7608910, rs678170, rs7524102, rs7554511, rs1297265, rs2310173, Rs941823, Rs4246905, Rs267939, Rs2872507, Rs2838519, Rs4676406, Rs11676348, Rs907611, Rs2297441, Rs943072, Rs12261843, Rs254560, Rs6451493 *, Rs734999, Rs6451493 *<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong> Colitis ulcerosa – Symptome und Ursachen<\/a>Programmierter Zelltod (Video)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 30. August 2019<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Die Metaanalyse identifiziert 29 zus\u00e4tzliche Colitis ulcerosa-Risikostandorte, wodurch die Anzahl der best\u00e4tigten Assoziationen auf 47 erh\u00f6ht wird ZUSAMMENFASSUNG: Genetische Varianten, die mit Entz\u00fcndungen und programmiertem Zelltod verbunden sind, k\u00f6nnen das Risiko f\u00fcr Colitis ulcerosa beeinflussen. BESCHREIBUNG: Colitis ulcerosa (UC) …<\/p>\n

Colitis ulcerosa (Anderson, 2011)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5696,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9867","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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