{"id":9886,"date":"2021-01-06T00:02:34","date_gmt":"2021-01-06T05:02:34","guid":{"rendered":"https:\/\/nebula.org\/blog\/podokoniose-ayele-2012\/"},"modified":"2021-02-20T20:39:42","modified_gmt":"2021-02-21T01:39:42","slug":"podokoniose-ayele-2012","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/podokoniose-ayele-2012\/","title":{"rendered":"Podokoniose (Ayele, 2012)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> HLA Klasse II Ort und Anf\u00e4lligkeit f\u00fcr Podokoniose<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung einer Genomregion, die mit der Anf\u00e4lligkeit f\u00fcr die Entwicklung einer Podokoniose verbunden ist.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Podokoniose ist eine Krankheit, von der viele Menschen vielleicht noch nie geh\u00f6rt haben. In einigen Gemeinden auf der ganzen Welt ist jedoch fast 1 von 20 Personen betroffen. Die Krankheit betrifft haupts\u00e4chlich Landwirte und Menschen, die barfu\u00df auf rotem Lehmboden aus Vulkangestein laufen, das im tropischen Afrika, in Mittel- und S\u00fcdamerika sowie in Nordindien vorkommt. Wissenschaftler glauben, dass roter Lehmboden gro\u00dfe Mengen an Mineralien enth\u00e4lt, die \u00fcber die Haut der F\u00fc\u00dfe aufgenommen werden. Dies f\u00fchrt zu einer Reaktion des Immunsystems, die zu einer charakteristischen Schwellung der F\u00fc\u00dfe f\u00fchrt. Es wird angenommen, dass die Genetik \u00fcber 60% zum Risiko einer Person beitr\u00e4gt, eine Podokoniose zu entwickeln. Diese genomweite Studie untersuchte fast 400 Personen aus S\u00fcd\u00e4thiopien, um genetische Varianten im Zusammenhang mit Podokoniose zu identifizieren, und fand eine signifikante Assoziation mit der HLA-DQA1-Region, die eine wichtige Funktion im Immunsystem hat.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Die Weltgesundheitsorganisation glaubt, dass es m\u00f6glich ist, die Podokoniose auszurotten. Bem\u00fchungen zur Erh\u00f6hung der Verf\u00fcgbarkeit von Schuhen und zur Weiterentwicklung von Stra\u00dfen werden als Schl\u00fcsselstrategien zur Bek\u00e4mpfung der Krankheit angesehen. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

PODOCONIOSIS-ASSOZIIERTE VARIANTEN:<\/strong> rs17612858<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Weitere Informationen zu diesem Zustand<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 8. Februar 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: HLA Klasse II Ort und Anf\u00e4lligkeit f\u00fcr Podokoniose ZUSAMMENFASSUNG: Identifizierung einer Genomregion, die mit der Anf\u00e4lligkeit f\u00fcr die Entwicklung einer Podokoniose verbunden ist. \u00dcBERBLICK: Podokoniose ist eine Krankheit, von der viele Menschen vielleicht noch nie geh\u00f6rt haben. In einigen …<\/p>\n

Podokoniose (Ayele, 2012)<\/span> Read More 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