{"id":9897,"date":"2021-01-06T00:02:44","date_gmt":"2021-01-06T05:02:44","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-diffusen-lungen-b-zell-lymphoms-kleinstern-2019\/"},"modified":"2021-02-20T20:40:11","modified_gmt":"2021-02-21T01:40:11","slug":"genetik-des-diffusen-lungen-b-zell-lymphoms-kleinstern-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-diffusen-lungen-b-zell-lymphoms-kleinstern-2019\/","title":{"rendered":"Diffuses Lungen-B-Zell-Lymphom (Kleinstern, 2019)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Vererbte Varianten bei 3q13.33 und 3p24.1 sind mit dem Risiko eines diffusen gro\u00dfzelligen B-Zell-Lymphoms verbunden und implizieren Immunwege<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 2 neuen genetischen Varianten, die mit einem erh\u00f6hten Risiko f\u00fcr die Entwicklung eines diffusen gro\u00dfzelligen B-Zell-Lymphoms verbunden sind.<\/p>\n\n

BESCHREIBUNG:<\/strong> B-Zellen sind eine Art wei\u00dfer Blutk\u00f6rperchen, die eine wichtige Rolle in unserem Immunsystem spielen, indem sie Antik\u00f6rper produzieren, die helfen, Keime zu erkennen und zu zerst\u00f6ren. Ein abnormales B-Zell-Wachstum kann jedoch ein diffuses gro\u00dfzelliges B-Zell-Lymphom (DLBCL) bilden, eine aggressive Form von Krebs. Eine Familienanamnese von Lymphomen war zuvor mit einem erh\u00f6hten Risiko f\u00fcr die Entwicklung der Krankheit verbunden. Diese Studie untersuchte \u00fcber 17.000 Personen europ\u00e4ischer Abstammung, um genetische Faktoren, die mit einem erh\u00f6hten Risiko f\u00fcr die Entwicklung der Krankheit verbunden sind, weiter zu charakterisieren. Es wurden neue 2 Varianten identifiziert, die mit dem Risiko der Entwicklung von DLBCL verbunden sind. Beide befinden sich in der N\u00e4he von Genen, die eine Rolle im Immunsystem spielen.<\/p>\n\n

HAST DU GEWUSST?<\/strong> DLBCL reagiert au\u00dferordentlich empfindlich auf Chemotherapie, die im Allgemeinen als erste Behandlungslinie eingesetzt wird. Andere Behandlungsm\u00f6glichkeiten umfassen Strahlentherapie, Stammzelltransplantation und Immuntherapie. [ QUELLE<\/a> ]]<\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> .<\/p>\n\n

\"Beispiel<\/a><\/figure>\n\n

<\/p>\n\n

DLBCL-ASSOZIIERTE VARIANTEN:<\/strong> rs9831894, rs6773363<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong> B-Zellen<\/a>Was ist ein diffuses gro\u00dfzelliges B-Zell-Lymphom?<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 17. Oktober 2019<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Vererbte Varianten bei 3q13.33 und 3p24.1 sind mit dem Risiko eines diffusen gro\u00dfzelligen B-Zell-Lymphoms verbunden und implizieren Immunwege ZUSAMMENFASSUNG: Identifizierung von 2 neuen genetischen Varianten, die mit einem erh\u00f6hten Risiko f\u00fcr die Entwicklung eines diffusen gro\u00dfzelligen B-Zell-Lymphoms verbunden sind. …<\/p>\n

Diffuses Lungen-B-Zell-Lymphom (Kleinstern, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5736,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9897","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie 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