{"id":9936,"date":"2021-01-06T00:03:18","date_gmt":"2021-01-06T05:03:18","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-der-aplastischen-anaemie-savage-2020\/"},"modified":"2021-02-20T20:32:26","modified_gmt":"2021-02-21T01:32:26","slug":"genetik-der-aplastischen-anaemie-savage-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-der-aplastischen-anaemie-savage-2020\/","title":{"rendered":"Aplastische An\u00e4mie (Savage, 2020)"},"content":{"rendered":"\n

STUDIENTITEL:<\/strong> Genomweite Assoziationsstudie identifiziert HLA-DPB1 als signifikanten Risikofaktor f\u00fcr schwere aplastische An\u00e4mie<\/a><\/p>\n\n

ZUSAMMENFASSUNG:<\/strong> Identifizierung von 2 Genomregionen, die mit dem Risiko einer schweren aplastischen An\u00e4mie verbunden sind.<\/p>\n\n

\u00dcBERBLICK:<\/strong> Aplastische An\u00e4mie (AA) ist eine Autoimmunerkrankung, bei der das Knochenmark nicht gen\u00fcgend Blutzellen produziert. In schweren F\u00e4llen kann AA lebensbedrohlich werden. In dieser genomweiten Assoziationsstudie wurde versucht, Varianten zu identifizieren, die mit dem Risiko einer schweren aplastischen An\u00e4mie verbunden sind, indem genetische Informationen von fast 3.000 Personen europ\u00e4ischer Herkunft untersucht wurden. Die Ergebnisse zeigten 2 genetische Regionen, die mit dem Risiko einer schweren AA verbunden sind. Beide genetischen Regionen kodieren f\u00fcr Proteine des menschlichen Leukozyten-Antigen (HLA) -Systems, die eine Rolle bei der Regulation des Immunsystems spielen.<\/p>\n\n

HAST DU GEWUSST?<\/strong> Die Exposition gegen\u00fcber giftigen Chemikalien wie Pestiziden und Insektiziden kann das Risiko einer aplastischen An\u00e4mie erh\u00f6hen. Die Erkrankung kann auch eine vor\u00fcbergehende Nebenwirkung von Bestrahlung und Chemotherapie zur Behandlung von Krebs sein. [SOURCE]<\/a><\/p>\n\n

BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die Nebula Research Library<\/a> . <\/p>\n\n

\"Ergebnisse<\/a><\/figure>\n\n

<\/p>\n\n

ANALYSIERTE VARIANTEN:<\/strong> rs1042151, rs28367832<\/p>\n\n

ZUS\u00c4TZLICHE RESSOURCEN:<\/strong>Aplastische An\u00e4mie<\/a>Aplastische An\u00e4mie (Video)<\/a><\/p>\n\n

W\u00d6CHENTLICHES UPDATE:<\/strong> 15. Februar 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDIENTITEL: Genomweite Assoziationsstudie identifiziert HLA-DPB1 als signifikanten Risikofaktor f\u00fcr schwere aplastische An\u00e4mie ZUSAMMENFASSUNG: Identifizierung von 2 Genomregionen, die mit dem Risiko einer schweren aplastischen An\u00e4mie verbunden sind. \u00dcBERBLICK: Aplastische An\u00e4mie (AA) ist eine Autoimmunerkrankung, bei der das Knochenmark nicht gen\u00fcgend …<\/p>\n

Aplastische An\u00e4mie (Savage, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5796,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9936","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"\nDie Genetik der aplastischen An\u00e4mie (Savage, 2020)<\/title>\n<meta name=\"description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit aplastischer An\u00e4mie (Savage, 2020) und ermitteln Sie Ihren polygenen Score.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-der-aplastischen-anaemie-savage-2020\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Die Genetik der aplastischen An\u00e4mie (Savage, 2020)\" \/>\n<meta property=\"og:description\" content=\"Laden Sie Ihre DNA-Daten hoch, untersuchen Sie genetische Varianten im Zusammenhang mit aplastischer An\u00e4mie (Savage, 2020) und ermitteln Sie Ihren polygenen Score.\" \/>\n<meta property=\"og:url\" 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