{"id":9951,"date":"2021-01-06T00:03:26","date_gmt":"2021-01-06T05:03:26","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetik-des-wohlbefindens-baselmans-2019\/"},"modified":"2021-02-20T20:26:08","modified_gmt":"2021-02-21T01:26:08","slug":"genetik-des-wohlbefindens-baselmans-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/de\/genetik-des-wohlbefindens-baselmans-2019\/","title":{"rendered":"Wohlbefinden (Baselmans, 2019)"},"content":{"rendered":"\n<p><strong>STUDIENTITEL:<\/strong><a href=\"https:\/\/www.nature.com\/articles\/s41588-018-0320-8\"> Multivariate genomweite Analysen des Wohlf\u00fchlspektrums<\/a><\/p>\n\n<p><strong>ZUSAMMENFASSUNG:<\/strong> Neuartige Methode f\u00fcr multivariate Merkmale identifiziert 304 genetische Varianten, die mit dem Wohlbefinden verbunden sind.<\/p>\n\n<p><strong>\u00dcBERBLICK:<\/strong> Unser Wohlbefinden ist ein multivariates Merkmal, das typischerweise durch hohe Lebenszufriedenheit, positive Auswirkungen und Abwesenheit von Neurotizismus sowie depressive Symptome gekennzeichnet ist. Die Bestimmung genetischer Veranlagungen f\u00fcr unser Wohlbefinden kann schwierig sein, da eine komplexe Reihe genetischer Varianten dazu beitr\u00e4gt. Mit einer neuartigen Methode analysierte diese Studie das Genom von 160.000 Personen europ\u00e4ischer Abstammung, um 304 Varianten zu entdecken, die mit dem Wohlbefinden verbunden sind. Einige dieser identifizierten Varianten befinden sich in der N\u00e4he von Genen, die im Gehirngewebe stark exprimiert werden, insbesondere in der Hippocampusregion, die eine wichtige Rolle bei der Regulierung von Ged\u00e4chtnis, Lernen und Emotionen spielt. Diese neuartige Methode erh\u00f6hte auch die Anzahl der identifizierten genetischen Varianten, die mit dem Wohlbefinden verbunden sind, um 26%!<\/p>\n\n<p><strong>HAST DU GEWUSST?<\/strong> Studien haben gezeigt, dass Sport treiben, gut schlafen, Zeit mit geliebten Menschen verbringen, nach drau\u00dfen gehen, anderen helfen, das L\u00e4cheln \u00fcben und Ausfl\u00fcge planen Ihr allgemeines Gl\u00fcck steigern kann! <a href=\"https:\/\/www.inc.com\/jeff-haden\/10-scientifically-proven-ways-to-be-incredibly-happy-wed.html\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"  (opens in a new tab)\">[SOURCE]<\/a><\/p>\n\n<p><strong>BEISPIELERGEBNISSE:<\/strong> Erfahren Sie mehr \u00fcber die<a href=\"https:\/\/nebula.org\/blog\/de\/nebula-library-unlocking-gen-forschung\/\"> Nebula Research Library<\/a> .<\/p>\n\n<figure class=\"wp-block-image size-large\"><a href=\" https:\/\/nebula.org\/free-dna-upload-analysis\/\"><img decoding=\"async\" width=\"1024\" height=\"375\" src=\"http:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png\" alt=\"\" class=\"wp-image-1066\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png 1024w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-300x110.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-768x281.png 768w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1536x562.png 1536w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics.png 924w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n<p><strong>WELL-BEING-ASSOCIATED VARIANTS:<\/strong> rs4938021, rs483143, rs13213152, rs13212562, rs597462, rs8084280, rs11082011, rs7010590, rs2233980, rs13195401, rs2302832, rs433061, rs10491952, rs17702602, rs16903285, rs7832708, rs10774909, rs12967143, rs171697, rs11599236, rs716508, rs55748329, rs11214441, rs3734572, rs2179744, rs2921036, rs2149351, rs28427480, rs4543289, rs782207, rs3785234, rs7107356, rs2458167, rs4671459, rs1806153, rs115648484, rs2102341, rs3764512, rs4841662, rs61687445, rs11693031, rs1360692, rs11604333, rs12962538, rs10244364, rs3793577, rs3783007, rs2105841, rs7805419, rs2276825, rs11214596, rs13198298, rs619466, rs301806, rs10487459, rs1431071, rs261909, rs2093623, rs60045856, rs6601426, rs11610143, rs2678897, rs11644362, rs942866, rs1493914, rs6131010, rs10812851, rs6925748, rs35609938, rs6943746, rs9564496, rs7841297, rs215815, rs12552533, rs910187, rs2398144, rs2273653, rs210914, rs6776145, rs72808287, rs11633354, rs4955417, rs12125942, rs72694263, rs6705939, rs1371325, rs827123, rs272988 12817055, rs7243332, rs4654874, rs164640, rs6721577, rs7422667, rs2744228, rs4554778, rs703410, rs59211589, rs2051293, rs11068917, rs166418, rs247911, rs1187257, rs12794371, rs9957512, rs8001600, rs77648771, rs9380700, rs9298995, rs297346, rs7523829, rs12436091, rs1484680, rs4461738, rs10879715, rs10913160, rs61905363, rs651245, rs308805, rs7789405, rs4886920, rs2715147, rs17150537, rs9967747, rs4581549, rs17041417, rs12374076, rs815710, rs61867341, rs769688, rs4836189, rs17622606, rs1019706, rs3811935, rs6019826, rs60157091, rs34517207, rs204883, rs6773869, rs198457, rs3134012, rs17583539, rs1964390, rs7200826, rs111871194, rs7191427, rs2589341, rs9601120, rs13409834, rs10967509, rs66511648, rs9592461, rs10746509, rs78324365, rs10936879, rs11876796, rs115091345, rs9332801, rs4914930, rs35722835, rs4652676, rs7396827, rs4712936, rs11605020, rs1147478, rs7021901, rs10838629, rs1329572, rs12910872, rs41316748, rs1563245, rs17049478, rs977747, rs17186681, rs7819525, rs285004, rs7819525, rs285004 rs7154329, rs1510386, rs10485622, rs9546806, rs17570807, rs74504435, rs4409766, rs16958292, rs779995, rs72932350, rs10168771, rs1191600, rs1919159, rs12458596, rs1983949, rs1551840, rs12513440, rs77414181, rs13262595, rs1950835, rs73190080, rs71384258, rs34945223, rs4968736, rs117599630, rs310763, rs3846828, rs6433563, rs6771469, rs28680958, rs35258156, rs4271063, rs306755, rs10061069, rs79367487, rs5754712, rs6535577, rs655836, rs4757136, rs77129413, rs12517438, rs9883788, rs7633673, rs314262, rs2876520, rs1892350, rs2042395, rs2469903, rs4739938, rs6931902, rs1016306, rs12910903, rs1072880<\/p>\n\n<p><strong>ZUS\u00c4TZLICHE RESSOURCEN:<\/strong><br\/><a href=\"https:\/\/www.psychologytoday.com\/us\/blog\/media-spotlight\/201302\/can-happiness-be-genetic\">Wohlf\u00fchlspektrum<\/a><br\/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Hippocampus\">Hippocampus<\/a><\/p>\n\n<p><strong>W\u00d6CHENTLICHES UPDATE:<\/strong> 2. November 2019<br\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>STUDIENTITEL: Multivariate genomweite Analysen des Wohlf\u00fchlspektrums ZUSAMMENFASSUNG: Neuartige Methode f\u00fcr multivariate Merkmale identifiziert 304 genetische Varianten, die mit dem Wohlbefinden verbunden sind. \u00dcBERBLICK: Unser Wohlbefinden ist ein multivariates Merkmal, das typischerweise durch hohe Lebenszufriedenheit, positive Auswirkungen und Abwesenheit von Neurotizismus &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/de\/genetik-des-wohlbefindens-baselmans-2019\/\"> <span class=\"screen-reader-text\">Wohlbefinden (Baselmans, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5766,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4980],"tags":[],"class_list":["post-9951","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berichte"],"yoast_head":"<!-- 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He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/de\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts\/9951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/comments?post=9951"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/posts\/9951\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/media\/5766"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/media?parent=9951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/categories?post=9951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/de\/wp-json\/wp\/v2\/tags?post=9951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}