{"id":10038,"date":"2021-01-06T00:05:57","date_gmt":"2021-01-06T05:05:57","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-lvedv-pirruccello-2020\/"},"modified":"2021-02-20T20:26:10","modified_gmt":"2021-02-21T01:26:10","slug":"genetica-de-lvedv-pirruccello-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-de-lvedv-pirruccello-2020\/","title":{"rendered":"Volumen telediast\u00f3lico del ventr\u00edculo izquierdo (Pirruccello, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> El an\u00e1lisis de im\u00e1genes de resonancia magn\u00e9tica card\u00edaca en 36.000 personas arroja conocimientos gen\u00e9ticos sobre la miocardiopat\u00eda dilatada<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de 14 variantes gen\u00e9ticas asociadas al volumen telediast\u00f3lico del ventr\u00edculo izquierdo (LVEDV).<\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> El coraz\u00f3n humano es un m\u00fasculo que bombea sangre por todo el cuerpo. Consta de 4 c\u00e1maras: 2 aur\u00edculas (izquierda y derecha) y 2 ventr\u00edculos (izquierda y derecha). La sangre que se ha enriquecido con ox\u00edgeno en los pulmones ingresa a la aur\u00edcula izquierda y luego fluye hacia el ventr\u00edculo izquierdo desde donde se bombea a todas las dem\u00e1s partes del cuerpo. El volumen telediast\u00f3lico del ventr\u00edculo izquierdo (LVEDV) es el volumen de sangre en un ventr\u00edculo izquierdo relajado justo antes de que se contraiga y bombee sangre al cuerpo. El LVEDV promedio es de 120 ml para las mujeres y 150 ml para los hombres y se puede usar como una medida de la salud del coraz\u00f3n. Este estudio de asociaci\u00f3n de todo el genoma examin\u00f3 los genomas de 36.000 individuos de ascendencia europea para comprender mejor la base gen\u00e9tica del LVEDV. El estudio identific\u00f3 14 regiones gen\u00f3micas asociadas con LVEDV ajustadas por \u00e1rea de superficie corporal. El estudio tambi\u00e9n encontr\u00f3 una fuerte relaci\u00f3n inversa entre la puntuaci\u00f3n polig\u00e9nica para LVEDV m\u00e1s grande y el hipotiroidismo. <\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> En promedio, el coraz\u00f3n humano bombea ~ 2,000 galones (7,600 litros) de sangre por todo el cuerpo todos los d\u00edas. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

VARIANTES ASOCIADAS A LVEDV:<\/strong> rs1873164, rs9797817, rs72967533, rs72840788, rs73028849, rs1976402, rs6458349, rs9480737, rs7502466, rs12499670, rs10850034<\/p>\n\n

RECURSOS ADICIONALES:<\/strong>El coraz\u00f3n (Video)<\/a>Como funciona el corazon<\/a>Volumen telediast\u00f3lico<\/a><\/p>\n\n

USTED TAMBI\u00c9N PODR\u00cdA ESTAR INTERESADO EN:<\/strong> Fracci\u00f3n de eyecci\u00f3n del ventr\u00edculo izquierdo (Pirruccello, 2020)<\/a>Volumen telesist\u00f3lico del ventr\u00edculo izquierdo (Pirruccello, 2020)<\/a>Volumen sist\u00f3lico (Pirruccello, 2020)<\/a>Miocardiopat\u00eda (Meder, 2014)<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 19 de mayo de 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: El an\u00e1lisis de im\u00e1genes de resonancia magn\u00e9tica card\u00edaca en 36.000 personas arroja conocimientos gen\u00e9ticos sobre la miocardiopat\u00eda dilatada RESUMEN: Identificaci\u00f3n de 14 variantes gen\u00e9ticas asociadas al volumen telediast\u00f3lico del ventr\u00edculo izquierdo (LVEDV). VISI\u00d3N GENERAL: El coraz\u00f3n humano …<\/p>\n

Volumen telediast\u00f3lico del ventr\u00edculo izquierdo (Pirruccello, 2020)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6374,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10038","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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