{"id":10096,"date":"2021-01-06T00:07:19","date_gmt":"2021-01-06T05:07:19","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-longevidad-timmers-2020\/"},"modified":"2021-02-20T20:26:20","modified_gmt":"2021-02-21T01:26:20","slug":"genetica-de-longevidad-timmers-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-de-longevidad-timmers-2020\/","title":{"rendered":"Longevidad (Timmers, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> La exploraci\u00f3n gen\u00f3mica multivariada implica nuevos loci y metabolismo del hemo en el envejecimiento humano<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de 10 variantes gen\u00e9ticas asociadas a la longevidad.<\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> La longevidad es un rasgo que se define como tener una vida \u00fatil m\u00e1s larga que la mayor\u00eda de las personas. Este estudio defini\u00f3 espec\u00edficamente la longevidad como vivir m\u00e1s que el 90% de las personas. Aunque factores como la dieta y el acceso a la atenci\u00f3n m\u00e9dica influyen en la duraci\u00f3n de la vida de una persona, la gen\u00e9tica tambi\u00e9n influye en la longevidad. Este estudio de asociaci\u00f3n de todo el genoma examin\u00f3 a m\u00e1s de 36.000 individuos de ascendencia europea para determinar los factores gen\u00e9ticos asociados con la longevidad. El estudio encontr\u00f3 10 variantes gen\u00e9ticas que est\u00e1n relacionadas con el rasgo, pero tambi\u00e9n la esperanza de vida y la salud de los padres. La variante con la asociaci\u00f3n m\u00e1s fuerte (rs429358) est\u00e1 en el gen APOE y est\u00e1 relacionada con la enfermedad de Alzheimer. Esta variante por s\u00ed sola imparte ~ 1,7 m\u00e1s probabilidades de vivir m\u00e1s que el 90% de las personas.<\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> Las \u00abzonas azules\u00bb son lugares alrededor del mundo donde las personas tienden a vivir mucho m\u00e1s tiempo que el promedio. Okinawa (Jap\u00f3n) e Ikaria (Grecia) son dos de estos lugares, donde un alto porcentaje de habitantes vive hasta los 90 a\u00f1os. Las dietas ricas en plantas y las fuertes conexiones familiares son rasgos comunes en muchas \u00abzonas azules\u00bb. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

VARIANTES ASOCIADAS A LA LONGEVIDAD:<\/strong> rs429358, rs10455872, rs7859727, rs61905747, rs6511720, rs12830425, rs1159806, rs4783780, rs2643826, rs17499404<\/p>\n\n

RECURSOS ADICIONALES:<\/strong><\/a>La ciencia del envejecimiento (Video)<\/a>\u00bfLa longevidad est\u00e1 determinada por la gen\u00e9tica?<\/a><\/p>\n\n

USTED TAMBI\u00c9N PODR\u00cdA ESTAR INTERESADO EN:<\/strong> Longevidad (Deelen, 2019)<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 28 de julio de 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: La exploraci\u00f3n gen\u00f3mica multivariada implica nuevos loci y metabolismo del hemo en el envejecimiento humano RESUMEN: Identificaci\u00f3n de 10 variantes gen\u00e9ticas asociadas a la longevidad. VISI\u00d3N GENERAL: La longevidad es un rasgo que se define como tener …<\/p>\n

Longevidad (Timmers, 2020)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6669,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10096","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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