{"id":10138,"date":"2021-01-06T00:08:13","date_gmt":"2021-01-06T05:08:13","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-adenocarcinoma-de-pulmon-mckay-2017\/"},"modified":"2021-02-20T20:28:46","modified_gmt":"2021-02-21T01:28:46","slug":"genetica-adenocarcinoma-de-pulmon-mckay-2017","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-adenocarcinoma-de-pulmon-mckay-2017\/","title":{"rendered":"Adenocarcinoma de pulm\u00f3n (McKay, 2017)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> El an\u00e1lisis de asociaci\u00f3n a gran escala identifica nuevos loci de susceptibilidad al c\u00e1ncer de pulm\u00f3n y heterogeneidad en la susceptibilidad gen\u00e9tica a trav\u00e9s de subtipos histol\u00f3gicos<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de 6 nuevas regiones gen\u00f3micas asociadas con el adenocarcinoma de pulm\u00f3n. <\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> El c\u00e1ncer de pulm\u00f3n es una afecci\u00f3n en la que las c\u00e9lulas de los pulmones se dividen sin control. El adenocarcinoma de pulm\u00f3n es un subtipo que representa aproximadamente el 40% de todos los c\u00e1nceres de pulm\u00f3n. Es causada por mutaciones en las c\u00e9lulas glandulares de los pulmones productoras de moco. En promedio, el adenocarcinoma de pulm\u00f3n tiende a crecer m\u00e1s lentamente que otros subtipos de c\u00e1ncer de pulm\u00f3n. Para comprender mejor la base gen\u00e9tica de este c\u00e1ncer, este estudio examin\u00f3 los genomas de aproximadamente 67.000 individuos. Los investigadores identificaron 6 nuevas regiones asociadas con el adenocarcinoma de pulm\u00f3n. La mitad de estas regiones se encuentran cerca de genes relacionados con la longitud de los tel\u00f3meros, que se acorta con la edad. En general, las variantes gen\u00e9ticas identificadas ayudan a explicar el 6,7% de la heredabilidad de este c\u00e1ncer. <\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> El tipo m\u00e1s com\u00fan de c\u00e1ncer de pulm\u00f3n en mujeres es el adenocarcinoma. Adem\u00e1s, el adenocarcinoma est\u00e1 menos asociado con el tabaquismo. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

VARIANTES ASOCIADAS A ADENOCARCINOMA PULMONAR:<\/strong> rs7705526, rs77468143, rs13080835, rs115917190, rs4236709, rs1056562, rs885518, rs41309931<\/p>\n\n

RECURSOS ADICIONALES:<\/strong>C\u00e1ncer de pulm\u00f3n (video)<\/a>Tipos de c\u00e1ncer de pulm\u00f3n<\/a>Viviendo con c\u00e1ncer de pulm\u00f3n<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 12 de mayo de 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: El an\u00e1lisis de asociaci\u00f3n a gran escala identifica nuevos loci de susceptibilidad al c\u00e1ncer de pulm\u00f3n y heterogeneidad en la susceptibilidad gen\u00e9tica a trav\u00e9s de subtipos histol\u00f3gicos RESUMEN: Identificaci\u00f3n de 6 nuevas regiones gen\u00f3micas asociadas con el …<\/p>\n

Adenocarcinoma de pulm\u00f3n (McKay, 2017)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6344,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10138","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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