{"id":10164,"date":"2021-01-06T00:08:32","date_gmt":"2021-01-06T05:08:32","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-lvesv-pirruccello-2020\/"},"modified":"2021-02-20T20:20:05","modified_gmt":"2021-02-21T01:20:05","slug":"genetica-de-lvesv-pirruccello-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-de-lvesv-pirruccello-2020\/","title":{"rendered":"Volumen telesist\u00f3lico del ventr\u00edculo izquierdo (Pirruccello, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> El an\u00e1lisis de im\u00e1genes de resonancia magn\u00e9tica card\u00edaca en 36.000 personas arroja conocimientos gen\u00e9ticos sobre la miocardiopat\u00eda dilatada<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de 28 variantes gen\u00e9ticas asociadas al volumen telesist\u00f3lico del ventr\u00edculo izquierdo (LVESV).<\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> El coraz\u00f3n humano es un m\u00fasculo que bombea sangre por todo el cuerpo. Consta de 4 c\u00e1maras: 2 aur\u00edculas (izquierda y derecha) y 2 ventr\u00edculos (izquierda y derecha). La sangre que se ha enriquecido con ox\u00edgeno en los pulmones ingresa a la aur\u00edcula izquierda y luego fluye hacia el ventr\u00edculo izquierdo desde donde se bombea a todas las dem\u00e1s partes del cuerpo. El volumen telesist\u00f3lico del ventr\u00edculo izquierdo (LVESV) es el volumen de sangre que permanece en el ventr\u00edculo izquierdo al final de una bomba. El LVESV promedio es de 41 ml para las mujeres y 58 ml para los hombres y se puede usar como una medida de la salud del coraz\u00f3n. Este estudio de asociaci\u00f3n de todo el genoma examin\u00f3 los genomas de 36.000 individuos de ascendencia europea para comprender mejor la base gen\u00e9tica del LVESV. El estudio identific\u00f3 28 regiones gen\u00f3micas asociadas con LVESV ajustadas por \u00e1rea de superficie corporal. El estudio tambi\u00e9n encontr\u00f3 que una puntuaci\u00f3n polig\u00e9nica alta para LVESV ajustado al \u00e1rea de la superficie corporal estaba fuertemente correlacionada con el riesgo de miocardiopat\u00eda dilatada. Esta condici\u00f3n describe un m\u00fasculo card\u00edaco que est\u00e1 demasiado estirado y delgado y no puede bombear de manera eficiente.<\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> La expresi\u00f3n \u00abla risa es la mejor medicina\u00bb tiene algo de verdad. La risa puede ser beneficiosa para la salud de su coraz\u00f3n, ya que permite que las arterias se relajen y se vuelvan m\u00e1s flexibles, lo que facilita el flujo sangu\u00edneo. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

VARIANTES ASOCIADAS A LVESV:<\/strong> rs72840788, rs945425, rs2562845, rs73028849, rs5760061, rs3176326, rs10421891, rs12452367, rs34373805, rs8063213, rs79502300, rs1962104, rs11023059, rs189569984, rs9892651, rs1499813, rs2302455, rs11748963, rs10871753, rs116904997, rs190093681, rs709208, rs2886037, rs242562<\/p>\n\n

RECURSOS ADICIONALES:<\/strong>El coraz\u00f3n (Video)<\/a>Como funciona el corazon<\/a><\/p>\n\n

USTED TAMBI\u00c9N PODR\u00cdA ESTAR INTERESADO EN:<\/strong> Fracci\u00f3n de eyecci\u00f3n del ventr\u00edculo izquierdo (Pirruccello, 2020)<\/a> Volumen telediast\u00f3lico del ventr\u00edculo izquierdo (Pirruccello, 2020)<\/a>Volumen sist\u00f3lico (Pirruccello, 2020)<\/a>Insuficiencia card\u00edaca (Shah, 2020)<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 19 de mayo de 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: El an\u00e1lisis de im\u00e1genes de resonancia magn\u00e9tica card\u00edaca en 36.000 personas arroja conocimientos gen\u00e9ticos sobre la miocardiopat\u00eda dilatada RESUMEN: Identificaci\u00f3n de 28 variantes gen\u00e9ticas asociadas al volumen telesist\u00f3lico del ventr\u00edculo izquierdo (LVESV). VISI\u00d3N GENERAL: El coraz\u00f3n humano …<\/p>\n

Volumen telesist\u00f3lico del ventr\u00edculo izquierdo (Pirruccello, 2020)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6379,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10164","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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