{"id":10240,"date":"2021-01-06T00:11:52","date_gmt":"2021-01-06T05:11:52","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-delgadez-orthofer-2020\/"},"modified":"2021-02-20T20:19:21","modified_gmt":"2021-02-21T01:19:21","slug":"genetica-delgadez-orthofer-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-delgadez-orthofer-2020\/","title":{"rendered":"Delgadez (Orthofer, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> Identificaci\u00f3n de ALK en delgadez<\/a><\/p>\n\n

RESUMEN:<\/strong> Descubrimiento de 5 variantes gen\u00e9ticas asociadas a la delgadez.<\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> Aunque la dieta y el ejercicio son importantes para mantener un peso corporal saludable, las personas que comen alimentos similares y hacen ejercicio en cantidades similares pueden diferir en su peso. La mayor\u00eda de los estudios que buscan variantes gen\u00e9ticas asociadas con el \u00edndice de masa corporal (IMC) comparan a individuos obesos con controles sanos. En cambio, este estudio busc\u00f3 asociaciones con la delgadez. Los investigadores compararon el 1,9% m\u00e1s delgado de las personas (sexto percentil de IMC; 881 individuos) en el biobanco de Estonia con personas que ten\u00edan un peso corporal promedio (percentil 30-50 de IMC; 3,173 individuos) y encontraron 5 variantes asociadas con la delgadez. Una de las variantes (rs568057364) est\u00e1 dentro del gen ALK que se sabe que juega un papel en el c\u00e1ncer. Los investigadores alteraron el gen ALK en ratones y encontraron que resultaba en resistencia a la obesidad inducida por la dieta.<\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> Las personas con bajo peso a menudo tienen deficiencias nutricionales porque no consumen suficientes alimentos para recibir todas las vitaminas y minerales que su cuerpo necesita. Es importante obtener suficientes micronutrientes, incluso cuando se limita la ingesta de calor\u00edas. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

VARIANTES ASOCIADAS A LA DELGURA:<\/strong> rs6574213, rs79938778, rs61685635, rs568057364, rs4521442<\/p>\n\n

RECURSOS ADICIONALES:<\/strong>P\u00e9rdida de peso e \u00edndice de masa corporal (video)<\/a>Calculadora de IMC<\/a><\/p>\n\n

USTED TAMBI\u00c9N PODR\u00cdA ESTAR INTERESADO EN:<\/strong> Peso al nacer y susceptibilidad a enfermedades (Horikoshi, 2017)<\/a>\u00cdndice de masa corporal (Couto Alves, 2019)<\/a>\u00cdndice de masa corporal (Anderson, 2020)<\/a>Obesidad (Jiao, 2011)<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 16 de junio de 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: Identificaci\u00f3n de ALK en delgadez RESUMEN: Descubrimiento de 5 variantes gen\u00e9ticas asociadas a la delgadez. VISI\u00d3N GENERAL: Aunque la dieta y el ejercicio son importantes para mantener un peso corporal saludable, las personas que comen alimentos similares …<\/p>\n

Delgadez (Orthofer, 2020)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6509,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10240","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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