{"id":10787,"date":"2021-01-06T00:35:17","date_gmt":"2021-01-06T05:35:17","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-sars-coronavirus-infeccion-ching-2010\/"},"modified":"2021-02-20T20:36:01","modified_gmt":"2021-02-21T01:36:01","slug":"genetica-de-sars-coronavirus-infeccion-ching-2010","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-de-sars-coronavirus-infeccion-ching-2010\/","title":{"rendered":"Infecci\u00f3n por coronavirus del SARS (Ching, 2010)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> Importancia del gen de resistencia a mixovirus A (MxA) – 123C> Un polimorfismo de nucle\u00f3tido \u00fanico en la inducci\u00f3n de interfer\u00f3n \u03b2 suprimido del s\u00edndrome respiratorio agudo severo Infecci\u00f3n por coronavirus<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de una variante gen\u00e9tica asociada con un menor riesgo de SARS coronavirus<\/em> infecci\u00f3n.<\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> El s\u00edndrome respiratorio agudo severo (SARS) coronavirus<\/em> surgi\u00f3 en 2003 en China. En poco m\u00e1s de un a\u00f1o, infect\u00f3 a 8000 personas y provoc\u00f3 m\u00e1s de 900 muertes en todo el mundo. Los s\u00edntomas t\u00edpicos incluyen fiebre alta, dolor de cabeza y tos seca. Estudios anteriores han demostrado que interferones<\/em> puede inhibir la replicaci\u00f3n del SARS coronavirus<\/em> al inducir la producci\u00f3n de prote\u00ednas antivirales como MxA. Este estudio demostr\u00f3 que una variante gen\u00e9tica (rs17000900) cercana al gen MxA influye en su actividad cuando las c\u00e9lulas est\u00e1n expuestas a interferones<\/em> . El estudio tambi\u00e9n examin\u00f3 la informaci\u00f3n gen\u00e9tica de m\u00e1s de 1200 individuos de ascendencia china y estableci\u00f3 una relaci\u00f3n entre esta variante gen\u00e9tica y el riesgo de SARS. coronavirus<\/em> infecci\u00f3n. Los resultados sugieren que el alelo A de la variante rs17000900 est\u00e1 relacionado con una menor susceptibilidad al SARS. coronavirus<\/em> infecci\u00f3n. (Nota: este estudio no es un estudio de asociaci\u00f3n de todo el genoma. Solo se genotiparon selectivamente algunas variantes).<\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> Los coronavirus tambi\u00e9n son responsables de la pandemia de MERS (s\u00edndrome respiratorio de Oriente Medio) a principios de la d\u00e9cada de 2010. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"Resultados<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ANALIZADAS DEL CORONAVIRUS DEL SARS:<\/strong> rs17000900<\/p>\n\n

RECURSOS ADICIONALES:<\/strong>S\u00edndrome respiratorio agudo severo (SARS)<\/a>Lecci\u00f3n aprendida del brote de SARS (video)<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 23 de marzo de 2020<\/p>\n\n

Para obtener actualizaciones sobre la gen\u00e9tica de COVID-19, visite: https:\/\/nebula.org\/blog\/category\/science\/<\/a><\/p>\n\n

Puedes aprender m\u00e1s sobre pruebas de coronavirus en el hogar<\/a> en nuestra rese\u00f1a!<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: Importancia del gen de resistencia a mixovirus A (MxA) – 123C> Un polimorfismo de nucle\u00f3tido \u00fanico en la inducci\u00f3n de interfer\u00f3n \u03b2 suprimido del s\u00edndrome respiratorio agudo severo Infecci\u00f3n por coronavirus RESUMEN: Identificaci\u00f3n de una variante gen\u00e9tica …<\/p>\n

Infecci\u00f3n por coronavirus del SARS (Ching, 2010)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5939,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10787","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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