{"id":10814,"date":"2021-01-06T00:35:46","date_gmt":"2021-01-06T05:35:46","guid":{"rendered":"https:\/\/nebula.org\/blog\/prolapso-de-organos-pelvicos-olafsdottir-2020\/"},"modified":"2021-02-20T20:48:48","modified_gmt":"2021-02-21T01:48:48","slug":"prolapso-de-organos-pelvicos-olafsdottir-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/prolapso-de-organos-pelvicos-olafsdottir-2020\/","title":{"rendered":"Prolapso de \u00f3rganos p\u00e9lvicos (Olafsdottir, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> La asociaci\u00f3n de todo el genoma identifica siete loci para el prolapso de \u00f3rganos p\u00e9lvicos en Islandia y el Biobanco del Reino Unido<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de 8 variantes gen\u00e9ticas asociadas al prolapso de \u00f3rganos p\u00e9lvicos.<\/p>\n\n

VISI\u00d3N GENERAL:<\/strong> Los m\u00fasculos que sostienen los \u00f3rganos p\u00e9lvicos de una mujer pueden debilitarse, haciendo que \u00f3rganos como la vejiga y el \u00fatero caigan m\u00e1s abajo en el pelvis<\/em> . Esta afecci\u00f3n se llama prolapso de \u00f3rganos p\u00e9lvicos y produce s\u00edntomas como presi\u00f3n en el \u00e1rea p\u00e9lvica, problemas intestinales y disfunci\u00f3n sexual. Es muy com\u00fan y afecta a casi 1 de cada 3 mujeres en alg\u00fan momento de su vida. Este estudio de asociaci\u00f3n de todo el genoma examin\u00f3 a m\u00e1s de 355.000 mujeres de ascendencia europea para comprender mejor los factores de riesgo gen\u00e9ticos del prolapso de \u00f3rganos p\u00e9lvicos. El estudio identific\u00f3 8 variantes asociadas con el prolapso de \u00f3rganos p\u00e9lvicos, que en conjunto explican aproximadamente el 12% de la heredabilidad de la afecci\u00f3n. Una de las variantes gen\u00e9ticas descubiertas parece afectar la estr\u00f3geno<\/em> v\u00eda de se\u00f1alizaci\u00f3n, mientras que otra variante influye en el mantenimiento del tejido conectivo en el pelvis<\/em> .<\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> El prolapso de \u00f3rganos p\u00e9lvicos suele ser causado por el embarazo y el parto. La obesidad, la vejez y las afecciones con tos frecuente tambi\u00e9n son factores de riesgo para desarrollar la afecci\u00f3n. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> . <\/p>\n\n

\"Resultados<\/a><\/figure>\n\n

VARIANTES ANALIZADAS:<\/strong> rs3820282 rs9306894 rs1430191 rs3791675 rs7682992 rs72624976 rs1247943 rs12325192<\/p>\n\n

RECURSOS ADICIONALES:<\/strong>Prolapso p\u00e9lvico<\/a>Estr\u00f3geno<\/a> <\/a>V\u00eddeo<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 31 de marzo de 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: La asociaci\u00f3n de todo el genoma identifica siete loci para el prolapso de \u00f3rganos p\u00e9lvicos en Islandia y el Biobanco del Reino Unido RESUMEN: Identificaci\u00f3n de 8 variantes gen\u00e9ticas asociadas al prolapso de \u00f3rganos p\u00e9lvicos. VISI\u00d3N GENERAL: …<\/p>\n

Prolapso de \u00f3rganos p\u00e9lvicos (Olafsdottir, 2020)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6024,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-10814","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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