{"id":9909,"date":"2021-01-06T00:02:51","date_gmt":"2021-01-06T05:02:51","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-del-glaucoma-macgregor-2018\/"},"modified":"2021-02-20T20:40:30","modified_gmt":"2021-02-21T01:40:30","slug":"genetica-del-glaucoma-macgregor-2018","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/es\/genetica-del-glaucoma-macgregor-2018\/","title":{"rendered":"Glaucoma (MacGregor, 2018)"},"content":{"rendered":"\n

T\u00cdTULO DEL ESTUDIO:<\/strong> El estudio de asociaci\u00f3n de todo el genoma de la presi\u00f3n intraocular descubre nuevas v\u00edas hacia el glaucoma<\/a><\/p>\n\n

RESUMEN:<\/strong> Identificaci\u00f3n de m\u00e1s de 24 variantes gen\u00e9ticas que se correlacionan con el desarrollo de glaucoma.<\/p>\n\n

DESCRIPCI\u00d3N:<\/strong> El glaucoma es una de las principales causas de ceguera en los adultos mayores, aunque puede ocurrir a cualquier edad. Se desarrolla cuando el nervio \u00f3ptico que conecta el ojo con el cerebro se da\u00f1a, a menudo como resultado del aumento de la presi\u00f3n dentro del ojo. Un m\u00e9todo para detener la progresi\u00f3n del glaucoma es disminuir esa presi\u00f3n. Este estudio de asociaci\u00f3n de todo el genoma de m\u00e1s de 130.000 participantes de ascendencia europea identific\u00f3 24 variantes gen\u00e9ticas asociadas con un aumento de la presi\u00f3n intraocular y el riesgo de desarrollar esta afecci\u00f3n. Dos de las variantes se encuentran cerca de genes que desempe\u00f1an un papel en el desarrollo y la funci\u00f3n del nervio \u00f3ptico (CDKN2B y SIX6).<\/p>\n\n

\u00bfSAB\u00cdAS?<\/strong> Si bien el da\u00f1o causado por esta afecci\u00f3n no se puede revertir, la detecci\u00f3n temprana puede ayudar a retrasar la progresi\u00f3n de la p\u00e9rdida de la visi\u00f3n. Los ex\u00e1menes oculares regulares pueden detectar un aumento de la presi\u00f3n intraocular antes de que la visi\u00f3n se vea afectada. [ FUENTE<\/a> ]<\/p>\n\n

RESULTADOS DE LA MUESTRA:<\/strong> M\u00e1s informaci\u00f3n sobre el Biblioteca de investigaci\u00f3n de nebulosa<\/a> .<\/p>\n\n

\"Ejemplo<\/a><\/figure>\n\n

VARIANTES ASOCIADAS A GLAUCOMA:<\/strong> rs7518099, rs944801, rs2472493, rs2093210, rs9913911, rs28795989, rs945686, rs2745572, rs9284802, rs58073046, rs12699251, rs10505100, rs2024211, rs9853115, rs61394862, rs2935057, rs2073006, rs61861119, rs8141433, rs4141671, rs73174345, rs1013278, rs7924522, rs11710139<\/p>\n\n

RECURSOS ADICIONALES:<\/strong> Presi\u00f3n intraocular (ojo)<\/a><\/a>\u00bfQu\u00e9 es esta enfermedad?<\/a><\/p>\n\n

ACTUALIZACI\u00d3N SEMANAL:<\/strong> 24 de octubre de 2019<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DEL ESTUDIO: El estudio de asociaci\u00f3n de todo el genoma de la presi\u00f3n intraocular descubre nuevas v\u00edas hacia el glaucoma RESUMEN: Identificaci\u00f3n de m\u00e1s de 24 variantes gen\u00e9ticas que se correlacionan con el desarrollo de glaucoma. DESCRIPCI\u00d3N: El glaucoma …<\/p>\n

Glaucoma (MacGregor, 2018)<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5744,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4982],"tags":[],"class_list":["post-9909","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informes"],"yoast_head":"\nLa 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