{"id":10019,"date":"2021-01-06T00:05:38","date_gmt":"2021-01-06T05:05:38","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-de-taupes-falchi-2009\/"},"modified":"2021-02-20T20:27:02","modified_gmt":"2021-02-21T01:27:02","slug":"genetique-de-taupes-falchi-2009","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/","title":{"rendered":"Taupes (Falchi, 2009)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> Une \u00e9tude d’association \u00e0 l’\u00e9chelle du g\u00e9nome identifie les variantes \u00e0 9p21 et 22q13 associ\u00e9es au d\u00e9veloppement de naevus cutan\u00e9s<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification de 2 r\u00e9gions g\u00e9nomiques associ\u00e9es au nombre de grains de beaut\u00e9 sur le corps. <\/p>\n\n

APER\u00c7U:<\/strong> Les grains de beaut\u00e9 sont des l\u00e9sions cutan\u00e9es pigment\u00e9es, se d\u00e9veloppant g\u00e9n\u00e9ralement \u00e0 l’\u00e2ge adulte dans les zones de la peau expos\u00e9es au soleil. Dans la plupart des cas, les grains de beaut\u00e9 sont b\u00e9nins et ne n\u00e9cessitent pas de traitement. Cependant, ils se transforment parfois en cancer de la peau. Le nombre de grains de beaut\u00e9 sur le corps est le facteur de risque connu le plus important de m\u00e9lanome, un type de cancer qui se d\u00e9veloppe \u00e0 partir de cellules productrices de pigment. Cette \u00e9tude a examin\u00e9 la pr\u00e9disposition g\u00e9n\u00e9tique \u00e0 d\u00e9velopper des grains de beaut\u00e9 en examinant les g\u00e9nomes de plus de 1500 individus d’origine europ\u00e9enne. L’\u00e9tude a d\u00e9couvert 2 r\u00e9gions g\u00e9nomiques significativement associ\u00e9es \u00e0 ce trait. Les variantes g\u00e9n\u00e9tiques dans ces r\u00e9gions ont \u00e9galement \u00e9t\u00e9 directement li\u00e9es au m\u00e9lanome dans des \u00e9tudes ant\u00e9rieures. <\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> La plupart des gens ont 10 \u00e0 40 grains de beaut\u00e9. Ils peuvent changer d’apparence ou dispara\u00eetre avec le temps. Les changements hormonaux de l’adolescence et de la grossesse peuvent les faire devenir plus sombres et plus grandes. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"résultats<\/a><\/figure>\n\n

VARIANTES ASSOCI\u00c9ES \u00c0 L’\u00c9TUDE:<\/strong> rs4636294, rs2284063<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Signes d’avertissement de m\u00e9lanome<\/a>Les 4 \u00e9tapes du m\u00e9lanome (Vid\u00e9o)<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 28 avril 2020<\/p>\n\n

Jetez \u00e9galement un \u0153il \u00e0 notre Revue de curologie<\/a> !<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: Une \u00e9tude d’association \u00e0 l’\u00e9chelle du g\u00e9nome identifie les variantes \u00e0 9p21 et 22q13 associ\u00e9es au d\u00e9veloppement de naevus cutan\u00e9s SOMMAIRE: Identification de 2 r\u00e9gions g\u00e9nomiques associ\u00e9es au nombre de grains de beaut\u00e9 sur le corps. APER\u00c7U: …<\/p>\n

Taupes (Falchi, 2009)<\/span> Lire la suite \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6285,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4984],"tags":[],"class_list":["post-10019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapports"],"yoast_head":"\nLa g\u00e9n\u00e9tique du d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009)<\/title>\n<meta name=\"description\" content=\"T\u00e9l\u00e9chargez vos donn\u00e9es ADN, explorez les variantes g\u00e9n\u00e9tiques li\u00e9es au d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009) et d\u00e9couvrez votre score polyg\u00e9nique.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La g\u00e9n\u00e9tique du d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009)\" \/>\n<meta property=\"og:description\" content=\"T\u00e9l\u00e9chargez vos donn\u00e9es ADN, explorez les variantes g\u00e9n\u00e9tiques li\u00e9es au d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009) et d\u00e9couvrez votre score polyg\u00e9nique.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-06T05:05:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-02-21T01:27:02+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/04\/chris-slupski-ckMxc3LxhMo-unsplash-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Taupes (Falchi, 2009)\",\"datePublished\":\"2021-01-06T05:05:38+00:00\",\"dateModified\":\"2021-02-21T01:27:02+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\"},\"wordCount\":302,\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#organization\"},\"articleSection\":[\"Rapports\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\",\"url\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\",\"name\":\"La g\u00e9n\u00e9tique du d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009)\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#website\"},\"datePublished\":\"2021-01-06T05:05:38+00:00\",\"dateModified\":\"2021-02-21T01:27:02+00:00\",\"description\":\"T\u00e9l\u00e9chargez vos donn\u00e9es ADN, explorez les variantes g\u00e9n\u00e9tiques li\u00e9es au d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009) et d\u00e9couvrez votre score polyg\u00e9nique.\",\"breadcrumb\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nebula.org\/blog\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Taupes (Falchi, 2009)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#website\",\"url\":\"https:\/\/nebula.org\/blog\/fr\/\",\"name\":\"Nebula Genomics Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nebula.org\/blog\/fr\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#organization\",\"name\":\"Nebula Genomics\",\"url\":\"https:\/\/nebula.org\/blog\/fr\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Nebula Genomics\"},\"image\":{\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/facebook.com\/nebulagenomics\",\"https:\/\/twitter.com\/nebulagenomics\",\"https:\/\/www.instagram.com\/nebulagenomics\/\",\"https:\/\/www.linkedin.com\/company\/nebula-genomics\/\",\"https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\",\"name\":\"Garrett Dunlap, B.S.\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/nebula.org\/blog\/fr\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"caption\":\"Garrett Dunlap, B.S.\"},\"description\":\"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.\",\"sameAs\":[\"https:\/\/nebula.org\/whole-genome-sequencing\/\"],\"url\":\"https:\/\/nebula.org\/blog\/fr\/author\/garrett-dunlap\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"La g\u00e9n\u00e9tique du d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009)","description":"T\u00e9l\u00e9chargez vos donn\u00e9es ADN, explorez les variantes g\u00e9n\u00e9tiques li\u00e9es au d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009) et d\u00e9couvrez votre score polyg\u00e9nique.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/","og_locale":"fr_FR","og_type":"article","og_title":"La g\u00e9n\u00e9tique du d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009)","og_description":"T\u00e9l\u00e9chargez vos donn\u00e9es ADN, explorez les variantes g\u00e9n\u00e9tiques li\u00e9es au d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009) et d\u00e9couvrez votre score polyg\u00e9nique.","og_url":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/","og_site_name":"Nebula Genomics Blog","article_publisher":"https:\/\/facebook.com\/nebulagenomics","article_published_time":"2021-01-06T05:05:38+00:00","article_modified_time":"2021-02-21T01:27:02+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/04\/chris-slupski-ckMxc3LxhMo-unsplash-scaled.jpg","type":"image\/jpeg"}],"author":"Garrett Dunlap, B.S.","twitter_card":"summary_large_image","twitter_creator":"@nebulagenomics","twitter_site":"@nebulagenomics","twitter_misc":{"\u00c9crit par":"Garrett Dunlap, B.S.","Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/#article","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/"},"author":{"name":"Garrett Dunlap, B.S.","@id":"https:\/\/nebula.org\/blog\/fr\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e"},"headline":"Taupes (Falchi, 2009)","datePublished":"2021-01-06T05:05:38+00:00","dateModified":"2021-02-21T01:27:02+00:00","mainEntityOfPage":{"@id":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/"},"wordCount":302,"publisher":{"@id":"https:\/\/nebula.org\/blog\/fr\/#organization"},"articleSection":["Rapports"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/","url":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/","name":"La g\u00e9n\u00e9tique du d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009)","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/fr\/#website"},"datePublished":"2021-01-06T05:05:38+00:00","dateModified":"2021-02-21T01:27:02+00:00","description":"T\u00e9l\u00e9chargez vos donn\u00e9es ADN, explorez les variantes g\u00e9n\u00e9tiques li\u00e9es au d\u00e9veloppement des grains de beaut\u00e9 (Falchi, 2009) et d\u00e9couvrez votre score polyg\u00e9nique.","breadcrumb":{"@id":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nebula.org\/blog\/fr\/genetique-de-taupes-falchi-2009\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nebula.org\/blog\/fr\/"},{"@type":"ListItem","position":2,"name":"Taupes (Falchi, 2009)"}]},{"@type":"WebSite","@id":"https:\/\/nebula.org\/blog\/fr\/#website","url":"https:\/\/nebula.org\/blog\/fr\/","name":"Nebula Genomics Blog","description":"","publisher":{"@id":"https:\/\/nebula.org\/blog\/fr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nebula.org\/blog\/fr\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/nebula.org\/blog\/fr\/#organization","name":"Nebula Genomics","url":"https:\/\/nebula.org\/blog\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/nebula.org\/blog\/fr\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Nebula Genomics"},"image":{"@id":"https:\/\/nebula.org\/blog\/fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/facebook.com\/nebulagenomics","https:\/\/twitter.com\/nebulagenomics","https:\/\/www.instagram.com\/nebulagenomics\/","https:\/\/www.linkedin.com\/company\/nebula-genomics\/","https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics"]},{"@type":"Person","@id":"https:\/\/nebula.org\/blog\/fr\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e","name":"Garrett Dunlap, B.S.","image":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/nebula.org\/blog\/fr\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","caption":"Garrett Dunlap, B.S."},"description":"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/fr\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/posts\/10019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/comments?post=10019"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/posts\/10019\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/media\/6285"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/media?parent=10019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/categories?post=10019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/fr\/wp-json\/wp\/v2\/tags?post=10019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}