{"id":10048,"date":"2021-01-06T00:06:19","date_gmt":"2021-01-06T05:06:19","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-minceur-orthofer-2020\/"},"modified":"2021-02-20T20:28:07","modified_gmt":"2021-02-21T01:28:07","slug":"genetique-minceur-orthofer-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-minceur-orthofer-2020\/","title":{"rendered":"Minceur (Orthofer, 2020)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> Identification de l’ALK dans la minceur<\/a><\/p>\n\n

SOMMAIRE:<\/strong> D\u00e9couverte de 5 variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 la minceur.<\/p>\n\n

APER\u00c7U:<\/strong> Bien que le r\u00e9gime alimentaire et l’exercice soient importants pour maintenir un poids corporel sain, les personnes qui mangent des aliments similaires et font de l’exercice en quantit\u00e9s similaires peuvent diff\u00e9rer par leur poids. La plupart des \u00e9tudes qui recherchent des variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 l’indice de masse corporelle (IMC) comparent les personnes ob\u00e8ses \u00e0 des t\u00e9moins sains. Cette \u00e9tude a plut\u00f4t cherch\u00e9 des associations avec la minceur. Les chercheurs ont compar\u00e9 les 1,9% de personnes les plus maigres (6e percentile d’IMC; 881 individus) dans la biobanque estonienne avec des personnes qui avaient un poids corporel moyen (30e \u00e0 50e percentile d’IMC; 3173 personnes) et ont trouv\u00e9 5 variantes associ\u00e9es \u00e0 la minceur. L’une des variantes (rs568057364) se trouve \u00e0 l’int\u00e9rieur du g\u00e8ne ALK qui est connu pour jouer un r\u00f4le dans le cancer. Les chercheurs ont perturb\u00e9 le g\u00e8ne ALK chez la souris et ont d\u00e9couvert qu’il entra\u00eenait une r\u00e9sistance \u00e0 l’ob\u00e9sit\u00e9 induite par l’alimentation.<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> Les personnes souffrant d’insuffisance pond\u00e9rale ont souvent des carences nutritionnelles parce qu’elles ne consomment pas suffisamment de nourriture pour recevoir toutes les vitamines et tous les min\u00e9raux dont leur corps a besoin. Il est important d’obtenir suffisamment de micronutriments, m\u00eame en limitant l’apport calorique. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"résultats<\/a><\/figure>\n\n

VARIANTES ASSOCI\u00c9ES \u00c0 LA MINCEUR:<\/strong> rs6574213, rs79938778, rs61685635, rs568057364, rs4521442<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Perte de poids et indice de masse corporelle (vid\u00e9o)<\/a>Calculateur IMC<\/a><\/p>\n\n

VOUS POUVEZ \u00c9GALEMENT \u00caTRE INT\u00c9RESS\u00c9 PAR:<\/strong> Poids \u00e0 la naissance et sensibilit\u00e9 aux maladies (Horikoshi, 2017)<\/a>Indice de masse corporelle (Couto Alves, 2019)<\/a>Indice de masse corporelle (Anderson, 2020)<\/a>Ob\u00e9sit\u00e9 (Jiao, 2011)<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 16 juin 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: Identification de l’ALK dans la minceur SOMMAIRE: D\u00e9couverte de 5 variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 la minceur. APER\u00c7U: Bien que le r\u00e9gime alimentaire et l’exercice soient importants pour maintenir un poids corporel sain, les personnes qui mangent des …<\/p>\n

Minceur (Orthofer, 2020)<\/span> Lire la suite 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