{"id":10139,"date":"2021-01-06T00:08:13","date_gmt":"2021-01-06T05:08:13","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-carcinome-epidermoide-pulmonaire-mckay-2017\/"},"modified":"2021-02-20T20:27:26","modified_gmt":"2021-02-21T01:27:26","slug":"genetique-carcinome-epidermoide-pulmonaire-mckay-2017","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-carcinome-epidermoide-pulmonaire-mckay-2017\/","title":{"rendered":"Carcinome pulmonaire \u00e9pidermo\u00efde (McKay, 2017)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> Une analyse d’association \u00e0 grande \u00e9chelle identifie de nouveaux loci de susceptibilit\u00e9 au cancer du poumon et une h\u00e9t\u00e9rog\u00e9n\u00e9it\u00e9 de la susceptibilit\u00e9 g\u00e9n\u00e9tique \u00e0 travers les sous-types histologiques<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification de 3 r\u00e9gions g\u00e9nomiques associ\u00e9es au carcinome \u00e9pidermo\u00efde du poumon. <\/p>\n\n

APER\u00c7U:<\/strong> Le cancer du poumon est une maladie dans laquelle les cellules des poumons se divisent de mani\u00e8re incontr\u00f4lable. Les cellules squameuses sont des cellules de forme plate qui tapissent de nombreux organes du corps. Le carcinome \u00e9pidermo\u00efde du poumon (SCLC) est un type de cancer du poumon caus\u00e9 par des mutations dans les cellules squameuses qui tapissent les voies respiratoires des poumons. Ce sous-type de cancer du poumon repr\u00e9sente 30% de tous les cas de cancer du poumon et est souvent li\u00e9 \u00e0 des ant\u00e9c\u00e9dents de tabagisme. Afin de comprendre la base g\u00e9n\u00e9tique du SCLC, les chercheurs ont examin\u00e9 les g\u00e9nomes d’environ 63 000 individus. Ils ont identifi\u00e9 3 r\u00e9gions g\u00e9nomiques associ\u00e9es au SCLC. En plus, ces variantes g\u00e9n\u00e9tiques expliquent environ 6,2% de l’h\u00e9ritabilit\u00e9 du SCLC. <\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> Le type de cancer du poumon le plus courant chez les hommes est le carcinome \u00e9pidermo\u00efde. Ce sous-type de cancer du poumon est souvent plus facile \u00e0 d\u00e9tecter car il produit plus de sympt\u00f4mes que les autres sous-types de cancer du poumon. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"résultats<\/a><\/figure>\n\n

VARIANTES ASSOCIES AU SCLC:<\/strong> rs116822326, rs17879961, rs7953330<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Cancer du poumon (vid\u00e9o)<\/a>Types de cancer du poumon<\/a>Carcinome \u00e9pidermo\u00efde du poumon<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 12 mai 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: Une analyse d’association \u00e0 grande \u00e9chelle identifie de nouveaux loci de susceptibilit\u00e9 au cancer du poumon et une h\u00e9t\u00e9rog\u00e9n\u00e9it\u00e9 de la susceptibilit\u00e9 g\u00e9n\u00e9tique \u00e0 travers les sous-types histologiques SOMMAIRE: Identification de 3 r\u00e9gions g\u00e9nomiques associ\u00e9es au carcinome …<\/p>\n

Carcinome pulmonaire \u00e9pidermo\u00efde (McKay, 2017)<\/span> Lire la suite \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6345,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4984],"tags":[],"class_list":["post-10139","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapports"],"yoast_head":"\nLa 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