{"id":10266,"date":"2021-01-06T00:12:36","date_gmt":"2021-01-06T05:12:36","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-inflammatoire-proteine-hillary-2020\/"},"modified":"2021-02-20T20:42:32","modified_gmt":"2021-02-21T01:42:32","slug":"genetique-inflammatoire-proteine-hillary-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-inflammatoire-proteine-hillary-2020\/","title":{"rendered":"Niveau de prot\u00e9ine inflammatoire (Hillary, 2020)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> \u00c9tudes multi-m\u00e9thodes \u00e0 l’\u00e9chelle du g\u00e9nome et de l’\u00e9pig\u00e9nome des niveaux de prot\u00e9ines inflammatoires chez les personnes \u00e2g\u00e9es en bonne sant\u00e9<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification de 16 variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 la pr\u00e9sence de prot\u00e9ines inflammatoires dans le sang.<\/p>\n\n

APER\u00c7U:<\/strong> L’inflammation est une r\u00e9ponse du syst\u00e8me immunitaire \u00e0 une infection ou \u00e0 une blessure. Elle est caus\u00e9e par une lib\u00e9ration de prot\u00e9ines inflammatoires qui attirent les cellules immunitaires pour combattre l’infection et augmentent le flux sanguin pour favoriser la gu\u00e9rison. Cependant, parfois, ces signaux favorisant l’inflammation peuvent se produire et persister m\u00eame lorsqu’ils ne sont pas n\u00e9cessaires et causer des dommages au corps. Cette \u00e9tude a examin\u00e9 les niveaux de prot\u00e9ines inflammatoires dans le sang et a trouv\u00e9 16 variantes g\u00e9n\u00e9tiques associ\u00e9es. Ces variantes expliquaient jusqu’\u00e0 45% de la variance de ces niveaux. L’\u00e9tude a \u00e9galement li\u00e9 certaines des prot\u00e9ines inflammatoires \u00e0 des maladies sp\u00e9cifiques, notamment la maladie de Crohn, l’hypertension art\u00e9rielle et la maladie d’Alzheimer.<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> L’inflammation chronique peut \u00eatre r\u00e9duite par un r\u00e9gime anti-inflammatoire. Cela comprend la consommation d’aliments riches en acides gras om\u00e9ga-3, en antioxydants, en probiotiques et en fibres et en \u00e9vitant les aliments riches en gras trans, en gras satur\u00e9s et en acides gras om\u00e9ga-6. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"résultats<\/a><\/figure>\n\n

VARIANTES ASSOCI\u00c9ES AU NIVEAU DE PROT\u00c9INES INFLAMMATOIRES:<\/strong> rs3138036, rs12075, rs2032887, rs2272128, rs11700291, rs2229092, rs6138139, rs1458038, rs6603134, rs10045431, rs11230563, rs485186, rs10005565, rs485186, rs10005565, rs1333565<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Inflammation chronique (vid\u00e9o)<\/a>Comprendre l’inflammation aigu\u00eb et chronique<\/a><\/p>\n\n

VOUS POUVEZ \u00c9GALEMENT \u00caTRE INT\u00c9RESS\u00c9 PAR:<\/strong> Marqueurs d’inflammation dans le sang (Ligthart, 2018)<\/a>Maladie de Crohn (Franke, 2010)<\/a>Maladie d’Alzheimer (Kunkle, 2019)<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 21 juillet 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: \u00c9tudes multi-m\u00e9thodes \u00e0 l’\u00e9chelle du g\u00e9nome et de l’\u00e9pig\u00e9nome des niveaux de prot\u00e9ines inflammatoires chez les personnes \u00e2g\u00e9es en bonne sant\u00e9 SOMMAIRE: Identification de 16 variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 la pr\u00e9sence de prot\u00e9ines inflammatoires dans le sang. …<\/p>\n

Niveau de prot\u00e9ine inflammatoire (Hillary, 2020)<\/span> Lire la suite 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