{"id":10273,"date":"2021-01-06T00:21:39","date_gmt":"2021-01-06T05:21:39","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetics-of-healthspan-timmers-2020\/"},"modified":"2021-02-20T20:26:24","modified_gmt":"2021-02-21T01:26:24","slug":"genetics-of-healthspan-timmers-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetics-of-healthspan-timmers-2020\/","title":{"rendered":"Healthspan (Timmers, 2020)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> L’analyse g\u00e9nomique multivari\u00e9e implique de nouveaux loci et le m\u00e9tabolisme de l’h\u00e8me dans le vieillissement humain<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification de 10 variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 healthspan, ou le nombre d’ann\u00e9es en bonne sant\u00e9.<\/p>\n\n

APER\u00c7U:<\/strong> Le vieillissement fait partie int\u00e9grante de la vie. M\u00eame si nous voulons tous vivre plus longtemps, nous ne voulons pas que nos derni\u00e8res ann\u00e9es soient d\u00e9finies par la maladie. Bien que de nombreuses personnes connaissent la \u00abdur\u00e9e de vie\u00bb ou la dur\u00e9e de vie d’une personne, moins connaissent le terme \u00absant\u00e9\u00bb. Healthspan fait r\u00e9f\u00e9rence \u00e0 la dur\u00e9e pendant laquelle une personne vit en bonne sant\u00e9, sans maladies chroniques g\u00e9n\u00e9ralement associ\u00e9es au vieillissement. Ceux-ci comprennent les maladies cardiaques, la maladie d’Alzheimer, le diab\u00e8te et diverses formes de cancer. Alors que la dur\u00e9e de vie moyenne aux \u00c9tats-Unis est d’environ 79 ans, la dur\u00e9e de vie moyenne n’est que de 63 ans. Pour identifier les facteurs g\u00e9n\u00e9tiques associ\u00e9s \u00e0 healthspan, cette \u00e9tude d’association \u00e0 l’\u00e9chelle du g\u00e9nome a examin\u00e9 plus de 300 000 individus d’ascendance europ\u00e9enne. L’\u00e9tude a trouv\u00e9 10 variantes g\u00e9n\u00e9tiques, qui influencent non seulement la sant\u00e9, mais aussi la dur\u00e9e de vie et la long\u00e9vit\u00e9 des parents.<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> Les choix alimentaires plus t\u00f4t dans la vie sont importants pour un vieillissement en sant\u00e9. Le maintien d’un poids corporel sain et la satisfaction des besoins nutritionnels r\u00e9duisent le risque de nombreuses maladies chroniques. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"résultats<\/a><\/figure>\n\n

VARIANTES ASSOCI\u00c9ES \u00c0 LA SANT\u00c9:<\/strong> rs429358, rs10455872, rs7859727, rs61905747, rs6511720, rs12830425, rs1159806, rs4783780, rs2643826, rs17499404<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong><\/a>La science du vieillissement (vid\u00e9o)<\/a><\/p>\n\n

VOUS POUVEZ \u00c9GALEMENT \u00caTRE INT\u00c9RESS\u00c9 PAR:<\/strong> Long\u00e9vit\u00e9 (Deelen, 2019)<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 28 juillet 2020<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: L’analyse g\u00e9nomique multivari\u00e9e implique de nouveaux loci et le m\u00e9tabolisme de l’h\u00e8me dans le vieillissement humain SOMMAIRE: Identification de 10 variantes g\u00e9n\u00e9tiques associ\u00e9es \u00e0 healthspan, ou le nombre d’ann\u00e9es en bonne sant\u00e9. APER\u00c7U: Le vieillissement fait partie …<\/p>\n

Healthspan (Timmers, 2020)<\/span> Lire la suite \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6655,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4984],"tags":[],"class_list":["post-10273","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapports"],"yoast_head":"\nLa 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