{"id":10518,"date":"2021-01-06T00:29:43","date_gmt":"2021-01-06T05:29:43","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-du-diabete-de-type-2-cuisinier-2016\/"},"modified":"2021-02-20T20:55:57","modified_gmt":"2021-02-21T01:55:57","slug":"genetique-du-diabete-de-type-2-cuisinier-2016","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-du-diabete-de-type-2-cuisinier-2016\/","title":{"rendered":"Diab\u00e8te de type 2 (Cook, 2016)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> Une \u00e9tude d’association multiethnique \u00e0 l’\u00e9chelle du g\u00e9nome identifie un nouveau locus pour la susceptibilit\u00e9 au diab\u00e8te de type 2<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification d’un nouveau locus g\u00e9n\u00e9tique associ\u00e9 au risque de d\u00e9velopper un diab\u00e8te de type 2.<\/p>\n\n

APER\u00c7U:<\/strong> Le glucose, \u00e9galement connu sous le nom de sucre dans le sang, se trouve dans de nombreux aliments courants. L’insuline, une hormone produite par le pancr\u00e9as, aide les cellules du corps \u00e0 absorber le glucose du sang et \u00e0 l’utiliser comme source d’\u00e9nergie. Le diab\u00e8te de type 2 (DT2) survient lorsque le pancr\u00e9as ne produit pas suffisamment d’insuline ou lorsque les cellules du corps ne r\u00e9pondent pas \u00e0 l’insuline. Cela entra\u00eene une glyc\u00e9mie \u00e9lev\u00e9e qui peut endommager les nerfs, les vaisseaux sanguins, les reins et d’autres organes. Si les facteurs environnementaux, en particulier l’alimentation, sont des facteurs de risque de DT2, une sensibilit\u00e9 peut \u00e9galement \u00eatre h\u00e9rit\u00e9e. Cette \u00e9tude multiethnique \u00e0 l’\u00e9chelle du g\u00e9nome de plus de 71 000 individus a identifi\u00e9 un nouveau locus associ\u00e9 au risque de d\u00e9velopper un DT2, portant le nombre total de locus connus \u00e0 10. La nouvelle variante est proche de la APOE<\/a> g\u00e8ne, qui aide \u00e0 transporter les graisses dans le sang. L’APOE a \u00e9t\u00e9 pr\u00e9c\u00e9demment associ\u00e9e \u00e0 plusieurs autres troubles, y compris la maladie d’Alzheimer.<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> On estime que 80% de tous les cas de diab\u00e8te de type 2 peuvent \u00eatre \u00e9vit\u00e9s en adoptant un mode de vie plus sain. Cela peut \u00eatre r\u00e9alis\u00e9 gr\u00e2ce \u00e0 une combinaison de changements alimentaires (comme moins de graisses satur\u00e9es et plus de fibres) et une activit\u00e9 physique accrue. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"Résultats<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ASSOCI\u00c9ES AU T2D:<\/strong> rs34872471, rs11927381, rs849134, rs13266634, rs7766070, rs10811661, rs9273401, rs3768321, rs157582, rs9687833<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Diab\u00e8te de type 2 (vid\u00e9o)<\/a>APOE<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 19 d\u00e9cembre 2019<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: Une \u00e9tude d’association multiethnique \u00e0 l’\u00e9chelle du g\u00e9nome identifie un nouveau locus pour la susceptibilit\u00e9 au diab\u00e8te de type 2 SOMMAIRE: Identification d’un nouveau locus g\u00e9n\u00e9tique associ\u00e9 au risque de d\u00e9velopper un diab\u00e8te de type 2. APER\u00c7U: …<\/p>\n

Diab\u00e8te de type 2 (Cook, 2016)<\/span> Lire la suite \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5430,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4984],"tags":[],"class_list":["post-10518","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapports"],"yoast_head":"\nLa 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