{"id":10785,"date":"2021-01-06T00:35:15","date_gmt":"2021-01-06T05:35:15","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-of-sars-coronavirus-infection-ching-2010\/"},"modified":"2021-02-20T20:52:19","modified_gmt":"2021-02-21T01:52:19","slug":"genetique-of-sars-coronavirus-infection-ching-2010","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-of-sars-coronavirus-infection-ching-2010\/","title":{"rendered":"Infection \u00e0 coronavirus du SRAS (Ching, 2010)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> Importance du g\u00e8ne Myxovirus Resistance A (MxA) – 123C> Polymorphisme \u00e0 un seul nucl\u00e9otide dans l’induction par l’interf\u00e9ron \u03b2 supprim\u00e9e d’une infection \u00e0 coronavirus du syndrome respiratoire aigu s\u00e9v\u00e8re<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification d’une variante g\u00e9n\u00e9tique associ\u00e9e \u00e0 une diminution du risque de SRAS coronavirus<\/em> infection.<\/p>\n\n

APER\u00c7U:<\/strong> Le syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS) coronavirus<\/em> a \u00e9merg\u00e9 en 2003 en Chine. En un peu plus d’un an, il a infect\u00e9 8 000 personnes et caus\u00e9 plus de 900 d\u00e9c\u00e8s dans le monde. Les sympt\u00f4mes typiques comprennent une forte fi\u00e8vre, des maux de t\u00eate et une toux s\u00e8che. Des \u00e9tudes ant\u00e9rieures ont montr\u00e9 que interf\u00e9rons<\/em> peut inhiber la r\u00e9plication du SRAS coronavirus<\/em> en induisant la production de prot\u00e9ines antivirales comme MxA. Cette \u00e9tude a d\u00e9montr\u00e9 qu’une variante g\u00e9n\u00e9tique (rs17000900) proche du g\u00e8ne MxA influence son activit\u00e9 lorsque les cellules sont expos\u00e9es \u00e0 interf\u00e9rons<\/em> . L’\u00e9tude a \u00e9galement examin\u00e9 les informations g\u00e9n\u00e9tiques de plus de 1200 personnes d’origine chinoise et a \u00e9tabli une relation entre cette variante g\u00e9n\u00e9tique et le risque de SRAS. coronavirus<\/em> infection. Les r\u00e9sultats sugg\u00e8rent que l’all\u00e8le A du variant rs17000900 est li\u00e9 \u00e0 une diminution de la sensibilit\u00e9 au SRAS coronavirus<\/em> infection. (Remarque: cette \u00e9tude n’est pas une \u00e9tude d’association \u00e0 l’\u00e9chelle du g\u00e9nome. Seules quelques variantes ont \u00e9t\u00e9 g\u00e9notyp\u00e9es de mani\u00e8re s\u00e9lective.)<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> Les coronavirus sont \u00e9galement responsables de la pand\u00e9mie de MERS (syndrome respiratoire du Moyen-Orient) au d\u00e9but des ann\u00e9es 2010. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"Résultats<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ANALYS\u00c9ES DU CORONAVIRUS DU SRAS:<\/strong> rs17000900<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS)<\/a>Le\u00e7on tir\u00e9e de l’\u00e9pid\u00e9mie de SRAS (vid\u00e9o)<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 23 mars 2020<\/p>\n\n

Pour des mises \u00e0 jour sur la g\u00e9n\u00e9tique du COVID-19, visitez: https:\/\/nebula.org\/blog\/category\/science\/<\/a><\/p>\n\n

Vous pouvez en savoir plus sur tests de coronavirus \u00e0 domicile<\/a> dans notre revue!<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: Importance du g\u00e8ne Myxovirus Resistance A (MxA) – 123C> Polymorphisme \u00e0 un seul nucl\u00e9otide dans l’induction par l’interf\u00e9ron \u03b2 supprim\u00e9e d’une infection \u00e0 coronavirus du syndrome respiratoire aigu s\u00e9v\u00e8re SOMMAIRE: Identification d’une variante g\u00e9n\u00e9tique associ\u00e9e \u00e0 une …<\/p>\n

Infection \u00e0 coronavirus du SRAS (Ching, 2010)<\/span> Lire la suite \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5935,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4984],"tags":[],"class_list":["post-10785","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapports"],"yoast_head":"\nLa 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