{"id":10788,"date":"2021-01-06T00:35:18","date_gmt":"2021-01-06T05:35:18","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetique-of-sars-coronavirus-infection-hamano-2005\/"},"modified":"2021-02-20T20:57:10","modified_gmt":"2021-02-21T01:57:10","slug":"genetique-of-sars-coronavirus-infection-hamano-2005","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/genetique-of-sars-coronavirus-infection-hamano-2005\/","title":{"rendered":"Infection \u00e0 coronavirus du SRAS (Hamano, 2005)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> Polymorphismes des g\u00e8nes inductibles par l’interf\u00e9ron OAS-1 et MxA associ\u00e9s au SRAS dans la population vietnamienne<\/a><\/p>\n\n

SOMMAIRE:<\/strong> D\u00e9couverte d’un variant g\u00e9n\u00e9tique du g\u00e8ne OAS-1 associ\u00e9 \u00e0 un risque accru de syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS) coronavirus<\/em> infection.<\/p>\n\n

APER\u00c7U:<\/strong> En 2003, syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS) coronavirus<\/em> \u00e9merg\u00e9 en Chine. Il s’est propag\u00e9 \u00e0 des pays d’Asie, d’Europe et d’Am\u00e9rique du Nord, entra\u00eenant un total d’environ 8 000 cas. Le SRAS est une maladie infectieuse qui peut provoquer des sympt\u00f4mes pseudo-grippaux, notamment de la fi\u00e8vre, de la toux et un essoufflement. Bien que plusieurs facteurs de risque cliniques de d\u00e9veloppement du SRAS, tels que le fait d’avoir plus de 60 ans ou le diab\u00e8te, aient \u00e9t\u00e9 identifi\u00e9s, on en sait peu sur la mani\u00e8re dont la g\u00e9n\u00e9tique affecte la sensibilit\u00e9 au SRAS. coronavirus<\/em> infection. Cette \u00e9tude a utilis\u00e9 les donn\u00e9es g\u00e9n\u00e9tiques de 147 individus vietnamiens, dont 60 \u00e9taient des patients atteints du SRAS, et a d\u00e9couvert une variante g\u00e9n\u00e9tique (rs2660) dans le g\u00e8ne OAS-1 qui est associ\u00e9e \u00e0 une susceptibilit\u00e9 \u00e0 l’infection par le SRAS. coronavirus<\/em> . Plus pr\u00e9cis\u00e9ment, l’all\u00e8le G du variant rs2660 \u00e9tait li\u00e9 \u00e0 une sensibilit\u00e9 accrue \u00e0 l’infection par le SRAS coronavirus<\/em> . (Remarque: cette \u00e9tude n’est pas une \u00e9tude d’association \u00e0 l’\u00e9chelle du g\u00e9nome. Seules quelques variantes ont \u00e9t\u00e9 g\u00e9notyp\u00e9es de mani\u00e8re s\u00e9lective.)<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> Le virus SRAS-CoV qui a caus\u00e9 l’\u00e9pid\u00e9mie de SRAS de 2003 est tr\u00e8s similaire au SRAS-CoV-2, responsable de la pand\u00e9mie de la maladie \u00e0 coronavirus 2019 (COVID-19). [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"résultat<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ANALYS\u00c9ES:<\/strong> rs2660<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS)<\/a>SRAS: les personnes qui ont risqu\u00e9 leur vie pour arr\u00eater le virus<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 23 mars 2020<\/p>\n\n

Pour des mises \u00e0 jour sur la g\u00e9n\u00e9tique du COVID-19, visitez: https:\/\/nebula.org\/blog\/category\/science\/<\/a><\/p>\n\n

Vous pouvez en savoir plus sur tests de coronavirus \u00e0 domicile<\/a> dans notre revue!<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: Polymorphismes des g\u00e8nes inductibles par l’interf\u00e9ron OAS-1 et MxA associ\u00e9s au SRAS dans la population vietnamienne SOMMAIRE: D\u00e9couverte d’un variant g\u00e9n\u00e9tique du g\u00e8ne OAS-1 associ\u00e9 \u00e0 un risque accru de syndrome respiratoire aigu s\u00e9v\u00e8re (SRAS) coronavirus infection. …<\/p>\n

Infection \u00e0 coronavirus du SRAS (Hamano, 2005)<\/span> Lire la suite 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