{"id":10810,"date":"2021-01-06T00:35:40","date_gmt":"2021-01-06T05:35:40","guid":{"rendered":"https:\/\/nebula.org\/blog\/prolapsus-dorgane-pelvien-olafsdottir-2020\/"},"modified":"2021-02-20T20:50:09","modified_gmt":"2021-02-21T01:50:09","slug":"prolapsus-dorgane-pelvien-olafsdottir-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/fr\/prolapsus-dorgane-pelvien-olafsdottir-2020\/","title":{"rendered":"Prolapsus des organes pelviens (Olafsdottir, 2020)"},"content":{"rendered":"\n

TITRE DE L’\u00c9TUDE:<\/strong> L’association pang\u00e9nomique identifie sept locus de prolapsus des organes pelviens en Islande et dans la biobanque britannique<\/a><\/p>\n\n

SOMMAIRE:<\/strong> Identification de 8 variantes g\u00e9n\u00e9tiques associ\u00e9es au prolapsus des organes pelviens.<\/p>\n\n

APER\u00c7U:<\/strong> Les muscles qui soutiennent les organes pelviens d’une femme peuvent s’affaiblir, ce qui fait chuter des organes comme la vessie et l’ut\u00e9rus plus bas dans le bassin<\/em> . Cette condition est appel\u00e9e prolapsus des organes pelviens, ce qui entra\u00eene des sympt\u00f4mes tels que la pression dans la r\u00e9gion pelvienne, des probl\u00e8mes intestinaux et un dysfonctionnement sexuel. Elle est tr\u00e8s courante, touchant pr\u00e8s d’une femme sur trois \u00e0 un moment donn\u00e9 de sa vie. Cette \u00e9tude d’association pang\u00e9nomique a examin\u00e9 plus de 355 000 femmes d’origine europ\u00e9enne afin de mieux comprendre les facteurs de risque g\u00e9n\u00e9tiques du prolapsus des organes pelviens. L’\u00e9tude a identifi\u00e9 8 variantes associ\u00e9es au prolapsus des organes pelviens, qui expliquent collectivement environ 12% de l’h\u00e9ritabilit\u00e9 de la maladie. L’une des variantes g\u00e9n\u00e9tiques d\u00e9couvertes semble affecter le oestrog\u00e8ne<\/em> voie de signalisation, tandis qu’une autre variante influence le maintien du tissu conjonctif dans le bassin<\/em> .<\/p>\n\n

LE SAVIEZ-VOUS?<\/strong> Le prolapsus des organes pelviens est le plus souvent caus\u00e9 par la grossesse et l’accouchement. L’ob\u00e9sit\u00e9, la vieillesse et les conditions de toux fr\u00e9quente sont \u00e9galement des facteurs de risque de d\u00e9velopper la maladie. [SOURCE]<\/a><\/p>\n\n

EXEMPLE DE R\u00c9SULTATS:<\/strong> En savoir plus sur Biblioth\u00e8que de recherche sur la n\u00e9buleuse<\/a> . <\/p>\n\n

\"Résultats<\/a><\/figure>\n\n

VARIANTES ANALYS\u00c9ES:<\/strong> rs3820282 rs9306894 rs1430191 rs3791675 rs7682992 rs72624976 rs1247943 rs12325192<\/p>\n\n

RESSOURCES ADDITIONNELLES:<\/strong>Prolapsus pelvien<\/a>\u0152strog\u00e8ne<\/a> <\/a>Vid\u00e9o<\/a><\/p>\n\n

MISE \u00c0 JOUR HEBDOMADAIRE:<\/strong> 31 mars 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

TITRE DE L’\u00c9TUDE: L’association pang\u00e9nomique identifie sept locus de prolapsus des organes pelviens en Islande et dans la biobanque britannique SOMMAIRE: Identification de 8 variantes g\u00e9n\u00e9tiques associ\u00e9es au prolapsus des organes pelviens. APER\u00c7U: Les muscles qui soutiennent les organes pelviens …<\/p>\n

Prolapsus des organes pelviens (Olafsdottir, 2020)<\/span> Lire la suite \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":6020,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4984],"tags":[],"class_list":["post-10810","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapports"],"yoast_head":"\nLa 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