{"id":10351,"date":"2021-01-06T00:26:42","date_gmt":"2021-01-06T05:26:42","guid":{"rendered":"https:\/\/nebula.org\/blog\/%e9%81%ba%e4%bc%9d%e5%ad%a6-of-mpb-pirastu-2017\/"},"modified":"2021-02-20T20:56:38","modified_gmt":"2021-02-21T01:56:38","slug":"%e9%81%ba%e4%bc%9d%e5%ad%a6-of-mpb-pirastu-2017","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/ja\/%e9%81%ba%e4%bc%9d%e5%ad%a6-of-mpb-pirastu-2017\/","title":{"rendered":"\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08Pirastu\u30012017\u5e74\uff09"},"content":{"rendered":"\n<p><strong>\u7814\u7a76\u30bf\u30a4\u30c8\u30eb\uff1a<\/strong><a href=\"https:\/\/www.nature.com\/articles\/s41467-017-01490-8\">\u7537\u6027\u578b\u8131\u6bdb\u75c7\u306eGWAS\u306f\u3001\u30ea\u30b9\u30af\u306e38\uff05\u3092\u8aac\u660e\u3059\u308b71\u306e\u611f\u53d7\u6027\u907a\u4f1d\u5b50\u5ea7\u3092\u7279\u5b9a\u3057\u307e\u3059<\/a><\/p>\n\n<p><strong>\u6982\u8981\uff1a<\/strong>\u7537\u6027\u578b\u8131\u6bdb\u75c7\u306b\u95a2\u9023\u3059\u308b71\u306e\u907a\u4f1d\u7684\u9818\u57df\u306e\u540c\u5b9a\u3002<\/p>\n\n<p><strong>\u6982\u8981\uff1a<\/strong>\u8131\u6bdb\u306f\u975e\u5e38\u306b\u4e00\u822c\u7684\u306a\u554f\u984c\u3067\u3059\u3002 \u5b9f\u969b\u300150\u6b73\u307e\u3067\u306b\u3001\u7537\u6027\u306e\u7d0450\uff05\u304c\u5927\u5e45\u306a\u8584\u6bdb\u3092\u7d4c\u9a13\u3057\u3001\u6700\u7d42\u7684\u306b\u306f\u99ac\u8e44\u5f62\u306e\u30d1\u30bf\u30fc\u30f3\u3067\u9aea\u306b\u56f2\u307e\u308c\u305f\u79bf\u3052\u305f\u9818\u57df\u306b\u306a\u308a\u307e\u3059\u3002 \u3053\u308c\u306f\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08MPB\uff09\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002 MBP\u306f\u4e00\u822c\u7684\u306a\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3042\u308a\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u30ec\u30d9\u30eb\u306b\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u524d\u7acb\u817a\u304c\u3093\u3001\u5fc3\u81d3\u75c5\u3001\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u5897\u52a0\u306a\u3069\u306e\u6df1\u523b\u306a\u5065\u5eb7\u72b6\u614b\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u3088\u304f\u3042\u308a\u307e\u3059\u3002 \u305f\u3060\u3057\u3001MPB\u306e\u6839\u5e95\u306b\u3042\u308b\u907a\u4f1d\u7684\u57fa\u76e4\u306f\u3088\u304f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u307e\u307e\u3067\u3059\u3002 70,000\u4eba\u4ee5\u4e0a\u306e\u7537\u6027\u306e\u30b2\u30ce\u30e0\u3092\u8abf\u3079\u305f\u3053\u306e\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u7814\u7a76\u3002 \u3053\u306e\u7814\u7a76\u3067\u306f\u300171\u306e\u907a\u4f1d\u5b50\u9818\u57df\u306b\u308f\u305f\u3063\u3066107\u306eMPB\u95a2\u9023\u907a\u4f1d\u7684\u5909\u7570\u304c\u540c\u5b9a\u3055\u308c\u3001\u305d\u306e\u3046\u306130\u306f\u65b0\u898f\u3067\u3057\u305f\u3002 \u307e\u3068\u3081\u308b\u3068\u3001\u3053\u308c\u3089\u306e\u5909\u7a2e\u306fMPB\u306e\u907a\u4f1d\u7387\u306e38\uff05\u3092\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002 \u767a\u898b\u3055\u308c\u305f\u5909\u7570\u4f53\u306e\u591a\u304f\u306f\u3001\u6bdb\u306e\u6210\u9577\u3068\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306b\u5bfe\u3059\u308b\u6bdb\u5305\u7d30\u80de\u306e\u5fdc\u7b54\u306b\u5f79\u5272\u3092\u679c\u305f\u3059\u907a\u4f1d\u5b50\u5185\u307e\u305f\u306f\u305d\u306e\u8fd1\u304f\u306b\u3042\u308a\u307e\u3059\u3002<br\/><\/p>\n\n<p><strong>\u77e5\u3063\u3066\u307e\u3059\u304b\uff1f<\/strong> \u4e00\u822c\u7684\u306a\u795e\u8a71\u306f\u3001\u3042\u306a\u305f\u304c\u7537\u6027\u306e\u5834\u5408\u3001MPB\u306f\u3042\u306a\u305f\u306e\u6bcd\u65b9\u306e\u7956\u7236\u306b\u307e\u3067\u3055\u304b\u306e\u307c\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u3002 \u305f\u3060\u3057\u3001\u3053\u308c\u306f\u5b8c\u5168\u306b\u6b63\u78ba\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002 MPB\u306b\u95a2\u9023\u3059\u308b1\u3064\u306e\u3088\u304f\u7279\u5fb4\u4ed8\u3051\u3089\u308c\u305f\u907a\u4f1d\u5b50\u306f\u3001\u6bdb\u5305\u7d30\u80de\u304c\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u691c\u51fa\u3059\u308b\u306e\u3092\u52a9\u3051\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306f\u9aea\u306e\u6210\u9577\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u3053\u306e\u907a\u4f1d\u5b50\u306fX\u67d3\u8272\u4f53\u4e0a\u306b\u3042\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u7537\u6027\u306e\u5834\u5408\u3001\u6bcd\u89aa\u304b\u3089\u53d7\u3051\u7d99\u304c\u308c\u3066\u3044\u307e\u3059\u3002 \u3057\u304b\u3057\u3001\u3053\u308c\u3092\u542b\u3080\u591a\u304f\u306e\u7814\u7a76\u306f\u3001MPB\u304c\u591a\u907a\u4f1d\u5b50\u6027\u969c\u5bb3\u3067\u3042\u308b\u3053\u3068\u3092\u5f37\u8abf\u3057\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001MBP\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u304c\u591a\u6570\u3042\u308a\u3001\u305d\u306e\u591a\u304f\u306f\u6027\u67d3\u8272\u4f53\u4e0a\u306b\u3042\u308a\u307e\u305b\u3093\u3002<a rel=\"noreferrer noopener\" href=\"https:\/\/en.wikipedia.org\/wiki\/Effects_of_long-term_contact_lens_wear_on_the_cornea\" target=\"_blank\"> [<\/a><a href=\"https:\/\/blog.helix.com\/male-pattern-baldness-genetics\/\">\u30bd\u30fc\u30b9]<\/a><\/p>\n\n<p><strong>\u30b5\u30f3\u30d7\u30eb\u7d50\u679c\uff1a<\/strong>\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/nebula-library-unlocking-genetic-research\/\">\u661f\u96f2\u7814\u7a76\u56f3\u66f8\u9928<\/a>\u3002 <\/p>\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\"><img decoding=\"async\" width=\"1024\" height=\"375\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/image-4-1024x375.png\" alt=\"MBP&#x30B5;&#x30F3;&#x30D7;&#x30EB;&#x7D50;&#x679C;\" class=\"wp-image-1129\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/image-4-1024x375.png 1024w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/image-4-300x110.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/image-4-768x281.png 768w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/image-4-1536x562.png 1536w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/image-4.png 924w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n<p><\/p>\n\n<p><strong>MBP\u95a2\u9023\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\uff1a<\/strong> rs4827528\u3001rs11087368\u3001rs71530654\u3001rs552649178\u3001rs12203592\u3001rs7542354\u3001rs77410716\u3001rs1422798\u3001rs939963\u3001rs11684254\u3001rs7061504\u3001rs34624408\u3001rs550618068\u3001rs4718886\u3001rs919462\u3001rs13021718\u3001rs7680591\u3001rs8085664\u3001rs11593840\u3001rs577845405\u3001rs17833789\u3001rs79593277\u3001rs113436165\u3001rs7642536\u3001rs2064251\u3001 rs11578119\u3001rs62433864\u3001rs7349332\u3001rs9803723\u3001rs11037975\u3001rs111668293\u3001rs68088846\u3001rs9692245\u3001rs16863765\u3001rs58788673\u3001rs9398803\u3001rs3781452\u3001rs11249243\u3001rs182973285\u3001rs7974900\u3001rs572756998\u3001rs2149150\u3001rs17265513\u3001rs534591951\u3001rs6788232\u3001rs12902958\u3001rs78448052\u3001rs534855217\u3001rs71421546\u3001rs530010717\u3001 rs77767830\u3001rs7976269\u3001rs12214131\u3001rs10930758\u3001rs5934505\u3001rs35892873\u3001rs10888690\u3001rs138773644\u3001rs16830188\u3001rs76972608\u3001rs191212334\u3001rs61784834\u3001rs62146540\u3001rs16877149\u3001rs79811440\u3001rs7164914\u3001rs12752809\u3001rs115182912\u3001rs10225279\u3001rs985546\u3001rs35255777\u3001rs76067940\u3001rs12144907\u3001rs9846246\u3001rs2876167\u3001 rs201089181\u3001rs59995943\u3001rs77177529\u3001rs73837363\u3001rs13405699\u3001rs200541723\u3001rs29073\u3001rs6752754\u3001rs10923528\u3001rs2256843 \u3001rs998245\u3001rs1704529\u3001rs72809171\u3001rs12509636\u3001rs551865390\u3001rs10843003\u3001rs2807691\u3001rs16827770\u3001rs12686549\u3001rs844193\u3001rs149801367\u3001rs335145\u3001rs10928235\u3001rs111931356\u3001rs7226979\u3001rs11714208\u3001rs<\/p>\n\n<p><strong>\u8ffd\u52a0\u306e\u30ea\u30bd\u30fc\u30b9\uff1a<\/strong><br\/><a href=\"https:\/\/ghr.nlm.nih.gov\/condition\/androgenetic-alopecia\">MPB<\/a><br\/><a href=\"https:\/\/www.youtube.com\/watch?v=N5plbx-i2Kw\">\u8131\u6bdb\u306e\u79d1\u5b66<\/a><br\/><\/p>\n\n<p><strong>\u6bce\u9031\u306e\u66f4\u65b0\uff1a<\/strong> 2020\u5e741\u670810\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u30bf\u30a4\u30c8\u30eb\uff1a\u7537\u6027\u578b\u8131\u6bdb\u75c7\u306eGWAS\u306f\u3001\u30ea\u30b9\u30af\u306e38\uff05\u3092\u8aac\u660e\u3059\u308b71\u306e\u611f\u53d7\u6027\u907a\u4f1d &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/ja\/%e9%81%ba%e4%bc%9d%e5%ad%a6-of-mpb-pirastu-2017\/\"> <span class=\"screen-reader-text\">\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08Pirastu\u30012017\u5e74\uff09<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5117,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4981],"tags":[],"class_list":["post-10351","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-4981"],"yoast_head":"<!-- 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