{"id":10705,"date":"2021-01-06T00:33:47","date_gmt":"2021-01-06T05:33:47","guid":{"rendered":"https:\/\/nebula.org\/blog\/is-%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84-2\/"},"modified":"2022-05-19T11:21:20","modified_gmt":"2022-05-19T15:21:20","slug":"is-%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84-2","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/ja\/is-%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84-2\/","title":{"rendered":"\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\uff08\u30ef\u30a4\u30c8\u30de\u30f3\u30012021\u5e74\uff09-\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u907a\u4f1d\u6027\u3067\u3059\u304b\uff1f"},"content":{"rendered":"\n<div class=\"wp-block-yoast-seo-table-of-contents yoast-table-of-contents\"><h2>\u76ee\u6b21<\/h2><ul><li><a href=\"#h-nebula-genomics-dna-report-for-alzheimer-s\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u661f\u96f2\u30b2\u30ce\u30df\u30af\u30b9DNA\u30ec\u30dd\u30fc\u30c8<\/a><\/li><li><a href=\"#h-what-is-alzheimer-s\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/a><\/li><li><a href=\"#h-is-alzheimer-s-genetic\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u907a\u4f1d\u6027\u3067\u3059\u304b\uff1f<\/a><\/li><li><a href=\"#h-current-research-on-genetic-alzheimer-s-updated-april-2021\" data-level=\"2\">\u907a\u4f1d\u7684\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u95a2\u3059\u308b\u73fe\u5728\u306e\u7814\u7a76 [Updated April 2021]<\/a><\/li><li><a href=\"#h-non-genetic-risk-factors\" data-level=\"2\">\u975e\u907a\u4f1d\u7684\u5371\u967a\u56e0\u5b50<\/a><\/li><li><a href=\"#h-epidemiology\" data-level=\"2\">\u75ab\u5b66<\/a><\/li><li><a href=\"#h-characteristics-and-symptoms-of-alzheimer-s\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u7279\u5fb4\u3068\u75c7\u72b6 <\/a><ul><li><a href=\"#h-early-stage-mild\" data-level=\"3\">\u521d\u671f\uff08\u8efd\u5ea6\uff09<\/a><\/li><li><a href=\"#h-middle-stage-moderate\" data-level=\"3\">\u4e2d\u671f\uff08\u4e2d\u7a0b\u5ea6\uff09<\/a><\/li><li><a href=\"#h-late-stage-severe\" data-level=\"3\">\u5f8c\u671f\uff08\u91cd\u5ea6\uff09<\/a><\/li><\/ul><\/li><li><a href=\"#h-diagnosis-of-alzheimer-s\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u8a3a\u65ad<\/a><\/li><li><a href=\"#h-treatment-of-alzheimer-s\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6cbb\u7642<\/a><\/li><li><a href=\"#h-prognosis-of-alzheimer-s\" data-level=\"2\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u4e88\u5f8c<\/a><\/li><\/ul><\/div>\n\n<h2 class=\"wp-block-heading\" id=\"h-nebula-genomics-dna-report-for-alzheimer-s\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u661f\u96f2\u30b2\u30ce\u30df\u30af\u30b9DNA\u30ec\u30dd\u30fc\u30c8<\/strong><\/h2>\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u907a\u4f1d\u7684\u3067\u3059\u304b\uff1f \u3053\u306e\u8cea\u554f\u306b\u7b54\u3048\u3088\u3046\u3068\u3057\u305f\u7814\u7a76\u306b\u57fa\u3065\u3044\u3066\u3001DNA\u30ec\u30dd\u30fc\u30c8\u3092\u4f5c\u6210\u3057\u307e\u3057\u305f\u3002 \u4ee5\u4e0b\u306b\u30b5\u30f3\u30d7\u30ebDNA\u30ec\u30dd\u30fc\u30c8\u3092\u793a\u3057\u307e\u3059\u3002 \u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u3055\u308c\u305fDNA\u30ec\u30dd\u30fc\u30c8\u3092\u5165\u624b\u3059\u308b\u306b\u306f\u3001<a href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\">\u5168\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b9<\/a>\uff01<\/p>\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"794\" height=\"699\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-report.png\" alt=\"&#x30A2;&#x30EB;&#x30C4;&#x30CF;&#x30A4;&#x30DE;&#x30FC;&#x75C5;&#x306F;&#x907A;&#x4F1D;&#x7684;&#x3067;&#x3059;&#x304B;&#xFF1F; NebulaGenomics&#x304B;&#x3089;&#x306E;&#x30B5;&#x30F3;&#x30D7;&#x30EB;&#x30EC;&#x30DD;&#x30FC;&#x30C8;&#x3002;\" class=\"wp-image-30490\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-report.png 794w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-report-300x264.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-report-768x676.png 768w\" sizes=\"(max-width: 794px) 100vw, 794px\" \/><\/figure><\/div>\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"791\" height=\"275\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-variants.png\" alt=\"&#x30A2;&#x30EB;&#x30C4;&#x30CF;&#x30A4;&#x30DE;&#x30FC;&#x75C5;&#x306F;&#x907A;&#x4F1D;&#x7684;&#x3067;&#x3059;&#x304B;&#xFF1F; NebulaGenomics&#x306E;&#x30B5;&#x30F3;&#x30D7;&#x30EB;&#x30D0;&#x30EA;&#x30A2;&#x30F3;&#x30C8;&#x5206;&#x6790;\" class=\"wp-image-30498\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-variants.png 791w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-variants-300x104.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2022\/05\/sample-alzheimers-variants-768x267.png 768w\" sizes=\"(max-width: 791px) 100vw, 791px\" \/><\/figure><\/div>\n\n<p>Nebula Genomics\u304c\u4e0a\u8a18\u306e\u8868\u306e\u907a\u4f1d\u7684\u5909\u7570\u3092\u5831\u544a\u3059\u308b\u65b9\u6cd5\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001 <a>NebulaResearchLibrary\u30c1\u30e5\u30fc\u30c8\u30ea\u30a2\u30eb<\/a>\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n<div class=\"wp-block-buttons aligncenter is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aligncenter\"><a class=\"wp-block-button__link has-vivid-cyan-blue-background-color has-background\" href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\"><strong>\u30b2\u30ce\u30e0\u306e\u914d\u5217\u3092\u6c7a\u5b9a\u3057\u3001200\u3092\u8d85\u3048\u308bDNA\u30ec\u30dd\u30fc\u30c8\u306b\u30a2\u30af\u30bb\u30b9\u3057\u3066\u304f\u3060\u3055\u3044\uff01<\/strong><\/a><\/div>\n<\/div>\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<figure class=\"wp-block-table aligncenter\"><table class=\"has-subtle-pale-pink-background-color has-background\"><tbody><tr><td><strong>\u3053\u306e\u60c5\u5831\u306f\u30012021\u5e744\u6708\u73fe\u5728\u306e\u6700\u8fd1\u306e\u79d1\u5b66\u7814\u7a76\u3092\u53cd\u6620\u3059\u308b\u3088\u3046\u306b\u66f4\u65b0\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-alzheimer-s\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/strong><\/h2>\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u795e\u7d4c\u5909\u6027\u75be\u60a3\u3067\u3042\u308a\u300165\u6b73\u4ee5\u4e0a\u306e\u4eba\u3005\u306b\u6700\u3082\u4e00\u822c\u7684\u306a\u5f62\u614b\u3067\u767a\u751f\u3057\u3001\u8a8d\u77e5\u75c7\u306e\u5897\u52a0\u3092\u7279\u5fb4\u3068\u3057\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n<p>\u305d\u308c\u3089\u306f\u3057\u3070\u3057\u3070\u4ea4\u63db\u53ef\u80fd\u306b\u4f7f\u7528\u3055\u308c\u307e\u3059\u304c\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u95a2\u9023\u3059\u308b\u8a8d\u77e5\u75c7\u306f\u7570\u306a\u308b\u72b6\u614b\u3092\u6307\u3057\u307e\u3059\u3002 \u8a8d\u77e5\u75c7\u306f\u3001\u8133\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3055\u307e\u3056\u307e\u306a\u75c5\u6c17\u306e\u7dcf\u79f0\u3067\u3042\u308a\u3001\u8a3a\u65ad\u57fa\u6e96\u306b\u57fa\u3065\u3044\u3066\u79d1\u5b66\u7684\u306a\u8b70\u8ad6\u3067\u660e\u78ba\u306b\u8aac\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u8a8d\u77e5\u6a5f\u80fd\u3001\u611f\u60c5\u7684\u304a\u3088\u3073\u793e\u4f1a\u7684\u80fd\u529b\u306e\u55aa\u5931\u306e\u5897\u52a0\u306f\u3001\u3059\u3079\u3066\u306e\u30bf\u30a4\u30d7\u306e\u8a8d\u77e5\u75c7\u306b\u5171\u901a\u3057\u3066\u3044\u307e\u3059\u3002 \u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u8a8d\u77e5\u75c7\u306e\u6700\u3082\u4e00\u822c\u7684\u306a\u5f62\u614b\u3067\u3042\u308a\u3001\u75c7\u4f8b\u306e<a href=\"https:\/\/www.alz.org\/alzheimers-dementia\/what-is-alzheimers\">60\u301c80\uff05<\/a>\u3092\u5360\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<p>\u3053\u306e\u75c5\u6c17\u306f\u9032\u884c\u6027\u3067\u3001\u8a8d\u77e5\u75c7\u306e\u75c7\u72b6\u306f\u6642\u9593\u3068\u3068\u3082\u306b\u5f90\u3005\u306b\u60aa\u5316\u3057\u307e\u3059\u3002 2017\u5e74\u306e\u6642\u70b9\u3067\u3001<a href=\"https:\/\/www.cdc.gov\/media\/releases\/2017\/p0525-alzheimer-deaths.html\"> 6\u756a\u76ee\u306b\u591a\u3044\u6b7b\u56e0<\/a>\u7c73\u56fd\u3067\u306f\u3002 <\/p>\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"624\" height=\"293\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/alzheimers-and-memory.jpg\" alt=\"&#x8A18;&#x61B6;&#x55AA;&#x5931;&#x306E;&#x5199;&#x771F;&#x306E;&#x8AAC;&#x660E;\" class=\"wp-image-19677\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/alzheimers-and-memory.jpg 624w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/alzheimers-and-memory-300x141.jpg 300w\" sizes=\"(max-width: 624px) 100vw, 624px\" \/><figcaption>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u3001\u8a18\u61b6\u3068\u8a8d\u77e5\u306e\u30d7\u30ed\u30bb\u30b9\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002<a href=\"https:\/\/pixabay.com\/photos\/alzheimer-s-dementia-man-wheelchair-3034960\/\"> Pinterest.com<\/a> \u3002<\/figcaption><\/figure><\/div>\n\n<h2 class=\"wp-block-heading\" id=\"h-is-alzheimer-s-genetic\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u907a\u4f1d\u6027\u3067\u3059\u304b\uff1f<\/strong><\/h2>\n\n<p>\u73fe\u5728\u307e\u3067\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e8%aa%8d%e7%9f%a5%e7%97%87-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e<\/a>\u539f\u56e0\u306f\u5b8c\u5168\u306b\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u8981\u56e0\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u7591\u308f\u308c\u3066\u3044\u307e\u3059\u3002 \u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6700\u5927\u306e\u5371\u967a\u56e0\u5b50\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n\n<ul class=\"wp-block-list\"><li>\u9ad8\u9f62\u8005\u306e\u9ad8\u9f62\u8005<\/li><li>APOE\u907a\u4f1d\u5b50\u306ee4\u578b\u3092\u904b\u3076<\/li><li>\u5bb6\u65cf\u306e\u6b74\u53f2<\/li><\/ul>\n\n<p>\u907a\u4f1d\u5b66\u3092\u7406\u89e3\u3059\u308b\uff1a\u907a\u4f1d\u7684\u306b\u3001ApoE\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u4f53\u306f\u75c5\u6c17\u306e\u767a\u75c7\u306e\u5371\u967a\u56e0\u5b50\u3068\u3057\u3066\u7279\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u3055\u3089\u306b\u3001\u30d7\u30ec\u30bb\u30cb\u30ea\u30f3-1\u304a\u3088\u3073-2\u3068\u547c\u3070\u308c\u308b3\u3064\u306e\u7570\u306a\u308b\u30ea\u30b9\u30af\u907a\u4f1d\u5b50\u3068\u30a2\u30df\u30ed\u30a4\u30c9\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u8cea\uff08APP\uff09\u306e\u539f\u56e0\u3068\u306a\u308b\u5909\u7570\u3002 \u3053\u308c\u3089\u306e\u7a81\u7136\u5909\u7570\u306f\u3001\u75c7\u4f8b\u306e\u3054\u304f\u4e00\u90e8\uff081\uff05\u4ee5\u4e0b\uff09\u3092\u5f15\u304d\u8d77\u3053\u3059\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u305f\u3060\u3057\u3001APP\u907a\u4f1d\u5b50\u307e\u305f\u306f\u30d7\u30ec\u30bb\u30cb\u30ea\u30f31\u907a\u4f1d\u5b50\u3078\u306e\u5909\u7570\u3092\u53d7\u3051\u7d99\u3050\u60a3\u8005\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u767a\u75c7\u3059\u308b\u3053\u3068\u304c\u4fdd\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30d7\u30ec\u30bb\u30cb\u30ea\u30f32\u907a\u4f1d\u5b50\u3078\u306e\u5909\u7570\u3092\u53d7\u3051\u7d99\u3050\u60a3\u8005\u306f95\uff05\u306e\u78ba\u7387\u3067\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n<p>\u30c0\u30a6\u30f3\u75c7\u306e\u4eba\u3092\u7279\u5fb4\u4ed8\u3051\u308b\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u306821\u756a\u67d3\u8272\u4f53\u306e\u4f59\u5206\u306a\u30b3\u30d4\u30fc\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u306b\u5f37\u304f\u5f71\u97ff\u3059\u308b\u307e\u308c\u306a\u907a\u4f1d\u7684\u8981\u56e0\u3067\u3059\u3002 <\/p>\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e<\/a>\u7d20\u56e0\u3092\u8a3c\u660e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u907a\u4f1d\u5b50\u691c\u67fb\u306b\u8208\u5473\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u3053\u306e\u88fd\u54c1\u30ec\u30d3\u30e5\u30fc\u3092\u30c1\u30a7\u30c3\u30af\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\uff1a<\/p>\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/nebula.org\/blog\/23andme-review\/\">23andMe<\/a> -\u5065\u5eb7+\u7956\u5148\u30b5\u30fc\u30d3\u30b9<\/li><li><a href=\"https:\/\/nebula.org\/blog\/ja\/genedx-%e3%83%ac%e3%83%93%e3%83%a5%e3%83%bc\/\">GeneDx<\/a> -\u591a\u7a2e\u591a\u69d8\u306a\u81e8\u5e8a\u30b2\u30ce\u30e0\u691c\u67fb<\/li><li><a href=\"https:\/\/nebula.org\/blog\/ja\/invitae-%e3%83%ac%e3%83%93%e3%83%a5%e3%83%bc\/\">Invitae<\/a> -\u8a3a\u65ad\u3001\u4e88\u9632\u7684\u5065\u5eb7\u3001\u30ea\u30d7\u30ed\u30c0\u30af\u30c6\u30a3\u30d6\u30d8\u30eb\u30b9<\/li><li><a href=\"https:\/\/nebula.org\/blog\/ja\/%e7%84%a1%e6%95%b0%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e3%83%ac%e3%83%93%e3%83%a5%e3%83%bc\/\">\u7121\u6570\u306e\u907a\u4f1d\u5b66<\/a>-\u8a3a\u65ad\u3001\u751f\u6b96\u691c\u67fb\u3001\u7cbe\u5bc6\u533b\u7642\u691c\u67fb<\/li><\/ul>\n\n<h2 class=\"wp-block-heading\" id=\"h-current-research-on-genetic-alzheimer-s-updated-april-2021\"><strong>\u907a\u4f1d\u7684\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u95a2\u3059\u308b\u73fe\u5728\u306e\u7814\u7a76 [Updated April 2021]<\/strong><\/h2>\n\n<p>\u30a2\u30d5\u30ea\u30ab\u7cfb\u30a2\u30e1\u30ea\u30ab\u4eba\u306f\u3001\u540c\u3058\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306e\u975e\u30d2\u30b9\u30d1\u30cb\u30c3\u30af\u7cfb\u767d\u4eba\u306e\u5bfe\u5fdc\u8005\u3088\u308a\u30822\u500d\u75c5\u6c17\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 2020\u5e7412\u6708\u3001 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7815481\/\">AIMS Neuroscience\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u95a2\u4fc2\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u907a\u4f1d\u5b50\u8981\u7d20\u3068\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u306b\u95a2\u3059\u308b\u8a18\u4e8b\u3092\u767a\u8868<\/a>\u3057\u307e\u3057\u305f\u3002<\/p>\n\n<p>\u7d50\u679c\u306f\u3001\u95a2\u4e0e\u3059\u308b\u4e3b\u8981\u306a\u751f\u7269\u5b66\u7684\u7d4c\u8def\u3068\u3001\u3053\u308c\u3089\u306e\u7d4c\u8def\u306e\u305d\u308c\u305e\u308c\u304c\u75c5\u6c17\u306e\u767a\u75c7\u306b\u5f79\u7acb\u3063\u305f\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<p>2021\u5e743\u6708\u3001<a href=\"https:\/\/www.nature.com\/articles\/s41598-021-86822-x\">\u4e2d\u6751\u7fa9\u82f1\u304c\u7387\u3044\u308b\u79d1\u5b66\u8005\u306f\u3001\u30ea\u30a2\u30ce\u30b8\u30f3\u53d7\u5bb9\u4f53\u3078\u306e\u30ab\u30eb\u30e2\u30b8\u30e5\u30ea\u30f3\u7d50\u5408\u306e\u5f37\u5316\u304c\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u95a2\u9023\u3059\u308b\u795e\u7d4c\u7d30\u80de\u306e\u55aa\u5931\u3092\u5236\u9650\u3059\u308b\u306e\u306b\u3069\u306e\u3088\u3046\u306b\u5f79\u7acb\u3064\u304b\u306b\u3064\u3044\u3066\u306e\u8a18\u4e8b\u3092\u767a\u8868\u3057<\/a>\u307e\u3057\u305f\u3002 \u3053\u306e\u5b9f\u9a13\u306e\u76ee\u7684\u306f\u3001\u72b6\u614b\u3092\u6cbb\u7642\u3059\u308b\u65b0\u3057\u3044\u65b9\u6cd5\u3092\u898b\u3064\u3051\u308b\u306e\u3092\u52a9\u3051\u308b\u3053\u3068\u3067\u3057\u305f\u3002<\/p>\n\n<p>\u30e9\u30f3\u30c0\u30e0\u5316\u81e8\u5e8a\u8a66\u9a13\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3088\u308b\u3068\u3001\u9ad8\u8840\u5727\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u8a8d\u77e5\u969c\u5bb3\u3084\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 <a href=\"https:\/\/jamanetwork.com\/journals\/jamaneurology\/article-abstract\/2776960\">JAMA\u795e\u7d4c\u5b66\u306f\u3001\u300c\u96c6\u4e2d\u7684\u8840\u5727\u5236\u5fa1\u3068\u6a19\u6e96\u8840\u5727\u5236\u5fa1\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u78c1\u6c17\u5171\u9cf4\u753b\u50cf\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u306e\u95a2\u9023\uff1aSPRINTMIND\u7121\u4f5c\u70ba\u5316\u8a66\u9a13\u306e\u4e8c\u6b21\u5206\u6790\u300d\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u306e\u5225\u306e\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u3066<\/a>\u3044\u307e\u3059\u3002 \u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u5bfe\u3059\u308b<a href=\"https:\/\/nebula.org\/blog\/ja\/%e8%a1%80%e5%9c%a7%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e3%82%a6%e3%82%a9%e3%83%bc%e3%83%ac%e3%83%b3-2019\/\">\u9ad8\u8840\u5727<\/a>\u307e\u305f\u306f\u9ad8\u8840\u5727\u306e\u7ba1\u7406\u306e\u52b9\u679c\u3092\u8abf\u3079\u307e\u3059\u3002 <\/p>\n\n<p>\u3053\u306e\u7814\u7a76\u306b\u306f\u3001\u96c6\u4e2d\u6cbb\u7642\u3068\u8ffd\u8de1\u78c1\u6c17\u5171\u9cf4\u3092\u53d7\u3051\u305f\u9ad8\u8840\u5727\u75c7\u306e\u6210\u4eba454\u4eba\u304c\u53c2\u52a0\u3057\u3066\u3044\u307e\u3059\u3002 \u7d50\u679c\u306f\u3001\u60a3\u8005\u3092\u96c6\u4e2d\u7684\u307e\u305f\u306f\u6a19\u6e96\u7684\u306a\u8840\u5727\u6cbb\u7642\u306b\u304b\u3051\u308b\u3053\u3068\u306f\u3001\u5f7c\u3089\u306e\u78c1\u6c17\u5171\u9cf4\u753b\u50cf\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306b\u81e8\u5e8a\u7684\u306b\u6709\u610f\u306a\u9055\u3044\u304c\u306a\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002 \u3057\u305f\u304c\u3063\u3066\u3001\u9ad8\u8840\u5727\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3068\u306f\u89e3\u91c8\u3055\u308c\u307e\u305b\u3093\u3002 <\/p>\n\n<h2 class=\"wp-block-heading\" id=\"h-non-genetic-risk-factors\"><strong>\u975e\u907a\u4f1d\u7684\u5371\u967a\u56e0\u5b50<\/strong><\/h2>\n\n<p>\u8001\u5316\u3068\u907a\u4f1d\u7684\u7d20\u56e0\u306b\u52a0\u3048\u3066\u3001\u4ed6\u306e\u5065\u5eb7\u3068\u74b0\u5883\u8981\u56e0\u304c\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002<\/p>\n\n<ul class=\"wp-block-list\"><li>\u4ee5\u524d\u306e\u982d\u84cb\u8133\u5916\u50b7<\/li><li>\u4ee3\u8b1d\u6027\u75be\u60a3 <\/li><li>\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3068\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7<\/li><li>\u7cd6\u5c3f\u75c5 <\/li><li>\u9ad8<a href=\"https:\/\/nebula.org\/blog\/ja\/%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%83%ac%e3%83%99%e3%83%ab%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-kathiresan-2008\/\">\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024<\/a> <\/li><li>\u5fc3\u81d3\u75c5\u306e\u3088\u3046\u306a<a href=\"https:\/\/nebula.org\/blog\/ja\/%e5%86%a0%e7%8a%b6%e5%8b%95%e8%84%88%e7%96%be%e6%82%a3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e5%b0%8f%e5%b1%b1-2020\/\">\u5fc3\u81d3\u8840\u7ba1\u7cfb\u306e\u75c5\u6c17<\/a><\/li><li>\u9ad8\u8840\u5727<\/li><li><a href=\"https:\/\/nebula.org\/blog\/ja\/%e8%84%b3%e5%8d%92%e4%b8%ad%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-malik-2018\/\">\u8133\u5352\u4e2d<\/a><\/li><\/ul>\n\n<p>\u5065\u5eb7\u72b6\u614b\u304c\u826f\u597d\u3067\u8eab\u4f53\u6d3b\u52d5\u306b\u5f93\u4e8b\u3057\u3066\u3044\u308b\u4eba\u306f\u3001\u75c7\u72b6\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u304c\u4f4e\u304f\u306a\u308a\u307e\u3059\u3002 <\/p>\n\n<p>\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff08MCI\uff09\u306f\u3001\u60a3\u8005\u304c\u8a18\u61b6\u529b\u3084\u601d\u8003\u529b\u306a\u3069\u306e\u8a8d\u77e5\u80fd\u529b\u306e\u308f\u305a\u304b\u3067\u306f\u3042\u308b\u304c\u9855\u8457\u306a\u4f4e\u4e0b\u3092\u7d4c\u9a13\u3059\u308b\u5225\u306e\u75be\u60a3\u3067\u3059\u3002 MCI\u306e\u4eba\u306f\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n<h2 class=\"wp-block-heading\" id=\"h-epidemiology\"><strong>\u75ab\u5b66<\/strong><\/h2>\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u5354\u4f1a\u306b\u3088\u308b\u3068\u30012019\u5e74\u306b\u7c73\u56fd\u3067\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u60a3\u3063\u3066\u3044\u308b\u4eba\u306f\u7d04580\u4e07\u4eba\u3067\u3001\u305d\u306e97\uff05\u304c65\u6b73\u4ee5\u4e0a\u3067\u3059\u3002 \u3053\u306e\u6570\u306f\u81e8\u5e8a\u8a3a\u65ad\u57fa\u6e96\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u75c5\u6c17\u306f\u3001\u8a18\u61b6\u3068\u8a8d\u77e5\u3092\u5236\u5fa1\u3059\u308b\u8133\u306e\u751f\u7269\u5b66\u7684\u5909\u5316\u3092\u901a\u3058\u3066\u3001\u75c7\u72b6\u304c\u73fe\u308c\u308b\u4f55\u5e74\u3082\u524d\u306b\u59cb\u307e\u308b\u3053\u3068\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<p>\u5973\u6027\u306f\u7537\u6027\u3088\u308a\u3082\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u304c\u975e\u5e38\u306b\u9ad8\u3044\u3067\u3059\u3002 \u7406\u7531\u306e1\u3064\u306f\u3001\u5e73\u5747\u4f59\u547d\u304c\u9577\u3044\u3053\u3068\u3067\u3059\u3002 \u3055\u3089\u306b\u3001\u6700\u8fd1\u306e<a href=\"https:\/\/www.smh.com.au\/lifestyle\/health-and-wellness\/a-possible-link-between-menopause-and-alzheimer-s-is-scaring-women-including-me-20190605-p51usp.html\">\u7814\u7a76<\/a>\u3067\u306f\u3001\u9589\u7d4c\u4e2d\u306e\u30db\u30eb\u30e2\u30f3\u30ec\u30d9\u30eb\u306e\u5909\u52d5\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u3068\u306e\u95a2\u4fc2\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002 \u767d\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u30de\u30a4\u30ce\u30ea\u30c6\u30a3\u306e\u6709\u75c5\u7387\u3082\u9ad8\u3044\u3067\u3059\u3002 \u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3084\u305d\u306e\u4ed6\u306e\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u306e\u5897\u52a0\u306b\u95a2\u9023\u3059\u308b\u5fc3\u8840\u7ba1\u75be\u60a3\u3084\u7cd6\u5c3f\u75c5\u306a\u3069\u306e\u5065\u5eb7\u72b6\u614b\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u3001\u3053\u308c\u3089\u306e\u9055\u3044\u3092\u8aac\u660e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<p>2017\u5e74\u306b\u306f\u300130\u301c64\u6b73\u306e37,000\u4eba\u306e\u5546\u696d\u4fdd\u967a\u306b\u52a0\u5165\u3057\u3066\u3044\u308b\u30a2\u30e1\u30ea\u30ab\u4eba\u304c<a href=\"https:\/\/www.bcbs.com\/the-health-of-america\/reports\/early-onset-dementia-alzheimers-disease-affecting-younger-american-adults#:~:text=In%202017%2C%2037%2C000%20commercially%20insured,2013%20to%203.0%20in%202017.\">\u65e9\u671f\u767a\u75c7<\/a>\u4e88\u60f3\u3088\u308a\u3082\u82e5\u3044\u5e74\u9f62\u306e\u4eba\u306b\u767a\u751f\u3059\u308b\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3002 <\/p>\n\n<p><a href=\"https:\/\/www.alzint.org\/resource\/world-alzheimer-report-2015\/\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u30a4\u30f3\u30bf\u30fc\u30ca\u30b7\u30e7\u30ca\u30eb\u306e<\/a>\u63a8\u5b9a\u306b\u3088\u308b\u3068\u30012015\u5e74\u306b\u306f\u4e16\u754c\u4e2d\u3067\u7d044,680\u4e07\u4eba\u304c\u8a8d\u77e5\u75c7\u306e\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3057\u305f\u3002 \u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30e2\u30c7\u30eb\u306e\u8a55\u4fa1\u306b\u3088\u308b\u3068\u3001\u56fd\u9023\u306b\u3088\u308b\u4eba\u53e3\u4e88\u6e2c\u306b\u57fa\u3065\u304f\u3053\u306e\u6570\u306f\u30012050\u5e74\u307e\u3067\u306b\u7d041\u51043150\u4e07\u4eba\u306e\u60a3\u8005\u306b\u5897\u52a0\u3059\u308b\u3068\u4e88\u60f3\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<h2 class=\"wp-block-heading\" id=\"h-characteristics-and-symptoms-of-alzheimer-s\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u7279\u5fb4\u3068\u75c7\u72b6<\/strong> <\/h2>\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u3001\u901a\u5e38\u3001\u65e5\u5e38\u751f\u6d3b\u306e\u6d3b\u52d5\u306b\u5bfe\u51e6\u3059\u308b\u80fd\u529b\u306e\u4f4e\u4e0b\u3092\u4f34\u3046\u8a8d\u77e5\u80fd\u529b\u306e\u4f4e\u4e0b\u306e\u5897\u52a0\u3001\u884c\u52d5\u7570\u5e38\u306e\u5897\u52a0\u304a\u3088\u3073\u795e\u7d4c\u7cbe\u795e\u75c7\u72b6\u306e\u5897\u52a0\u3092\u7279\u5fb4\u3068\u3057\u307e\u3059\u3002 \u8a18\u61b6\u55aa\u5931\u306a\u3069\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u75c7\u72b6\u306f\u3001\u75c5\u6c17\u306e\u521d\u671f\u306b\u306f\u8efd\u5ea6\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u5f8c\u671f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3067\u306f\u3057\u3070\u3057\u3070\u3088\u308a\u9855\u8457\u306b\u306a\u308a\u3001\u500b\u4eba\u306f\u4f1a\u8a71\u3092\u7d9a\u3051\u3066\u74b0\u5883\u306b\u53cd\u5fdc\u3059\u308b\u80fd\u529b\u3092\u5931\u3044\u307e\u3059\u3002 <\/p>\n\n<p>\u6700\u521d\u306e\u81e8\u5e8a\u75c7\u72b6\u304c\u73fe\u308c\u308b\u4f55\u5e74\u3082\u524d\u306b\u3001\u8aa4\u3063\u3066\u6298\u308a\u305f\u305f\u307e\u308c\u305f\u30d9\u30fc\u30bf\u30a2\u30df\u30ed\u30a4\u30c9\uff08A\u03b2\uff09\u30da\u30d7\u30c1\u30c9\u304b\u3089\u306a\u308b\u30d7\u30e9\u30fc\u30af\u3068\u3082\u3064\u308c\u304c\u8133\u306e\u4e00\u90e8\u306b\u5f62\u6210\u3055\u308c\u307e\u3059\u3002 \u30dc\u30fc\u30eb\u306e\u5f62\u3067\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u6c88\u7740\u3059\u308b\u30a2\u30df\u30ed\u30a4\u30c9\u6591\u3068\u30cb\u30e5\u30fc\u30ed\u30d5\u30a3\u30d6\u30ea\u30eb\u306f\u3001\u3053\u306e\u75c5\u6c17\u306e\u7279\u5fb4\u3067\u3059\u3002 \u3053\u306e\u795e\u7d4c\u5909\u6027\u75be\u60a3\u3067\u306f\u3001\u6b20\u9665\u306e\u3042\u308b\u30bf\u30a6\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u30cb\u30e5\u30fc\u30ed\u30f3\uff08\u8133\u7d30\u80de\uff09\u4f53\u304b\u3089\u30cb\u30e5\u30fc\u30ed\u30f3\u8ef8\u306b\u4ed8\u7740\u3057\u3001\u7d30\u80de\u3092\u7121\u529b\u5316\u3059\u308b\u305f\u3081\u3001\u3053\u306e\u75be\u60a3\u306f\u30bf\u30a6\u30aa\u30d1\u30c1\u30fc\u306b\u5c5e\u3057\u307e\u3059\u3002 \u75c5\u6c17\u304c\u9032\u884c\u3059\u308b\u3068\u3001\u8133\u7d30\u80de\u304c\u6b7b\u306b\u3001\u7d30\u80de\u9593\u306e\u3064\u306a\u304c\u308a\u304c\u5931\u308f\u308c\u3001\u8a8d\u77e5\u969c\u5bb3\u304c\u60aa\u5316\u3057\u307e\u3059\u3002<\/p>\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"624\" height=\"483\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/The-effects-of-Alzheimers-on-neurons.png\" alt=\"&#x30A2;&#x30EB;&#x30C4;&#x30CF;&#x30A4;&#x30DE;&#x30FC;&#x75C5;&#x306E;&#x30CB;&#x30E5;&#x30FC;&#x30ED;&#x30F3;&#x75BE;&#x60A3; \" class=\"wp-image-19685\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/The-effects-of-Alzheimers-on-neurons.png 624w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/The-effects-of-Alzheimers-on-neurons-300x232.png 300w\" sizes=\"(max-width: 624px) 100vw, 624px\" \/><figcaption>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u795e\u7d4c\u75c5\u7406\u5b66\u306e\u30a4\u30e9\u30b9\u30c8\u3002 \u30d6\u30eb\u30fc\u30b9\u30d6\u30e9\u30a6\u30b9\u3002<a href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/deed.en\">\u5e30\u5c5e-\u7d99\u627f4.0\u30a4\u30f3\u30bf\u30fc\u30ca\u30b7\u30e7\u30ca\u30eb<\/a>\u3002<\/figcaption><\/figure><\/div>\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u8001\u5316\u306e\u6b63\u5e38\u306a\u90e8\u5206\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002 \u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6700\u521d\u306e\u75c7\u72b6\u306f\u3001\u5f71\u97ff\u3092\u53d7\u3051\u308b\u4eba\u3005\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002 \u8a18\u61b6\u306e\u554f\u984c\u306f\u901a\u5e38\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6700\u521d\u306e\u9855\u8457\u306a\u5146\u5019\u306e1\u3064\u3067\u3059\u3002 \u8efd\u5ea6\u306e\u8a8d\u77e5\u969c\u5bb3\u3082\u521d\u671f\u75c7\u72b6\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u75c5\u6c17\u304c\u9032\u884c\u3059\u308b\u306b\u3064\u308c\u3066\u3001\u4eba\u3005\u306f\u3088\u308a\u5927\u304d\u306a\u8a18\u61b6\u55aa\u5931\u3068\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3092\u7d4c\u9a13\u3057\u307e\u3059\u3002 <\/p>\n\n<p>\u56fd\u7acb\u885b\u751f\u7814\u7a76\u6240\u306e\u56fd\u7acb\u30bb\u30f3\u30bf\u30fc\u3067\u3042\u308b\u56fd\u7acb<a href=\"https:\/\/www.nia.nih.gov\/health\/what-are-signs-alzheimers-disease\">\u8001\u5316\u7814\u7a76\u6240\u306b<\/a>\u3088\u308b\u3068\u3001\u4eba\u3005\u306f\u3055\u307e\u3056\u307e\u306a\u6bb5\u968e\u3067\u3044\u304f\u3064\u304b\u306e\u75c7\u72b6\u3092\u7d4c\u9a13\u3057\u307e\u3059\uff1a\u8efd\u5ea6\uff08\u521d\u671f\uff09\u3001\u4e2d\u7b49\u5ea6\uff08\u4e2d\u671f\uff09\u3001\u304a\u3088\u3073\u91cd\u5ea6\uff08\u5f8c\u671f\uff09\u3002<\/p>\n\n<h3 class=\"wp-block-heading\" id=\"h-early-stage-mild\">\u521d\u671f\uff08\u8efd\u5ea6\uff09<\/h3>\n\n<p>\u60a3\u8005\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u521d\u671f\u6bb5\u968e\u3067\u72ec\u7acb\u3057\u3066\u6a5f\u80fd\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u30aa\u30d6\u30b8\u30a7\u30af\u30c8\u3092\u7f6e\u304d\u5fd8\u308c\u305f\u308a\u3001\u306a\u3058\u307f\u306e\u3042\u308b\u8a00\u8449\u3092\u5fd8\u308c\u305f\u308a\u3059\u308b\u306a\u3069\u3001\u8a18\u61b6\u304c\u5931\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002 \u75c7\u72b6\u306f\u5e83\u304f\u306f\u660e\u3089\u304b\u3067\u306f\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u89aa\u3057\u3044\u5bb6\u65cf\u3084\u53cb\u4eba\u304c\u6c17\u4ed8\u304f\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002 <\/p>\n\n<ul class=\"wp-block-list\"><li>\u8a18\u61b6\u55aa\u5931<\/li><li>\u60aa\u3044\u6c7a\u5b9a\u306b\u3064\u306a\u304c\u308b\u60aa\u3044\u5224\u65ad<\/li><li>\u81ea\u767a\u6027\u3068\u30a4\u30cb\u30b7\u30a2\u30c1\u30d6\u306e\u611f\u899a\u306e\u55aa\u5931<\/li><li>\u901a\u5e38\u306e\u65e5\u5e38\u696d\u52d9\u3092\u5b8c\u4e86\u3059\u308b\u306e\u306b\u6642\u9593\u304c\u304b\u304b\u308b<\/li><li>\u7e70\u308a\u8fd4\u3057\u8cea\u554f<\/li><li>\u304a\u91d1\u306e\u53d6\u308a\u6271\u3044\u3068\u8acb\u6c42\u66f8\u306e\u652f\u6255\u3044\u306e\u554f\u984c<\/li><li>\u3055\u307e\u3088\u3063\u3066\u8ff7\u5b50\u306b\u306a\u308b<\/li><li>\u7269\u3092\u7d1b\u5931\u3057\u305f\u308a\u3001\u5947\u5999\u306a\u5834\u6240\u306b\u7f6e\u304d\u5fd8\u308c\u305f\u308a\u3059\u308b<\/li><li>\u6c17\u5206\u3068<a href=\"https:\/\/nebula.org\/blog\/ja\/%e3%83%91%e3%83%bc%e3%82%bd%e3%83%8a%e3%83%aa%e3%83%86%e3%82%a3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-lo-2017\/\">\u6027\u683c<\/a>\u306e\u5909\u5316<\/li><li>\u4e0d\u5b89\u304a\u3088\u3073\/\u307e\u305f\u306f\u653b\u6483\u6027\u306e\u5897\u52a0<\/li><\/ul>\n\n<h3 class=\"wp-block-heading\" id=\"h-middle-stage-moderate\">\u4e2d\u671f\uff08\u4e2d\u7a0b\u5ea6\uff09<\/h3>\n\n<p>\u3053\u306e\u30bf\u30a4\u30d7\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u4f55\u5e74\u3082\u7d9a\u304f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u8a8d\u77e5\u75c7\u306e\u75c7\u72b6\u306f\u3088\u308a\u9855\u8457\u3067\u3042\u308a\u3001\u305d\u306e\u4eba\u306f\u6df7\u4e71\u3057\u305f\u308a\u3001\u30a4\u30e9\u30a4\u30e9\u3057\u305f\u308a\u3001\u6012\u3063\u305f\u308a\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002 <\/p>\n\n<ul class=\"wp-block-list\"><li>\u8a18\u61b6\u55aa\u5931\u3068\u6df7\u4e71\u306e\u5897\u52a0<\/li><li>\u65b0\u3057\u3044\u3053\u3068\u3092\u5b66\u3076\u3053\u3068\u304c\u3067\u304d\u306a\u3044<\/li><li>\u8a00\u8a9e\u306e\u96e3\u3057\u3055\u3068\u6570\u5b57\u306e\u8aad\u307f\u53d6\u308a\u3001\u66f8\u304d\u8fbc\u307f\u3001\u64cd\u4f5c\u306e\u554f\u984c<\/li><li>\u601d\u8003\u3092\u6574\u7406\u3057\u3001\u8ad6\u7406\u7684\u306b\u8003\u3048\u308b\u3053\u3068\u306e\u96e3\u3057\u3055<\/li><li>\u6ce8\u610f\u529b\u306e\u77ed\u7e2e<\/li><li>\u65b0\u3057\u3044\u72b6\u6cc1\u306b\u5bfe\u51e6\u3059\u308b\u969b\u306e\u554f\u984c<\/li><li>\u670d\u3092\u7740\u308b\u306a\u3069\u306e\u591a\u6bb5\u968e\u306e\u30bf\u30b9\u30af\u3092\u5b9f\u884c\u3059\u308b\u3053\u3068\u306e\u96e3\u3057\u3055<\/li><li>\u5bb6\u65cf\u3084\u53cb\u4eba\u306e\u8a8d\u8b58\u306e\u554f\u984c<\/li><li>\u5e7b\u899a\u3001\u5984\u60f3\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e7%b2%be%e7%a5%9e%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84-2\/\">\u5984\u60f3<\/a><\/li><li>\u4e0d\u9069\u5207\u306a\u6642\u9593\u3084\u5834\u6240\u3067\u306e\u8131\u8863\u3084\u4e0b\u54c1\u306a\u8a00\u8449\u9063\u3044\u306a\u3069\u306e\u885d\u52d5\u7684\u306a\u884c\u52d5<\/li><li>\u6012\u308a\u306e\u4e0d\u9069\u5207\u306a\u7206\u767a<\/li><li>\u843d\u3061\u7740\u304d\u306e\u306a\u3055\u3001\u4e0d\u5b89\u3001\u8208\u596e\u3001\u6d99\u3001\u3068\u308a\u3068\u3081\u306e\u306a\u3044\u3053\u3068-\u7279\u306b\u5348\u5f8c\u9045\u304f\u307e\u305f\u306f\u5915\u65b9\u306b<\/li><li>\u7e70\u308a\u8fd4\u3057\u306e\u767a\u8a00\u3084\u52d5\u304d\u3001\u30e9\u30f3\u30c0\u30e0\u306a\u7b4b\u8089\u306e\u3051\u3044\u308c\u3093<\/li><\/ul>\n\n<h3 class=\"wp-block-heading\" id=\"h-late-stage-severe\">\u5f8c\u671f\uff08\u91cd\u5ea6\uff09<\/h3>\n\n<p>\u500b\u4eba\u306f\u3001\u81ea\u5206\u306e\u74b0\u5883\u306b\u5bfe\u5fdc\u3057\u3001\u4f1a\u8a71\u3092\u884c\u3044\u3001\u6700\u7d42\u7684\u306b\u306f\u52d5\u304d\u3092\u5236\u5fa1\u3059\u308b\u80fd\u529b\u3092\u5931\u3044\u307e\u3059\u3002 \u500b\u4eba\u306f\u901a\u5e38\u3001\u65e5\u5e38\u306e\u6d3b\u52d5\u306e\u4f1d\u9054\u3068\u5b9f\u884c\u304c\u56f0\u96e3\u3067\u3059\u3002 <\/p>\n\n<ul class=\"wp-block-list\"><li>\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u304c\u53d6\u308c\u306a\u3044<\/li><li>\u6e1b\u91cf<\/li><li><a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e3%81%a6%e3%82%93%e3%81%8b%e3%82%93-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u767a\u4f5c<\/a><\/li><li>\u76ae\u819a\u611f\u67d3\u75c7<\/li><li>\u56a5\u4e0b\u56f0\u96e3<\/li><li>\u3046\u3081\u304d\u58f0\u3001\u3046\u3081\u304d\u58f0\u3001\u307e\u305f\u306f\u3046\u3081\u304d\u58f0<\/li><li>\u7761\u7720\u306e\u5897\u52a0<\/li><li>\u6392\u4fbf\u3068\u8180\u80f1\u306e\u5236\u5fa1\u306e\u55aa\u5931<\/li><\/ul>\n\n<h2 class=\"wp-block-heading\" id=\"h-diagnosis-of-alzheimer-s\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u8a3a\u65ad<\/strong><\/h2>\n\n<p>\u3053\u306e\u72b6\u614b\u306f\u3001\u75c5\u6c17\u306e\u8efd\u5ea6\u307e\u305f\u306f\u521d\u671f\u6bb5\u968e\u3067\u8a3a\u65ad\u3055\u308c\u308b\u3053\u3068\u304c\u3088\u304f\u3042\u308a\u307e\u3059\u3002 \u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u5358\u4e00\u306e\u691c\u67fb\u306f\u3042\u308a\u307e\u305b\u3093\u3002 \u533b\u5e2b\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u30c4\u30fc\u30eb\u3092\u4f7f\u7528\u3057\u3066\u8a3a\u65ad\u3092\u884c\u3044\u307e\u3059\u3002 \u6700\u3082\u4e00\u822c\u7684\u306a\u8a3a\u65ad\u65b9\u6cd5\u306b\u306f\u3001\u6b21\u306e\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002 <\/p>\n\n<ul class=\"wp-block-list\"><li>\u7cbe\u795e\u533b\u5b66\u7684\u75c5\u6b74\u304a\u3088\u3073\u8a8d\u77e5\u304a\u3088\u3073\u884c\u52d5\u306e\u5909\u5316\u306e\u75c5\u6b74\u3092\u542b\u3080\u533b\u5b66\u7684\u304a\u3088\u3073\u5bb6\u65cf\u6b74<\/li><li>\u5bb6\u65cf\u306e\u4e00\u54e1\u306e\u601d\u8003\u3068\u884c\u52d5\u306e\u5909\u5316\u306b\u95a2\u3059\u308b\u8aac\u660e<\/li><li>\u8a8d\u77e5\u30c6\u30b9\u30c8\u3068\u8eab\u4f53\u7684\u304a\u3088\u3073\u795e\u7d4c\u5b66\u7684\u691c\u67fb<\/li><li>\u4ed6\u306e\u539f\u56e0\u3092\u9664\u5916\u3059\u308b\u305f\u3081\u306e\u8840\u6db2\u691c\u67fb\u3068\u8133\u753b\u50cf<\/li><li>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u7279\u5fb4\u3067\u3042\u308b\u30d9\u30fc\u30bf\u30a2\u30df\u30ed\u30a4\u30c9\u306e\u30ec\u30d9\u30eb\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306e\u8133\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0<\/li><\/ul>\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"226\" height=\"344\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/The-effect-of-Alzheimers-on-the-brain.png\" alt=\"&#x5065;&#x5EB7;&#x306A;&#x8133;&#x3068;&#x6BD4;&#x8F03;&#x3057;&#x305F;&#x30A2;&#x30EB;&#x30C4;&#x30CF;&#x30A4;&#x30DE;&#x30FC;&#x75C5;&#x306E;&#x8133;\" class=\"wp-image-19693\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/The-effect-of-Alzheimers-on-the-brain.png 226w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2021\/04\/The-effect-of-Alzheimers-on-the-brain-197x300.png 197w\" sizes=\"(max-width: 226px) 100vw, 226px\" \/><figcaption>\u5065\u5eb7\u306a\u8133\uff08\u4e0b\uff09\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30c9\u30ca\u30fc\u306e\u8133\u3002 \u30cf\u30fc\u30bb\u30f3\u30d0\u30f3\u30af\u3002<a href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/3.0\/deed.en\"> 3.0\u79fb\u690d\u3055\u308c\u3066\u3044\u306a\u3044<\/a>\u3002<\/figcaption><\/figure><\/div>\n\n<h2 class=\"wp-block-heading\" id=\"h-treatment-of-alzheimer-s\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6cbb\u7642<\/strong><\/h2>\n\n<p>\u73fe\u5728\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6cbb\u7642\u6cd5\u306f\u3042\u308a\u307e\u305b\u3093\u3002 \u3044\u304f\u3064\u304b\u306e\u85ac\u306f\u75c5\u6c17\u306e\u75c7\u72b6\u3092\u6cbb\u7642\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 <\/p>\n\n<p>\u7c73\u56fd\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u60a3\u8005\u5411\u3051\u306b\u3001\u521d\u671f\u304b\u3089\u4e2d\u671f\u306e\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u963b\u5bb3\u5264\uff08Aricept\u00ae\u3001Exelon\u00ae\u3001Razadyne\u00ae\uff09\u3068\u5f8c\u671f\u306e\u30e1\u30de\u30f3\u30c1\u30f3\uff08Namenda\u00ae\uff09\u306e2\u7a2e\u985e\u306e\u85ac\u5264\u3092\u627f\u8a8d\u3057\u3066\u3044\u307e\u3059\u3002\u8a8d\u77e5\u75c7\u72b6\uff08\u8a18\u61b6\u55aa\u5931\u3001\u6df7\u4e71\u3001\u601d\u8003\u3068\u63a8\u8ad6\u306e\u554f\u984c\uff09\u3002 \u3053\u308c\u3089\u306e\u85ac\u306f\u3001\u8133\u306e\u795e\u7d4c\u7d30\u80de\u9593\u3067\u30e1\u30c3\u30bb\u30fc\u30b8\u3092\u904b\u3076\u3053\u3068\u306b\u95a2\u4e0e\u3059\u308b\u7279\u5b9a\u306e\u5316\u5b66\u7269\u8cea\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u9650\u3089\u308c\u305f\u6642\u9593\u3067\u75c7\u72b6\u3092\u8efd\u6e1b\u307e\u305f\u306f\u5b89\u5b9a\u3055\u305b\u308b\u306e\u306b\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u6642\u3005\u3001\u305d\u308c\u3089\u306f\u4e00\u7dd2\u306b\u53d6\u3089\u308c\u307e\u3059\u3002 <\/p>\n\n<p><a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e4%b8%8d%e5%ae%89-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u4e0d\u5b89<\/a>\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e3%81%86%e3%81%a4%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u3046\u3064\u75c5<\/a>\u3001\u7cbe\u795e\u7684\u82e6\u75db\u3001\u5e7b\u899a\u306a\u3069\u3001\u75c5\u6c17\u306b\u4f34\u3046\u884c\u52d5\u3084\u6027\u683c\u306e\u5909\u5316\u306b\u3064\u3044\u3066\u306f\u3001\u60a3\u8005\u306f\u8eab\u4f53\u7684\u304a\u3088\u3073\u611f\u60c5\u7684\u306a\u5feb\u9069\u3055\u3092\u4fc3\u9032\u3059\u308b\u975e\u85ac\u7269\u6cbb\u7642\u3092\u53d7\u3051\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u9069\u5207\u3067\u3042\u308a\u3001\u533b\u5e2b\u306b\u3088\u3063\u3066\u627f\u8a8d\u3055\u308c\u305f\u5834\u5408\u3001\u4f7f\u7528\u3067\u304d\u308b\u3044\u304f\u3064\u304b\u306e\u85ac\u306b\u306f\u3001\u6297\u3046\u3064\u85ac\u3001\u6297\u4e0d\u5b89\u85ac\u3001\u304a\u3088\u3073\u6297\u7cbe\u795e\u75c5\u85ac\u304c\u542b\u307e\u308c\u307e\u3059\u3002 \u3059\u3079\u3066\u306e\u85ac\u306b\u306f\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n<p>\u8fd1\u5e74\u3001\u521d\u671f\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u53ef\u80fd\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u3001\u591a\u304f\u306e\u65b0\u85ac\u304c\u81e8\u5e8a\u8a66\u9a13\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u3057\u304b\u3057\u3001\u81e8\u5e8a\u7684\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u306f\u3042\u308a\u307e\u305b\u3093\u3002 2020\u5e7411\u6708\u3001FDA\u306f\u6700\u65b0\u306e\u5019\u88dc\u8005\u3092\u627f\u8a8d\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002<a href=\"https:\/\/www.sciencemag.org\/news\/2020\/11\/biogen-s-alzheimer-s-drug-candidate-takes-beating-fda-advisers\">\u30a2\u30c7\u30e5\u30ab\u30cc\u30de\u30d6<\/a>\u3002 FDA\u306f17\u5e74\u9593\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u65b0\u85ac\u3092\u627f\u8a8d\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n<h2 class=\"wp-block-heading\" id=\"h-prognosis-of-alzheimer-s\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u4e88\u5f8c<\/strong><\/h2>\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u4eba\u306e\u4e00\u822c\u7684\u306a\u6b7b\u56e0\u306f\u8aa4\u56a5\u6027\u80ba\u708e\u3067\u3059\u3002\u8aa4\u56a5\u6027\u80ba\u708e\u306f\u3001\u9069\u5207\u306b\u98f2\u307f\u8fbc\u3081\u305a\u3001\u7a7a\u6c17\u3067\u306f\u306a\u304f\u98df\u3079\u7269\u3084\u6db2\u4f53\u3092\u80ba\u306b\u53d6\u308a\u8fbc\u3080\u3068\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n<p>\u75c5\u6c17\u3068\u8a3a\u65ad\u3055\u308c\u3066\u304b\u3089\u306e\u5e73\u5747\u4f59\u547d\u306f\u7d047\u5e74\u304b\u308910\u5e74\u3067\u3059\u304c\u3001\u308f\u305a\u304b4\u5e74\u304b\u30895\u5e74\u3067\u6700\u7d42\u6bb5\u968e\u306b\u9054\u3059\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002 \u4e00\u65b9\u3067\u300120\u5e74\u4ee5\u4e0a\u751f\u304d\u3066\u3044\u308b\u60a3\u8005\u3055\u3093\u3082\u3044\u307e\u3059\u3002 \u5bb6\u65cf\u4ecb\u8b77\u8005\u3084\u53cb\u4eba\u304c\u63d0\u4f9b\u3059\u308b\u652f\u63f4\u30b0\u30eb\u30fc\u30d7\u3084\u30b1\u30a2\u306f\u3001\u9577\u671f\u7684\u306b\u306f\u4e88\u5f8c\u306e\u91cd\u8981\u306a\u8981\u7d20\u3067\u3059\u3002 <\/p>\n\n<p>\u3053\u306e\u8a18\u4e8b\u3092\u697d\u3057\u3093\u3060\u3089\u3001\u4ed6\u306e\u6295\u7a3f\u3092\u30c1\u30a7\u30c3\u30af\u3057\u3066\u304f\u3060\u3055\u3044\u3002<a href=\"https:\/\/nebula.org\/blog\/ja\/nebula-library-unlocking-genetic-research\/\">\u661f\u96f2\u7814\u7a76\u56f3\u66f8\u9928<\/a>\u3002<\/p>\n\n<p>\u6b21\u306e\u3088\u3046\u306a\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u4f34\u3046\u53ef\u80fd\u6027\u306e\u3042\u308b\u72b6\u614b\u306b\u95a2\u3059\u308b\u3053\u308c\u3089\u306e\u8a18\u4e8b\u306b\u7279\u306b\u8208\u5473\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n<ul class=\"wp-block-list\"><li>\u3046\u3064\u75c5\u3084\u305d\u306e\u4ed6\u306e<a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e7%b2%be%e7%a5%9e%e7%97%85-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u7cbe\u795e\u75be\u60a3<\/a><\/li><li><a href=\"https:\/\/nebula.org\/blog\/ja\/is-%e7%b5%b1%e5%90%88%e5%a4%b1%e8%aa%bf%e7%97%87-%e9%81%ba%e4%bc%9d%e7%9a%84\/\">\u7d71\u5408\u5931\u8abf\u75c7<\/a>\uff08\u73fe\u5b9f\u306e\u89e3\u91c8\uff09<\/li><li><a target=\"_blank\" href=\"https:\/\/nebula.org\/blog\/ja\/is-%e3%82%a2%e3%83%ab%e3%82%b3%e3%83%bc%e3%83%ab%e4%be%9d%e5%ad%98%e7%97%87-%e9%81%ba%e4%bc%9d%e7%9a%84\/\" rel=\"noreferrer noopener\">\u30a2\u30eb\u30b3\u30fc\u30eb\u4f9d\u5b58\u75c7<\/a>\uff08\u4f9d\u5b58\u75c7\uff09<\/li><li><a target=\"_blank\" href=\"https:\/\/nebula.org\/blog\/is-bipolar-genetic\/\" rel=\"noreferrer noopener\">\u53cc\u6975\u6027\u969c\u5bb3<\/a>\uff08\u6c17\u5206\u306e\u3080\u3089\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u6c17\u5206\u969c\u5bb3\uff09<\/li><\/ul>\n\n<p 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