{"id":9648,"date":"2021-01-05T23:29:08","date_gmt":"2021-01-06T04:29:08","guid":{"rendered":"https:\/\/nebula.org\/blog\/mrna-%e3%83%a1%e3%83%83%e3%82%bb%e3%83%b3%e3%82%b8%e3%83%a3%e3%83%bc-rna\/"},"modified":"2021-02-20T20:26:52","modified_gmt":"2021-02-21T01:26:52","slug":"mrna-%e3%83%a1%e3%83%83%e3%82%bb%e3%83%b3%e3%82%b8%e3%83%a3%e3%83%bc-rna","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/ja\/mrna-%e3%83%a1%e3%83%83%e3%82%bb%e3%83%b3%e3%82%b8%e3%83%a3%e3%83%bc-rna\/","title":{"rendered":"\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff08mRNA\uff09-\u30b2\u30ce\u30e0\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fc"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-what-is-messenger-rna-mrna\"><strong>\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff08mRNA\uff09\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/strong><\/h2>\n\n<p>\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u307e\u305f\u306fmRNA\u306f\u4e00\u672c\u9396\u30ea\u30dc\u6838\u9178\u3067\u3059\u3002 \u3053\u308c\u306f\u3001\u4e3b\u306b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3059\u308b\u6838\u9178\u306e\u4e00\u7a2e\u3067\u3059\u3002 \u3053\u306e\u5c0f\u5206\u5b50\u306f\u3001\u306e\u30bb\u30af\u30b7\u30e7\u30f3\u306e\u8ee2\u5199\u7269\u3067\u3059<a href=\"https:\/\/nebula.org\/blog\/ja\/dna-%e3%83%87%e3%82%aa%e3%82%ad%e3%82%b7%e3%83%aa%e3%83%9c%e6%a0%b8%e9%85%b8\/\">DNA<\/a>\u30b7\u30fc\u30b1\u30f3\u30b9\u3002 mRNA\u306b\u306f\u3001\u7d30\u80de\u5185\u3067\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u751f\u7523\u306b\u95a2\u3059\u308b\u60c5\u5831\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n<p>\u30c7\u30aa\u30ad\u30b7\u30ea\u30dc\u6838\u9178\u306e\u7279\u5b9a\u306e\u30bb\u30af\u30b7\u30e7\u30f3\u306f\u3001\u9175\u7d20RNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u306b\u3088\u3063\u3066RNA\u306b\u767a\u73fe\u3055\u308c\u307e\u3059\uff08<a href=\"https:\/\/nebula.org\/blog\/ja\/dna-%e3%83%9d%e3%83%aa%e3%83%a1%e3%83%a9%e3%83%bc%e3%82%bc\/\"> DNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc<\/a>DNA\u3092\u30b3\u30d4\u30fc\u3057\u307e\u3059\uff09\u3002 \u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u3001\u8ee2\u5199\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u4e2d\u3001\u30ea\u30dc\u30bd\u30fc\u30e0\u30bf\u30f3\u30d1\u30af\u8cea\u751f\u5408\u6210\u306e\u30c6\u30f3\u30d7\u30ec\u30fc\u30c8\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002 \u6700\u7d42\u7684\u306b\u3001\u3053\u308c\u306f\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u9396\u5408\u6210\u3078\u306e\u9053\u3092\u958b\u304d\u307e\u3059\u3002<\/p>\n\n<p> \u306e\u5834\u5408<a href=\"https:\/\/www.nature.com\/articles\/nrd4278\">mRNA\u30d9\u30fc\u30b9\u306e\u85ac<\/a>\u3001\u7d30\u80de\u306f\u914d\u5217\u60c5\u5831\u306b\u5f93\u3063\u3066\u6d3b\u6027\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u7523\u751f\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002 RNA\u30d9\u30fc\u30b9\u306e\u30ef\u30af\u30c1\u30f3\u306e\u5834\u5408\u3001\u3053\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u6297\u539f\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n<figure class=\"wp-block-table\"><table class=\"has-subtle-pale-pink-background-color has-background\"><tbody><tr><td><a href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\"><strong>DNA\u3092100\uff05\u30c7\u30b3\u30fc\u30c9\u3059\u308b\u3053\u3068\u306b\u8208\u5473\u304c\u3042\u308a\u307e\u3059\u304b\uff1f Nebula Genomics\u306f\u3001\u6700\u3082\u624b\u9803\u306a\u5168\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b9\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002 \u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u3078\u306e\u30d5\u30eb\u30a2\u30af\u30bb\u30b9\u3001\u6700\u65b0\u306e\u79d1\u5b66\u7684\u767a\u898b\u306b\u57fa\u3065\u304f\u6bce\u9031\u306e\u66f4\u65b0\u3001\u9ad8\u5ea6\u306a\u7956\u5148\u5206\u6790\u3001\u304a\u3088\u3073\u5f37\u529b\u306a\u30b2\u30ce\u30e0\u63a2\u7d22\u30c4\u30fc\u30eb\u3092\u4f7f\u7528\u3057\u3066\u3001\u4e00\u751f\u306e\u767a\u898b\u3092\u958b\u59cb\u3057\u307e\u3059\u3002 \u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong><\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n<p><em>Christina Swords\u3001Ph.D\u3002\u304c\u7de8\u96c6<\/em><\/p>\n\n<h2 class=\"wp-block-heading\" id=\"h-transcription\"><strong>\u8ee2\u5199<\/strong><\/h2>\n\n<p>\u4e2d<a href=\"https:\/\/www.nature.com\/scitable\/definition\/transcription-dna-transcription-87\/\">\u8ee2\u5199<\/a>\u3001\u907a\u4f1d\u6697\u53f7\u306e\u30bb\u30af\u30b7\u30e7\u30f3\u306f\u3001RNA\u306e\u4e00\u672c\u9396\u306b\u8ee2\u5199\u3055\u308c\u307e\u3059\u3002 \u3053\u306e\u3088\u3046\u306a\u30bb\u30af\u30b7\u30e7\u30f3\u306f\u3001\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u9818\u57df\u3068\u547c\u3070\u308c\u307e\u3059\u3002 \u3053\u308c\u306f\u3001\u9175\u7d20RNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u306e\u4f5c\u7528\u4e0b\u3067\u8d77\u3053\u308a\u307e\u3059\u3002 <\/p>\n\n<p>\u30b3\u30fc\u30c9DNA\u9396\u306f\u3001RNA\u9396\u3092\u69cb\u7bc9\u3059\u308b\u305f\u3081\u306e\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002 \u5408\u6210\u3055\u308c\u305fmRNA\u306f\u3001\u7ffb\u8a33\u306e\u904e\u7a0b\u3067\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u307e\u3059\u3002 <\/p>\n\n<p>\u539f\u6838\u751f\u7269\u306f\u6838\u3092\u6301\u305f\u305a\u3001\u7d30\u80de\u8cea\u3067\u8ee2\u5199\u3092\u793a\u3057\u307e\u3059\u3002 \u771f\u6838\u751f\u7269\u306b\u3044\u308b\u9593\u3001\u6838\u30b2\u30ce\u30e0\u306f\u7d30\u80de\u6838\u306e\u6838\u8cea\u306b\u8ee2\u5199\u3055\u308c\u307e\u3059\u3002<\/p>\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh3.googleusercontent.com\/aB-8PlXJ8hQjpzC8hrOHE3hvW9fkc5jHsbiWbpek9mgtLUZUDNlkHu1y95TTmyE273NsgRM2oiLljE9L10kSxfwHefW9mTFjQcSbxiCbRYnYgrmnLYO_sQjGDFOaDUZ4ZFsJfFj4\" alt=\"mRNA&#x5F62;&#x6210;&#x306E;&#x7C21;&#x5358;&#x306A;&#x30EF;&#x30FC;&#x30AF;&#x30D5;&#x30ED;&#x30FC;&#x3002;\" title=\"mRNA&#x5408;&#x6210;\"\/><figcaption>\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff08mRNA\uff09\u5f62\u6210\u306e\u7c21\u7565\u5316\u3055\u308c\u305f\u30d5\u30ed\u30fc\u3002 \u753b\u50cf\u30bd\u30fc\u30b9\uff1aDovelike\u3001\u30a6\u30a3\u30ad\u30e1\u30c7\u30a3\u30a2\u30b3\u30e2\u30f3\u30baCC-BY-SA 3.0<\/figcaption><\/figure>\n\n<p>\u539f\u6838\u751f\u7269\u3067\u306f\u3001\u30ea\u30dc\u30bd\u30fc\u30e0\u306f\u307e\u3060\u5b8c\u5168\u306b\u5408\u6210\u3055\u308c\u3066\u3044\u306a\u3044mRNA\u914d\u5217\u306b\u3059\u3067\u306b\u4ed8\u7740\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u305d\u3057\u3066\u3001\u7ffb\u8a33\u3092\u958b\u59cb\u3057\u307e\u3059\u3002 \u3057\u305f\u304c\u3063\u3066\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5408\u6210\u306f\u8ee2\u5199\u3068\u540c\u6642\u306b\u958b\u59cb\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u3053\u308c\u306b\u3088\u308a\u7279\u6b8a\u306a\u5f62\u614b\u306e<a href=\"https:\/\/nebula.org\/blog\/ja\/%e9%81%ba%e4%bc%9d%e5%ad%90\/\">\u907a\u4f1d\u5b50<\/a>\u898f\u5236\u3002 <\/p>\n\n<p>\u771f\u6838\u751f\u7269\u3067\u306f\u3001\u4e00\u6b21RNA\u8ee2\u5199\u7523\u7269\u306f\u6700\u521d\u306b\u7d30\u80de\u6838\u5185\u3067\u3055\u307e\u3056\u307e\u306a\u30d7\u30ed\u30bb\u30b9\u306b\u3055\u3089\u3055\u308c\u307e\u3059\u3002 \u305d\u3046\u3057\u3066\u521d\u3081\u3066\u3001\u305d\u308c\u306f\u6838\u304b\u3089mRNA\u3068\u3057\u3066\u30ea\u30dc\u30bd\u30fc\u30e0\u304c\u4f4d\u7f6e\u3059\u308b\u7d30\u80de\u8cea\u306b\u8f38\u9001\u3055\u308c\u307e\u3059\u3002<\/p>\n\n<p>\u539f\u6838\u751f\u7269\u306f\u3001RNA\u5408\u6210\u306e\u305f\u3081\u306b1\u7a2e\u985e\u306eRNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u3057\u304b\u6301\u3063\u3066\u3044\u307e\u305b\u3093\u3002 \u5bfe\u7167\u7684\u306b\u3001\u771f\u6838\u751f\u7269\u306f\u3055\u307e\u3056\u307e\u306a\u7a2e\u985e\u306eRNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002 \u305d\u3057\u3066\u4e3b\u306bRNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bcII\u306f\u30d7\u30ecmRNA\u306e\u5408\u6210\u3092\u89e6\u5a92\u3057\u307e\u3059\u3002<\/p>\n\n<p>\u539f\u6838\u751f\u7269\u3068\u771f\u6838\u751f\u7269\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306e\u4e3b\u306a\u9055\u3044\u306f\u3001\u539f\u6838\u751f\u7269\u306emRNA\u306f\u901a\u5e38\u30dd\u30ea\u30b7\u30b9\u30c8\u30ed\u30f3\u6027\u3067\u3042\u308b\u306e\u306b\u5bfe\u3057\u3001\u771f\u6838\u751f\u7269\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306f\u901a\u5e38\u30e2\u30ce\u30b7\u30b9\u30c8\u30ed\u30f3\u6027\u3067\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002 \u3053\u308c\u306b\u3088\u308a\u3001\u539f\u6838\u751f\u7269\u306f1\u3064\u306emRNA\u8ee2\u5199\u7523\u7269\u306b\u95a2\u3059\u308b\u8907\u6570\u306e\u907a\u4f1d\u5b50\u306e\u60c5\u5831\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u3057\u305f\u304c\u3063\u3066\u3001\u30b3\u30fc\u30c9\u3055\u308c\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5408\u6210\u3068mRNA\u5408\u6210\u306f\u540c\u6642\u306b\u8d77\u3053\u308a\u307e\u3059\u3002 DNA\u4e0a\u306e\u6a5f\u80fd\u7684\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u305d\u306e\u3088\u3046\u306a\u5171\u540c\u8ee2\u5199\u9818\u57df\u306e1\u3064\u306f\u30aa\u30da\u30ed\u30f3\u3068\u547c\u3070\u308c\u307e\u3059\u3002<\/p>\n\n<h3 class=\"wp-block-heading\" id=\"h-eukaryotic-pre-messenger-rna-pre-mrna-processing\"><strong>\u771f\u6838\u751f\u7269\u306e\u30d7\u30ec\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff08pre-mRNA\uff09\u30d7\u30ed\u30bb\u30c3\u30b7\u30f3\u30b0<\/strong><\/h3>\n\n<p>\u771f\u6838\u7d30\u80de\u3067\u306f\u3001\u6210\u719f\u3057\u305f\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306f<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK21563\/\">\u51e6\u7406<\/a>\u305d\u306e\u524d\u99c6\u4f53\u3002 \u524d\u99c6\u4f53\u306f\u3001hnRNA\uff08\u7570\u7a2e\u6838RNA\uff09\u307e\u305f\u306f\u30d7\u30ecmRNA\uff08\u524d\u99c6\u4f53\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u3001\u30d7\u30ecmRNA\uff09\u3068\u547c\u3070\u308c\u307e\u3059\u3002 <\/p>\n\n<p>\u3053\u308c\u3089\u306e\u30b9\u30c6\u30c3\u30d7\u306f\u7d30\u80de\u6838\u3067\u884c\u308f\u308c\u307e\u3059\u3002 \u6b21\u306b\u3001mRNA\u306f\u6838\u819c\u5b54\u3092\u901a\u3063\u3066\u7d30\u80de\u8cea\u306b\u5165\u308a\u307e\u3059\u3002 \u305d\u3057\u3066\u6700\u7d42\u7684\u306b\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u751f\u5408\u6210\u306f\u30ea\u30dc\u30bd\u30fc\u30e0\u3092\u4ecb\u3057\u3066\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n\n<ul class=\"wp-block-list\"><li><strong>\u30ad\u30e3\u30c3\u30d4\u30f3\u30b0<\/strong>\uff1aRNA\u5206\u5b50\u306e5 &#8216;\u672b\u7aef\u306f5&#8217;\u30ad\u30e3\u30c3\u30d7\u69cb\u9020\u306b\u306a\u308a\u307e\u3059\u3002 \u3053\u306e\u30ad\u30e3\u30c3\u30d7\u306f\u3001\u30b0\u30a2\u30ce\u30b7\u30f3\u306e\u4fee\u98fe\u578b\u3067\u3042\u308b7-\u30e1\u30c1\u30eb\u30b0\u30a2\u30ce\u30b7\u30f3\uff08m7G\uff09\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u30ad\u30e3\u30c3\u30d7\u306f\u3001\u30cc\u30af\u30ec\u30a2\u30fc\u30bc\u306b\u3088\u308b\u5206\u89e3\u304b\u3089RNA\u3092\u4fdd\u8b77\u3057\u3001\u30ad\u30e3\u30c3\u30d7\u7d50\u5408\u8907\u5408\u4f53\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059\u3002 \u3053\u308c\u306f\u3001\u3068\u308a\u308f\u3051\u6838\u5916\u8f38\u9001\u306b\u3068\u3063\u3066\u91cd\u8981\u3067\u3059\u3002 \u30b5\u30a4\u30c8\u30be\u30eb\u306b\u8f38\u9001\u3055\u308c\u305f\u5f8c\u3001\u30ad\u30e3\u30c3\u30d7\u306fmRNA\u306e\u8a8d\u8b58\u3092\u52a9\u3051\u307e\u3059\u3002 \u305d\u308c\u306f\u5c0f\u3055\u306a\u30ea\u30dc\u30bd\u30fc\u30e0\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u306e\u52a9\u3051\u3092\u501f\u308a\u3066\u305d\u3046\u3057\u307e\u3059\u3002 \u3053\u308c\u306f\u3001\u7ffb\u8a33\u3092\u958b\u59cb\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/li><li><strong>\u30dd\u30ea\u30a2\u30c7\u30cb\u30eb\u5316<\/strong>\uff1aRNA\u306f3 &#8216;\u672b\u7aef\u3067\u30dd\u30ea\u30a2\u30c7\u30cb\u30eb\u5316\u3092\u53d7\u3051\u307e\u3059\u3002 \u3053\u306e\u30d7\u30ed\u30bb\u30b9\u4e2d\u306b\u300130\u301c200\u500b\u306e\u30a2\u30c7\u30cb\u30f3\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u304b\u3089\u306a\u308b\u30dd\u30eaA\u30c6\u30fc\u30eb\u304c\u4ed8\u7740\u3057\u307e\u3059\u3002 \u3053\u308c\u306f\u307e\u305f\u3001\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u3092\u9175\u7d20\u5206\u89e3\u304b\u3089\u4fdd\u8b77\u3057\u307e\u3059\u3002 \u3055\u3089\u306b\u3001\u6838\u5916\u8f38\u9001\u3068mRNA\u306e\u7ffb\u8a33\u306e\u4e21\u65b9\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<\/li><li><strong>\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0<\/strong>\uff1a\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u306f\u3001\u30a4\u30f3\u30c8\u30ed\u30f3\u3068\u547c\u3070\u308c\u308b\u5143\u306e\u8ee2\u5199\u7523\u7269\u304b\u3089\u7279\u5b9a\u306eRNA\u30bb\u30b0\u30e1\u30f3\u30c8\u3092\u524a\u9664\u3057\u307e\u3059\u3002 \u30a4\u30f3\u30c8\u30ed\u30f3\u306f\u901a\u5e38\u3001\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u60c5\u5831\u306b\u8ca2\u732e\u3057\u307e\u305b\u3093\u3002 \u6b8b\u308a\u306e\u30bb\u30b0\u30e1\u30f3\u30c8\u306f\u30a8\u30af\u30bd\u30f3\u3068\u3057\u3066\u7d50\u5408\u3055\u308c\u307e\u3059\u3002 \u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u30b9\u30d7\u30e9\u30a4\u30bb\u30aa\u30bd\u30fc\u30e0\u3067\u884c\u308f\u308c\u307e\u3059\u3002 <\/li><\/ul>\n\n<p>\u30b9\u30d7\u30e9\u30a4\u30bb\u30aa\u30bd\u30fc\u30e0\u306f\u3001hnRNA\u3068\u3044\u308f\u3086\u308bsnRNP\uff08\u6838\u5185\u4f4e\u5206\u5b50\u30ea\u30dc\u6838\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u306e\u8907\u5408\u4f53\u3067\u3059\u3002 \u30b9\u30d7\u30e9\u30a4\u30bb\u30aa\u30bd\u30fc\u30e0\u306f\u3001snRNA U1\u3001U2\u3001U4\u3001U5\u3001\u304a\u3088\u3073U6\u3068\u7d0450\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u3057\u305f\u304c\u3063\u3066\u3001\u9078\u629e\u7684\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u306b\u3088\u308a\u3001\u540c\u3058hnRNA\u304b\u3089\u7570\u306a\u308bmRNA\u3092\u751f\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u3053\u308c\u3089\u306e\u7d50\u679c\u3092\u7ffb\u8a33\u3059\u308b\u3068\u3001\u3055\u307e\u3056\u307e\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n<figure class=\"wp-block-image is-resized\"><img decoding=\"async\" src=\"https:\/\/lh3.googleusercontent.com\/g7jG2MVmk25xAgfURqcGQ5vTZlnZNnKmL05kPuG6-k2f2TTVF6R1lFln9QdTu69zpNHsNtPwdXRoPYsDUB6ZqQzMewkfYn-5iyM_V02wyazjPyhZ3UtIoZThH3e-Svzed7F208LW\" alt=\"&#x30E1;&#x30C3;&#x30BB;&#x30F3;&#x30B8;&#x30E3;&#x30FC;RNA&#xFF08;mRNA&#xFF09;&#x306E;&#x751F;&#x6210;&#x3092;&#x52A9;&#x3051;&#x308B;&#x30B9;&#x30D7;&#x30E9;&#x30A4;&#x30BB;&#x30AA;&#x30BD;&#x30FC;&#x30E0;&#x8907;&#x5408;&#x4F53;&#x3002;\" width=\"296\" height=\"287\" title=\"&#x30B9;&#x30D7;&#x30E9;&#x30A4;&#x30BB;&#x30AA;&#x30BD;&#x30FC;&#x30E0;&#x30A2;&#x30BB;&#x30F3;&#x30D6;&#x30EA;\"\/><figcaption>\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306e\u751f\u6210\u3092\u52a9\u3051\u308b\u30b9\u30d7\u30e9\u30a4\u30bb\u30aa\u30bd\u30fc\u30e0\u8907\u5408\u4f53\u3002 \u753b\u50cf\u30bd\u30fc\u30b9\uff1aAgathman\u3001\u30a6\u30a3\u30ad\u30e1\u30c7\u30a3\u30a2\u30b3\u30e2\u30f3\u30ba\u3001CC-BY-SA 3.0<\/figcaption><\/figure>\n\n<p>\u3053\u308c\u306f\u3001\u7d30\u80de\u306e\u3055\u307e\u3056\u307e\u306a\u8abf\u7bc0\u30d7\u30ed\u30bb\u30b9\u304c\u4ecb\u5165\u3059\u308b\u5834\u6240\u3067\u3082\u3042\u308a\u307e\u3059\u3002 \u30a2\u30f3\u30c1\u30bb\u30f3\u30b9RNA\u304a\u3088\u3073RNA\u5e72\u6e09\u3092\u4f7f\u7528\u3057\u3066mRNA\u3092\u5206\u89e3\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u3057\u305f\u304c\u3063\u3066\u3001\u3053\u308c\u306f\u7ffb\u8a33\u3092\u9632\u304e\u307e\u3059\u3002<\/p>\n\n<p>\u3055\u3089\u306b\u3001\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306e\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306f\u3001RNA\u7de8\u96c6\u30d7\u30ed\u30bb\u30b9\u306b\u3088\u3063\u3066\u5909\u66f4\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002 \u4f8b\u3068\u3057\u3066\u3001\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8ceaB\u306emRNA\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u4e00\u90e8\u306e\u7d44\u7e54\u3067\u306f\u3001\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8ceaB\u306emRNA\u3092\u7de8\u96c6\u3059\u308b\u3068\u3001\u4e0a\u6d41\u306b2\u756a\u76ee\u306e\u7d42\u6b62\u30b3\u30c9\u30f3\u304c\u4f5c\u6210\u3055\u308c\u307e\u3059\u3002 \u3053\u308c\u306f\u3001\u7570\u306a\u308b\u6a5f\u80fd\u3092\u6301\u3064\u3088\u308a\u77ed\u3044\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u307e\u3059\u3002 <\/p>\n\n<p>mRNA\u306e\u975e\u7ffb\u8a33\u9818\u57df\u3082\u3001\u7ffb\u8a33\u3060\u3051\u3067\u306a\u304f\u8ee2\u5199\u306e\u8abf\u7bc0\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<h2 class=\"wp-block-heading\" id=\"h-translation\"><strong>\u7ffb\u8a33<\/strong><\/h2>\n\n<p>\u7ffb\u8a33\u4e2d\u306b\u3001mRNA\u306e\u6838\u9178\u5869\u57fa\u306e\u30b3\u30fc\u30c9\u914d\u5217\u304c\u30a2\u30df\u30ce\u9178\u914d\u5217\u306b\u7ffb\u8a33\u3055\u308c\u307e\u3059\u3002 \u3053\u308c\u306b\u3088\u308a\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u9396\u306e1\u3064\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002 <\/p>\n\n<p>\u30aa\u30fc\u30d7\u30f3\u30ea\u30fc\u30c7\u30a3\u30f3\u30b0\u30d5\u30ec\u30fc\u30e0\u306e\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u914d\u5217\u306f\u30c8\u30ea\u30d7\u30ec\u30c3\u30c8\u3067\u8aad\u307f\u53d6\u3089\u308c\u307e\u3059\u3002 \u5404\u5869\u57fa\u30c8\u30ea\u30d7\u30ec\u30c3\u30c8\u306b\u306f\u3001\u30c8\u30e9\u30f3\u30b9\u30d5\u30a1\u30fcRNA\u307e\u305f\u306ftRNA\u5206\u5b50\u306b\u3088\u3063\u3066\u7279\u5b9a\u306e\u30a2\u30df\u30ce\u9178\u304c\u5272\u308a\u5f53\u3066\u3089\u308c\u307e\u3059\u3002 \u6b21\u306b\u3001\u3053\u308c\u3089\u306f\u30da\u30d7\u30c1\u30c9\u7d50\u5408\u3092\u4ecb\u3057\u3066\u524d\u306e\u3082\u306e\u306b\u30ea\u30f3\u30af\u3055\u308c\u307e\u3059\u3002 \u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u7d30\u80de\u8cea\u306e\u30ea\u30dc\u30bd\u30fc\u30e0\u3067\u8d77\u3053\u308a\u3001\u5b9f\u969b\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u751f\u5408\u6210\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n<p>\u771f\u6838\u7d30\u80de\u3067\u306f\u3001\u30ea\u30dc\u30bd\u30fc\u30e0\u306f\u904a\u96e2\u3057\u3066\u3044\u308b\u304b\u3001\u5c0f\u80de\u4f53\u306e\u819c\u306b\u4ed8\u7740\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n<figure class=\"wp-block-image is-resized\"><img decoding=\"async\" src=\"https:\/\/lh5.googleusercontent.com\/QPX5XYv5w6wGpCmzCVMMl5o4lmPSdSJTuRqOE0JjaOqA6GJhViM6SOUrA7dh-ff1ahId5jDkFjARXRomgOmjHg8RKhcrBvh3Cxh8KpT1ZDoWyEKL6iburh7BLOeuhsKvtsYTaJmJ\" alt=\"DNA&#x304B;&#x3089;&#x30BF;&#x30F3;&#x30D1;&#x30AF;&#x8CEA;&#x3078;&#x306E;&#x7FFB;&#x8A33;&#x3002;\" width=\"480\" height=\"300\" title=\"DNA&#x304B;&#x3089;&#x30BF;&#x30F3;&#x30D1;&#x30AF;&#x8CEA;&#x3078;&#x306E;&#x7FFB;&#x8A33;\"\/><figcaption>DNA\u304b\u3089mRNA\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3078\u306e\u7ffb\u8a33\u3002 \u753b\u50cf\u30bd\u30fc\u30b9\uff1a\u30d9\u30c3\u30ad\u30fc\u30d6\u30fc\u30f3\u3001\u30a6\u30a3\u30ad\u30e1\u30c7\u30a3\u30a2\u30b3\u30e2\u30f3\u30ba\u3001CC-BY-SA 2.0<br\/><\/figcaption><\/figure>\n\n<p>\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306b\u7d50\u5408\u3059\u308b\u3068\u3001\u30ea\u30dc\u30bd\u30fc\u30e0\u306fmRNA\u306e\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u914d\u5217\u3092\u7ffb\u8a33\u3057\u307e\u3059\u3002 \u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u30b3\u30fc\u30c9\u3092\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5bfe\u5fdc\u3059\u308b\u30a2\u30df\u30ce\u9178\u914d\u5217\u306b\u5909\u63db\u3057\u307e\u3059\u3002 <\/p>\n\n<p>\u5fc5\u8981\u306a\u30a2\u30df\u30ce\u9178\u5206\u5b50\u306f\u3001\u7d30\u80de\u8cea\u304b\u3089\u306etRNA\u5206\u5b50\u306b\u3088\u3063\u3066\u904b\u3070\u308c\u307e\u3059\u3002 \u539f\u6838\u751f\u7269\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306b\u306f\u3001\u591a\u304f\u306e\u5834\u5408\u3001\u3044\u304f\u3064\u304b\u306e\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u30bb\u30af\u30b7\u30e7\u30f3\uff08\u30dd\u30ea\u30b8\u30fc\u30f3mRNA\uff09\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002 \u9006\u306b\u3001\u771f\u6838\u751f\u7269\u306emRNA\u306f\u30e2\u30ce\u30b7\u30b9\u30c8\u30ed\u30f3\u6027\u3067\u3042\u308a\u3001\u30b3\u30fc\u30c9\u914d\u5217\u3092\u6301\u3064\u30bb\u30af\u30b7\u30e7\u30f3\u304c1\u3064\u3060\u3051\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<p>\u30ea\u30dc\u30bd\u30fc\u30e0\u306f\u3001\u4e00\u5ea6\u306b1\u3064\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\u306e\u307f\u3092\u7ffb\u8a33\u3057\u307e\u3059\u3002 \u6b21\u306b\u3001\u30ea\u30dc\u30bd\u30fc\u30e0\u304cmRNA\u304b\u3089\u5206\u96e2\u3057\u307e\u3059\u3002 \u305f\u3060\u3057\u3001\u8907\u6570\u306e\u30ea\u30dc\u30bd\u30fc\u30e0\u304c\u540c\u6642\u306b1\u3064\u306emRNA\u306b\u4ed8\u7740\u3057\u3001\u305d\u308c\u305e\u308c1\u3064\u306e\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u9396\u3092\u5408\u6210\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 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