{"id":9758,"date":"2021-01-05T23:59:33","date_gmt":"2021-01-06T04:59:33","guid":{"rendered":"https:\/\/nebula.org\/blog\/%e8%84%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e5%b0%8f%e8%a1%80%e7%ae%a1-%e7%97%85%e6%b0%97-chung-2019\/"},"modified":"2021-02-20T20:49:43","modified_gmt":"2021-02-21T01:49:43","slug":"%e8%84%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e5%b0%8f%e8%a1%80%e7%ae%a1-%e7%97%85%e6%b0%97-chung-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/ja\/%e8%84%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e5%b0%8f%e8%a1%80%e7%ae%a1-%e7%97%85%e6%b0%97-chung-2019\/","title":{"rendered":"\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\uff08Chung\u30012019\uff09"},"content":{"rendered":"\n<p><strong>\u7814\u7a76\u30bf\u30a4\u30c8\u30eb\uff1a<\/strong><a href=\"https:\/\/academic.oup.com\/brain\/article-abstract\/142\/10\/3176\/5552330?redirectedFrom=fulltext\">\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\uff08CSVD\uff09\u306e\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u7814\u7a76\u306b\u3088\u308a\u3001\u78ba\u7acb\u3055\u308c\u305f\u65b0\u898f\u907a\u4f1d\u5b50\u5ea7\u304c\u660e\u3089\u304b\u306b<\/a><\/p>\n\n<p><strong>\u6982\u8981\uff1a<\/strong>\u3055\u307e\u3056\u307e\u306a\u8a8d\u77e5\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\u306b\u95a2\u9023\u3059\u308b\u65b0\u898f\u306e\u907a\u4f1d\u7684\u5909\u7570\u306e\u540c\u5b9a\u3002<\/p>\n\n<p><strong>\u8aac\u660e\uff1a<\/strong>\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\uff08CSVD\uff09\u306f\u3001\u8133\u5185\u306e\u5c0f\u8840\u7ba1\u306e\u7570\u5e38\u3084\u640d\u50b7\u306b\u95a2\u9023\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u72b6\u614b\u3092\u8868\u3057\u307e\u3059\u3002 \u6700\u3082\u4e00\u822c\u7684\u306a\u72b6\u614b\u306e\u3044\u304f\u3064\u304b\u306f\u3001\u786c\u5316\u3057\u305f\u8840\u7ba1\u306e\u7d50\u679c\u3067\u3042\u308b\u5c0f\u8840\u7ba1\u865a\u8840\u6027\u8133\u5352\u4e2d\u3001\u304a\u3088\u3073\u8133\u5185\u306e\u8840\u7ba1\u304c\u7834\u88c2\u3057\u305f\u3068\u304d\u306b\u767a\u751f\u3059\u308b\u8133\u5185\u51fa\u8840\u3067\u3059\u3002 CSVD\u306f\u4e00\u822c\u306b\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3001\u904b\u52d5\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u3046\u3064\u75c5\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 CSVD\u306e\u767a\u75c7\u3068\u76f8\u95a2\u3059\u308b\u907a\u4f1d\u7684\u5909\u7570\u306f\u307b\u3068\u3093\u3069\u767a\u898b\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002 \u3053\u306e\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u7814\u7a76\u3067\u306f\u300124\u4e07\u4eba\u3092\u8d85\u3048\u308b\u4eba\u3005\u306e\u907a\u4f1d\u30c7\u30fc\u30bf\u3092\u8a55\u4fa1\u3057\u3066\u3001CSVD\u306e\u30ea\u30b9\u30af\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u907a\u4f1d\u7684\u8981\u56e0\u3092\u3088\u308a\u9069\u5207\u306b\u7279\u5b9a\u3057\u307e\u3059\u3002 \u8907\u6570\u306e\u65b0\u3057\u3044\u5909\u7570\u4f53\u304c\u767a\u898b\u3055\u308c\u307e\u3057\u305f\u304c\u3001\u4ee5\u524d\u306f\u8133\u3084\u8840\u7ba1\u306e\u969c\u5bb3\u306b\u95a2\u9023\u3057\u3066\u3044\u305f\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002 \u305f\u3068\u3048\u3070\u3001PMF1\u907a\u4f1d\u5b50\u306f\u3001\u8133\u3092\u4fdd\u8b77\u3059\u308b\u8840\u6db2\u8133\u95a2\u9580\u306e\u7834\u58ca\u306b\u95a2\u9023\u3057\u3066\u304a\u308a\u3001COL4A2\u907a\u4f1d\u5b50\u306f\u3001\u8133\u306e\u8840\u7ba1\u306e\u5185\u9762\u306b\u5c64\u3092\u5f62\u6210\u3057\u3001\u8840\u6d41\u306e\u8abf\u7bc0\u3092\u52a9\u3051\u308b\u7d30\u80de\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n<p><strong>\u77e5\u3063\u3066\u307e\u3059\u304b\uff1f<\/strong>\u8840\u5727\u3092\u4e0b\u3052\u308b\u3068\u3001CSVD\u3092\u542b\u3080\u591a\u304f\u306e\u7a2e\u985e\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e88\u9632\u306b\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e88\u9632\u7b56\u306b\u306f\u3001\u5b9a\u671f\u7684\u306a\u904b\u52d5\u3001\u5065\u5eb7\u7684\u306a\u98df\u4e8b\u3001\u51e6\u65b9\u3055\u308c\u305f\u8840\u5727\u85ac\u306e\u670d\u7528\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002 [<a href=\"https:\/\/www.healthline.com\/health\/microvascular-ischemic-disease\">\u30bd\u30fc\u30b9<\/a>]<\/p>\n\n<p><strong>\u30b5\u30f3\u30d7\u30eb\u7d50\u679c\uff1a<\/strong>\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/nebula-library-unlocking-genetic-research\/\">\u661f\u96f2\u7814\u7a76\u56f3\u66f8\u9928<\/a>\u3002<\/p>\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/nebula.org\/free-dna-upload-analysis\/\"><img decoding=\"async\" src=\"http:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png\" alt=\"&#x3053;&#x306E;&#x753B;&#x50CF;&#x306B;&#x306F;&#x7A7A;&#x306E;alt&#x5C5E;&#x6027;&#x304C;&#x3042;&#x308A;&#x307E;&#x3059;&#x3002;&#x305D;&#x306E;&#x30D5;&#x30A1;&#x30A4;&#x30EB;&#x540D;&#x306F;Nebula-personalized-results-genomics-1024x375.png&#x3067;&#x3059;&#x3002;\"\/><\/a><\/figure>\n\n<p><\/p>\n\n<p><strong>CSVD\u95a2\u9023\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\uff1a<\/strong> rs9515201\u3001rs72932727\u3001rs2758605<\/p>\n\n<p><strong>\u8ffd\u52a0\u306e\u30ea\u30bd\u30fc\u30b9\uff1a<\/strong><br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/www.nextavenue.org\/common-aging-brain-problem\/\" target=\"_blank\">\u8133\u5c0f\u8840\u7ba1\u75be\u60a3<\/a><br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/en.wikipedia.org\/wiki\/Cerebral_circulation\" target=\"_blank\">\u8133\u306e\u5faa\u74b0\u5668\u7cfb<\/a><\/p>\n\n<p><strong>\u6bce\u9031\u306e\u66f4\u65b0\uff1a<\/strong> 2019\u5e748\u670830\u65e5<\/p>\n\n<p><\/p>\n\n<p><\/p>\n\n<p><\/p>\n\n<p><\/p>\n\n<p><br\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u30bf\u30a4\u30c8\u30eb\uff1a\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\uff08CSVD\uff09\u306e\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u7814\u7a76\u306b\u3088\u308a\u3001\u78ba\u7acb\u3055\u308c\u305f\u65b0 &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/ja\/%e8%84%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-%e5%b0%8f%e8%a1%80%e7%ae%a1-%e7%97%85%e6%b0%97-chung-2019\/\"> <span class=\"screen-reader-text\">\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\uff08Chung\u30012019\uff09<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":5472,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4981],"tags":[],"class_list":["post-9758","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-4981"],"yoast_head":"<!-- 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