{"id":9789,"date":"2021-01-06T00:00:42","date_gmt":"2021-01-06T05:00:42","guid":{"rendered":"https:\/\/nebula.org\/blog\/%e8%85%8e%e8%87%93%e7%b5%90%e7%9f%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-thorleifsson-2009\/"},"modified":"2021-02-20T20:33:15","modified_gmt":"2021-02-21T01:33:15","slug":"%e8%85%8e%e8%87%93%e7%b5%90%e7%9f%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-thorleifsson-2009","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/ja\/%e8%85%8e%e8%87%93%e7%b5%90%e7%9f%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-thorleifsson-2009\/","title":{"rendered":"\u814e\u81d3\u7d50\u77f3\uff08Thorleifsson\u30012009\u5e74\uff09"},"content":{"rendered":"\n<p><strong>\u7814\u7a76\u30bf\u30a4\u30c8\u30eb\uff1a<\/strong><a href=\"https:\/\/www.nature.com\/articles\/ng.404\"> CLDN14\u907a\u4f1d\u5b50\u306e\u914d\u5217\u5909\u7570\u4f53\u306f\u814e\u81d3\u7d50\u77f3\u3068\u9aa8\u5869\u5bc6\u5ea6\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059<\/a><\/p>\n\n<p><strong>\u6982\u8981\uff1a<\/strong>\u814e\u81d3\u7d50\u77f3\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u306f\u3001CLDN14\u907a\u4f1d\u5b50\u306e\u907a\u4f1d\u7684\u5909\u7570\u306b\u3088\u3063\u3066\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n\n<p><strong>\u8aac\u660e\uff1a<\/strong>\u814e\u81d3\u7d50\u77f3\u75c7\u306f\u3001\u30df\u30cd\u30e9\u30eb\u3068\u5869\uff08\u901a\u5e38\u306f\u30b7\u30e5\u30a6\u9178\u30ab\u30eb\u30b7\u30a6\u30e0\uff09\u3067\u3067\u304d\u305f\u786c\u3044\u6c88\u7740\u7269\u304c\u84c4\u7a4d\u3059\u308b\u4e00\u822c\u7684\u306a\u72b6\u614b\u3067\u3059\u3002 \u3053\u306e\u72b6\u614b\u3092\u767a\u75c7\u3059\u308b\u4eba\u306e\u30ea\u30b9\u30af\u3068\u76f8\u95a2\u3059\u308b\u907a\u4f1d\u7684\u5909\u7570\u306f\u307b\u3068\u3093\u3069\u767a\u898b\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002 \u3053\u306e\u3088\u3046\u306a\u8981\u56e0\u3092\u767a\u898b\u3059\u308b\u305f\u3081\u306b\u3001\u3053\u306e\u7814\u7a76\u3067\u306f\u30a2\u30a4\u30b9\u30e9\u30f3\u30c9\u3068\u30aa\u30e9\u30f3\u30c0\u306e46,283\u4eba\u3092\u8abf\u67fb\u3057\u307e\u3057\u305f\u3002 \u3053\u306e\u7814\u7a76\u306f\u3001\u3053\u306e\u72b6\u614b\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3068\u76f8\u95a2\u3057\u3066\u3044\u308b\u3068\u601d\u308f\u308c\u308bCLDN14\u907a\u4f1d\u5b50\u306e\u907a\u4f1d\u7684\u5909\u7570\u3092\u7279\u5b9a\u3057\u307e\u3057\u305f\u3002 \u3053\u306e\u907a\u4f1d\u5b50\u306f\u30d8\u30f3\u30ec\u30eb\u30fc\u30d7\uff08\u814e\u81d3\u306e\u4e00\u90e8\u3067\u3001\u6c34\u3068\u5869\u304c\u8840\u6db2\u306b\u518d\u5438\u53ce\u3055\u308c\u308b\u90e8\u5206\uff09\u3067\u767a\u73fe\u3057\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u306e\u8f38\u9001\u3092\u52a9\u3051\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u3053\u306e\u5909\u7570\u4f53\u306f\u3001\u5c3f\u4e2d\u30ab\u30eb\u30b7\u30a6\u30e0\u30ec\u30d9\u30eb\u3068\u9aa8\u5869\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u306b\u3082\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n<p><strong>\u77e5\u3063\u3066\u307e\u3059\u304b\uff1f<\/strong>\u305f\u304f\u3055\u3093\u306e\u6c34\u3092\u98f2\u3080\u3053\u3068\u306f\u3001\u3053\u306e\u814e\u81d3\u75c5\u3092\u767a\u75c7\u3057\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u305f\u3081\u306e\u6700\u826f\u306e\u65b9\u6cd5\u306e1\u3064\u3067\u3059\u3002\u305d\u306e\u4ed6\u306e\u4e88\u9632\u7b56\u306b\u306f\u3001\u98df\u4e8b\u4e2d\u306e\u30ca\u30c8\u30ea\u30a6\u30e0\u3068\u8d64\u8eab\u306e\u8089\u3092\u6e1b\u3089\u3059\u3053\u3068\u3084\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u8c4a\u5bcc\u306a\u98df\u54c1\u3068\u30b7\u30e5\u30a6\u9178\u5869\u304c\u8c4a\u5bcc\u306a\u98df\u54c1\uff08\u307b\u3046\u308c\u3093\u8349\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u3001\u30eb\u30d0\u30fc\u30d6\u3001\u30c1\u30e7\u30b3\u30ec\u30fc\u30c8\u306a\u3069\uff09\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u304c\u542b\u307e\u308c\u307e\u3059\u3002 [<a href=\"https:\/\/www.kidney.org\/atoz\/content\/kidneystones_prevent\">\u30bd\u30fc\u30b9<\/a>]<\/p>\n\n<p><strong>\u30b5\u30f3\u30d7\u30eb\u7d50\u679c\uff1a<\/strong>\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/nebula.org\/blog\/ja\/nebula-library-unlocking-genetic-research\/\">\u661f\u96f2\u7814\u7a76\u56f3\u66f8\u9928<\/a>\u3002<\/p>\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/nebula.org\/free-dna-upload-analysis\/\"><img decoding=\"async\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png\" alt=\"&#x814E;&#x81D3;&#x7D50;&#x77F3;&#x306E;&#x30B5;&#x30F3;&#x30D7;&#x30EB;&#x30EC;&#x30DD;&#x30FC;&#x30C8;&#x3002;\"\/><\/a><\/figure>\n\n<p><\/p>\n\n<p><strong>\u814e\u81d3\u7d50\u77f3-\u95a2\u9023\u3059\u308b\u5909\u7570\u4f53\uff1a<\/strong> rs219779<\/p>\n\n<p><strong>\u8ffd\u52a0\u306e\u30ea\u30bd\u30fc\u30b9\uff1a<\/strong> <br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/kidney-stones\/symptoms-causes\/syc-20355755\" target=\"_blank\">\u814e\u81d3\u7d50\u77f3\u306e\u6982\u8981<\/a><br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/en.wikipedia.org\/wiki\/Calcium_oxalate\" target=\"_blank\">\u30b7\u30e5\u30a6\u9178\u30ab\u30eb\u30b7\u30a6\u30e0<\/a><br\/><a rel=\"noreferrer noopener\" href=\"https:\/\/www.britannica.com\/science\/loop-of-Henle\" target=\"_blank\">\u30d8\u30f3\u30ec\u30eb\u30fc\u30d7<\/a><\/p>\n\n<p><strong>\u6bce\u9031\u306e\u66f4\u65b0\uff1a<\/strong> 2019\u5e747\u670823\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u30bf\u30a4\u30c8\u30eb\uff1a CLDN14\u907a\u4f1d\u5b50\u306e\u914d\u5217\u5909\u7570\u4f53\u306f\u814e\u81d3\u7d50\u77f3\u3068\u9aa8\u5869\u5bc6\u5ea6\u306b\u95a2\u9023\u3057\u3066\u3044\u307e &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/ja\/%e8%85%8e%e8%87%93%e7%b5%90%e7%9f%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%a6-thorleifsson-2009\/\"> <span class=\"screen-reader-text\">\u814e\u81d3\u7d50\u77f3\uff08Thorleifsson\u30012009\u5e74\uff09<\/span> Read More 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