{"id":12924,"date":"2021-01-31T17:16:02","date_gmt":"2021-01-31T22:16:02","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-da-queda-risco-trajanoska-2020\/"},"modified":"2021-02-20T20:23:04","modified_gmt":"2021-02-21T01:23:04","slug":"genetica-da-queda-risco-trajanoska-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/genetica-da-queda-risco-trajanoska-2020\/","title":{"rendered":"Queda (Trajanoska, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> Base gen\u00e9tica da suscetibilidade ao risco de queda no estudo do Biobank no Reino Unido<\/a><\/p>\n\n

RESUMO:<\/strong> Descoberta de 3 regi\u00f5es gen\u00f4micas associadas a um risco aumentado de queda.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> As quedas s\u00e3o a principal causa de les\u00f5es entre os adultos mais velhos, com mais de um ter\u00e7o de todos os americanos com mais de 65 anos sofrendo uma queda a cada ano. Para algumas les\u00f5es, como fraturas de quadril, at\u00e9 90% ocorrem como resultado de quedas. Como muitos fatores que levam \u00e0 queda, como a cogni\u00e7\u00e3o e a fun\u00e7\u00e3o muscular, t\u00eam um componente gen\u00e9tico, este estudo buscou encontrar fatores gen\u00e9ticos diretamente associados ao aumento do risco de queda. O estudo examinou os genomas de mais de 450.000 indiv\u00edduos de ascend\u00eancia europeia e identificou 3 regi\u00f5es gen\u00f4micas associadas a um risco aumentado de queda. Diversas variantes foram localizadas em genes importantes para o desenvolvimento do c\u00f3rtex cerebral, regi\u00e3o com importantes fun\u00e7\u00f5es sensoriais e motoras. No geral, o estudo descobriu que quase 3% do risco de queda de um indiv\u00edduo pode ser determinado pela gen\u00e9tica. O estudo tamb\u00e9m descobriu que condi\u00e7\u00f5es como ins\u00f4nia e depress\u00e3o est\u00e3o correlacionadas com um risco aumentado de queda, enquanto o bem-estar e a intelig\u00eancia foram correlacionados com uma diminui\u00e7\u00e3o do risco.<\/p>\n\n

VOC\u00ca SABIA?<\/strong> Certas atividades f\u00edsicas podem ajudar a prevenir quedas em pessoas com risco aumentado. Isso pode incluir atividades como caminhadas regulares e exerc\u00edcios como tai chi, que podem melhorar o equil\u00edbrio e a for\u00e7a. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> .<\/p>\n\n

\"resultados<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ASSOCIADAS A RISCO DE QUEDA:<\/strong> rs2709062, rs2111530, rs2431108<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>Previna quedas e fraturas<\/a>15 maneiras de reduzir o risco de queda (V\u00eddeo)<\/a><\/p>\n\n

VOC\u00ca TAMB\u00c9M PODE ESTAR INTERESSADO EM:<\/strong> Envelhecimento acelerado (Gibson, 2019)<\/a>Healthspan (Timmers, 2020)<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 10 de outubro de 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: Base gen\u00e9tica da suscetibilidade ao risco de queda no estudo do Biobank no Reino Unido RESUMO: Descoberta de 3 regi\u00f5es gen\u00f4micas associadas a um risco aumentado de queda. VIS\u00c3O GERAL: As quedas s\u00e3o a principal causa de …<\/p>\n

Queda (Trajanoska, 2020)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":12927,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-12924","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA 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