{"id":12936,"date":"2021-01-31T17:16:07","date_gmt":"2021-01-31T22:16:07","guid":{"rendered":"https:\/\/nebula.org\/blog\/qualidade-do-sono-khoury-2020\/"},"modified":"2021-02-20T20:27:31","modified_gmt":"2021-02-21T01:27:31","slug":"qualidade-do-sono-khoury-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/qualidade-do-sono-khoury-2020\/","title":{"rendered":"Qualidade do sono (Khoury, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> O GWAS multi\u00e9tnico e a meta-an\u00e1lise da qualidade do sono identificam o MPP6 como um novo gene que funciona nos neur\u00f4nios centrais do sono<\/a><\/p>\n\n

RESUMO:<\/strong> Identifica\u00e7\u00e3o de 3 regi\u00f5es do genoma associadas \u00e0 qualidade do sono.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> A qualidade do sono \u00e9 muito importante para a sa\u00fade geral e o bem-estar de uma pessoa. Foi demonstrado que o sono insuficiente pode causar v\u00e1rios problemas de sa\u00fade, desde doen\u00e7as card\u00edacas at\u00e9 depress\u00e3o. A qualidade do sono \u00e9 determinada por v\u00e1rios fatores, incluindo a dura\u00e7\u00e3o do sono, o tempo que leva para adormecer e o n\u00famero de vezes que uma pessoa acorda durante a noite. Estima-se que fatores gen\u00e9ticos podem explicar mais de 30% da varia\u00e7\u00e3o observada na qualidade do sono. Para identificar esses fatores gen\u00e9ticos, este estudo de associa\u00e7\u00e3o do genoma examinou mais de 100.000 indiv\u00edduos em diferentes etnias. O estudo descobriu tr\u00eas regi\u00f5es do genoma associadas \u00e0 qualidade do sono. Um dos genes envolvidos, o ATOH8, \u00e9 conhecido por desempenhar um papel no desenvolvimento do c\u00e9rebro, rins e outros \u00f3rg\u00e3os. Outra variante est\u00e1 localizada entre dois genes: NPY e MPP6. Ambos os genes s\u00e3o conhecidos por serem ativos no c\u00e9rebro, e o NPY em particular foi encontrado anteriormente para ajudar a regular o processo do sono.<\/p>\n\n

VOC\u00ca SABIA?<\/strong> O exerc\u00edcio regular, talvez t\u00e3o pouco quanto 10-30 minutos por dia, pode ajudar a melhorar a qualidade do sono. Al\u00e9m disso, exercitar-se pela manh\u00e3 ou \u00e0 tarde pode ser mais ben\u00e9fico para a qualidade do sono do que malhar \u00e0 noite. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> .<\/p>\n\n

\"resultados<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ASSOCIADAS \u00c0 QUALIDADE DO SONO:<\/strong> rs11976703, rs609869707, rs78633772<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>A ci\u00eancia do sono (V\u00eddeo)<\/a>10 dicas para dormir mais<\/a><\/p>\n\n

VOC\u00ca TAMB\u00c9M PODE ESTAR INTERESSADO EM:<\/strong> Sonol\u00eancia diurna (Wang, 2019)<\/a>Ronco (Campos, 2020)<\/a>Bem-estar (Baselmans, 2019)<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 1 de novembro de 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: O GWAS multi\u00e9tnico e a meta-an\u00e1lise da qualidade do sono identificam o MPP6 como um novo gene que funciona nos neur\u00f4nios centrais do sono RESUMO: Identifica\u00e7\u00e3o de 3 regi\u00f5es do genoma associadas \u00e0 qualidade do sono. VIS\u00c3O …<\/p>\n

Qualidade do sono (Khoury, 2020)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":12939,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-12936","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA 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