{"id":12967,"date":"2021-01-31T17:16:17","date_gmt":"2021-01-31T22:16:17","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-polipos-nasais-2019\/"},"modified":"2021-02-20T20:59:10","modified_gmt":"2021-02-21T01:59:10","slug":"genetica-de-polipos-nasais-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-polipos-nasais-2019\/","title":{"rendered":"P\u00f3lipos nasais (Kristjansson, 2019)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> Uma variante de perda de fun\u00e7\u00e3o em ALOX15 protege contra p\u00f3lipos nasais e rinossinusite cr\u00f4nica<\/a><\/p>\n\n

RESUMO:<\/strong> Identifica\u00e7\u00e3o de 10 variantes gen\u00e9ticas associadas ao desenvolvimento de p\u00f3lipos nasais.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> Os p\u00f3lipos nasais s\u00e3o crescimentos que se formam ao longo do revestimento da cavidade nasal. Embora n\u00e3o sejam cancer\u00edgenos, eles podem eventualmente causar bloqueio da passagem nasal, levando a problemas respirat\u00f3rios e perda do olfato. No momento da publica\u00e7\u00e3o deste estudo, nenhum fator de risco gen\u00e9tico para p\u00f3lipo nasal era conhecido. Este estudo examinou os genomas de mais de 700.000 indiv\u00edduos de ascend\u00eancia europeia e descobriu 10 variantes gen\u00e9ticas, muitos genes pr\u00f3ximos que desempenham um papel na inflama\u00e7\u00e3o. Foi relatado anteriormente que a inflama\u00e7\u00e3o nasal cr\u00f4nica aumenta o risco de desenvolver p\u00f3lipos nasais. Os resultados deste estudo lan\u00e7am alguma luz sobre esta conex\u00e3o.<\/p>\n\n

VOC\u00ca SABIA?<\/strong> Como o ar seco pode desencadear a inflama\u00e7\u00e3o da cavidade nasal, o uso de um umidificador pode ajudar a prevenir a inflama\u00e7\u00e3o recorrente e o desenvolvimento de p\u00f3lipos. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ASSOCIADOS AO POLIP:<\/strong> rs1391371, rs1888909, rs1837253, rs34210653, rs1444782, rs17718444, rs338598, rs6543124, rs174535, rs1050152<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>P\u00f3lipos nasais<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 26 de dezembro de 2019<\/p>\n\n

<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: Uma variante de perda de fun\u00e7\u00e3o em ALOX15 protege contra p\u00f3lipos nasais e rinossinusite cr\u00f4nica RESUMO: Identifica\u00e7\u00e3o de 10 variantes gen\u00e9ticas associadas ao desenvolvimento de p\u00f3lipos nasais. VIS\u00c3O GERAL: Os p\u00f3lipos nasais s\u00e3o crescimentos que se formam …<\/p>\n

P\u00f3lipos nasais (Kristjansson, 2019)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":12976,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-12967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA 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