{"id":13164,"date":"2021-01-31T22:13:42","date_gmt":"2021-02-01T03:13:42","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-moles-falchi-2009\/"},"modified":"2021-02-20T20:28:04","modified_gmt":"2021-02-21T01:28:04","slug":"genetica-de-moles-falchi-2009","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/","title":{"rendered":"Moles (Falchi, 2009)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> Estudo de associa\u00e7\u00e3o de todo o genoma identifica variantes em 9p21 e 22q13 associadas ao desenvolvimento de nevos cut\u00e2neos<\/a><\/p>\n\n

RESUMO:<\/strong> Identifica\u00e7\u00e3o de 2 regi\u00f5es gen\u00f4micas associadas ao n\u00famero de toupeiras no corpo. <\/p>\n\n

VIS\u00c3O GERAL:<\/strong> Moles s\u00e3o les\u00f5es cut\u00e2neas pigmentadas, geralmente se desenvolvendo durante a idade adulta em \u00e1reas da pele expostas ao sol. Na maioria dos casos, as toupeiras s\u00e3o benignas e n\u00e3o requerem tratamento. No entanto, \u00e0s vezes eles se transformam em c\u00e2ncer de pele. A contagem de manchas no corpo \u00e9 o fator de risco conhecido mais forte para melanoma, um tipo de c\u00e2ncer que se desenvolve a partir de c\u00e9lulas produtoras de pigmento. Este estudo examinou a predisposi\u00e7\u00e3o gen\u00e9tica para desenvolver moles, examinando os genomas de mais de 1500 indiv\u00edduos de ascend\u00eancia europeia. O estudo descobriu 2 regi\u00f5es gen\u00f4micas que est\u00e3o significativamente associadas a essa caracter\u00edstica. As variantes gen\u00e9ticas nessas regi\u00f5es tamb\u00e9m foram diretamente relacionadas ao melanoma em estudos anteriores. <\/p>\n\n

VOC\u00ca SABIA?<\/strong> A maioria das pessoas tem de 10 a 40 moles. Eles podem mudar na apar\u00eancia ou desaparecer com o tempo. As mudan\u00e7as hormonais da adolesc\u00eancia e gravidez podem fazer com que eles se tornem mais escuros e maiores. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> . <\/p>\n\n

\"resultados<\/a><\/figure>\n\n

VARIANTES ASSOCIADAS AO ESTUDO:<\/strong> rs4636294, rs2284063<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>Sinais de alerta de melanoma<\/a>Os 4 est\u00e1gios do melanoma (v\u00eddeo)<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 28 de abril de 2020<\/p>\n\n

Al\u00e9m disso, d\u00ea uma olhada em nosso Revis\u00e3o de curologia<\/a> !<\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: Estudo de associa\u00e7\u00e3o de todo o genoma identifica variantes em 9p21 e 22q13 associadas ao desenvolvimento de nevos cut\u00e2neos RESUMO: Identifica\u00e7\u00e3o de 2 regi\u00f5es gen\u00f4micas associadas ao n\u00famero de toupeiras no corpo. VIS\u00c3O GERAL: Moles s\u00e3o les\u00f5es …<\/p>\n

Moles (Falchi, 2009)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":13168,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-13164","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA gen\u00e9tica do desenvolvimento das toupeiras (Falchi, 2009)<\/title>\n<meta name=\"description\" content=\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao desenvolvimento de toupeiras (Falchi, 2009) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A gen\u00e9tica do desenvolvimento das toupeiras (Falchi, 2009)\" \/>\n<meta property=\"og:description\" content=\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao desenvolvimento de toupeiras (Falchi, 2009) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-01T03:13:42+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-02-21T01:28:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/04\/chris-slupski-ckMxc3LxhMo-unsplash-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Moles (Falchi, 2009)\",\"datePublished\":\"2021-02-01T03:13:42+00:00\",\"dateModified\":\"2021-02-21T01:28:04+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\"},\"wordCount\":271,\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#organization\"},\"articleSection\":[\"Reports\"],\"inLanguage\":\"pt-BR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\",\"url\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\",\"name\":\"A gen\u00e9tica do desenvolvimento das toupeiras (Falchi, 2009)\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#website\"},\"datePublished\":\"2021-02-01T03:13:42+00:00\",\"dateModified\":\"2021-02-21T01:28:04+00:00\",\"description\":\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao desenvolvimento de toupeiras (Falchi, 2009) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.\",\"breadcrumb\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nebula.org\/blog\/pt-br\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Moles (Falchi, 2009)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#website\",\"url\":\"https:\/\/nebula.org\/blog\/pt-br\/\",\"name\":\"Nebula Genomics Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nebula.org\/blog\/pt-br\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#organization\",\"name\":\"Nebula Genomics\",\"url\":\"https:\/\/nebula.org\/blog\/pt-br\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Nebula Genomics\"},\"image\":{\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/facebook.com\/nebulagenomics\",\"https:\/\/twitter.com\/nebulagenomics\",\"https:\/\/www.instagram.com\/nebulagenomics\/\",\"https:\/\/www.linkedin.com\/company\/nebula-genomics\/\",\"https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\",\"name\":\"Garrett Dunlap, B.S.\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"caption\":\"Garrett Dunlap, B.S.\"},\"description\":\"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.\",\"sameAs\":[\"https:\/\/nebula.org\/whole-genome-sequencing\/\"],\"url\":\"https:\/\/nebula.org\/blog\/pt-br\/author\/garrett-dunlap\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A gen\u00e9tica do desenvolvimento das toupeiras (Falchi, 2009)","description":"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao desenvolvimento de toupeiras (Falchi, 2009) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/","og_locale":"pt_BR","og_type":"article","og_title":"A gen\u00e9tica do desenvolvimento das toupeiras (Falchi, 2009)","og_description":"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao desenvolvimento de toupeiras (Falchi, 2009) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.","og_url":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/","og_site_name":"Nebula Genomics Blog","article_publisher":"https:\/\/facebook.com\/nebulagenomics","article_published_time":"2021-02-01T03:13:42+00:00","article_modified_time":"2021-02-21T01:28:04+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/04\/chris-slupski-ckMxc3LxhMo-unsplash-scaled.jpg","type":"image\/jpeg"}],"author":"Garrett Dunlap, B.S.","twitter_card":"summary_large_image","twitter_creator":"@nebulagenomics","twitter_site":"@nebulagenomics","twitter_misc":{"Escrito por":"Garrett Dunlap, B.S.","Est. tempo de leitura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/#article","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/"},"author":{"name":"Garrett Dunlap, B.S.","@id":"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e"},"headline":"Moles (Falchi, 2009)","datePublished":"2021-02-01T03:13:42+00:00","dateModified":"2021-02-21T01:28:04+00:00","mainEntityOfPage":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/"},"wordCount":271,"publisher":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/#organization"},"articleSection":["Reports"],"inLanguage":"pt-BR"},{"@type":"WebPage","@id":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/","url":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/","name":"A gen\u00e9tica do desenvolvimento das toupeiras (Falchi, 2009)","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/#website"},"datePublished":"2021-02-01T03:13:42+00:00","dateModified":"2021-02-21T01:28:04+00:00","description":"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao desenvolvimento de toupeiras (Falchi, 2009) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.","breadcrumb":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-moles-falchi-2009\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nebula.org\/blog\/pt-br\/"},{"@type":"ListItem","position":2,"name":"Moles (Falchi, 2009)"}]},{"@type":"WebSite","@id":"https:\/\/nebula.org\/blog\/pt-br\/#website","url":"https:\/\/nebula.org\/blog\/pt-br\/","name":"Nebula Genomics Blog","description":"","publisher":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nebula.org\/blog\/pt-br\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/nebula.org\/blog\/pt-br\/#organization","name":"Nebula Genomics","url":"https:\/\/nebula.org\/blog\/pt-br\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Nebula Genomics"},"image":{"@id":"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/facebook.com\/nebulagenomics","https:\/\/twitter.com\/nebulagenomics","https:\/\/www.instagram.com\/nebulagenomics\/","https:\/\/www.linkedin.com\/company\/nebula-genomics\/","https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics"]},{"@type":"Person","@id":"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e","name":"Garrett Dunlap, B.S.","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nebula.org\/blog\/pt-br\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","caption":"Garrett Dunlap, B.S."},"description":"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/pt-br\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/posts\/13164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/comments?post=13164"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/posts\/13164\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/media\/13168"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/media?parent=13164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/categories?post=13164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/pt-br\/wp-json\/wp\/v2\/tags?post=13164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}